老年患者二重真菌感染与抗菌药物应用分析

目的 探讨老年患二重真菌感染与抗菌药物应用的关系。方法 对我院106例老年住院患应用抗菌药物后的二重真菌感染情况进行回顾分析。结果 ≥60％老年患大多患有严重的基础疾病，免疫力弱，平均住院时间长，抗菌药物诱发的二重真菌感染是引起院内真菌感染的主要原因之一，占我院同期发生老年患真菌感染的84．6％。感染部位以肺部为主，其次为尿道。结论 长期应用广谱抗菌药物是导致老年患院内二重真菌感染增多的主要因素。

Analysis of mycotic superinfections and the use of antimicrobials in senile patients

AIM To study the relation between mycotic superinfections and use of antimicrobials in senile patients. METHODS 106 senile in patients who had mycotic superinfections following administration of antimicrobials were retrospectively andysed. RESULTS Most of the senil patients over 60 years of age had severe underlying diseases and hypoimmunity and needed staying hospital for long time. Antimierobial iuduced mycotic superinfection played an important role in leading to mycotic infection in hospital accounting for 84 6% of total mycotic infection in our hospital during the corresponding period. Pulmonary infection was the commonest one and urinary tract infection the next. CONCLUSION Long term use of broad spectrun antimicrobials is the main contributing factor resulting in increase of mycotic superinfections of senile patients in hospital.