丙烯腈作业工人尿硫氰酸盐水平及健康效应 |
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引用本文: | 李环,郑扬,艾丽莎. 丙烯腈作业工人尿硫氰酸盐水平及健康效应[J]. 环境与职业医学, 2012, 29(9): 561-562 |
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作者姓名: | 李环 郑扬 艾丽莎 |
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作者单位: | 李环 (盘锦市疾病预防控制中心体检科,辽宁盘锦,124010) ; 郑扬 (盘锦市疾病预防控制中心体检科,辽宁盘锦,124010) ; 艾丽莎 (盘锦市疾病预防控制中心体检科,辽宁盘锦,124010) ; |
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摘 要: | [目的]调查接触低水平丙烯腈作业工人的尿硫氰酸盐浓度及健康效应,探讨其是否可作为低水平丙烯腈暴露的接触指标。[方法]选取某化工企业接触丙烯腈工人315名作为研究对象,进行常规职业健康检查,并采用吡啶一巴比妥酸比色法测定尿硫氰酸盐浓度。[结果]丙烯腈作业工人尿硫氰酸盐浓度呈正偏态分布,中位数为4.95mg/L,四分位间距为4.84mg/L。尿硫氰酸盐浓度与吸烟、饮酒及其他健康效应均未显示出统计学关联。[结论]尿硫氰酸盐含量不能作为低水平丙烯腈暴露的接触指标。
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关 键 词: | 丙烯腈 尿硫氰酸盐 尿样 健康效应 |
Urinary Thiocyanate Levels and Health Effects in Workers Exposed to Acrylonitrile |
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Affiliation: | LI Huan, ZHENG Yang, XI Li-sha (Physical Examination Department, Panjin Center for Disease Control and Prevention, Panjin, Liaoning 124010, China) |
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Abstract: | [ Objective ] To determine the levels and health effects of urinary thiocyanate (USCN) in workers exposed to low-level acrylonitrile, and to discuss if USCN levels can be used as an indicator of low-level acrylonitrile exposure. [ Methods ] A total of 315 workers from a chemical factory located in Panjin city were recruited as study subjects and received occupational health examination. The USCN levels were determined by pyrideine-barbituric acid spectrophotometry. [ Results ] The distribution of USCN levels was positively skewed, its median was 4.95 mg/L and the inter-quartile range was 4.84 mg/L. No significant associations of USCN levels were observed with alcohol consumption, cigarette smoking, and other health parameters. [ Conclusion ] Thiocyanate level in random urine samples is not capable of serving as a biomarker of low-level acrylonitrile exposure. |
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Keywords: | acrylonitrile urinary thiocyanate urine samples health effects |
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