甲状腺癌发生发展及预后的相关影响因素

甲状腺癌是头颈部及内分泌系统中最常见的恶性肿瘤之一，发病率逐年增加，尽管诊疗手段不断提高、总体死亡率也并未显著上升，但新增病例的不断出现已引起全球医疗界的高度关注。甲状腺癌的发生、发展及预后受患者年龄、性别、精神心理因素、环境因素、遗传因素、病理组织学类型、淋巴结转移、临床分期、免疫组织化学因素、分子生物学等诸多因素影响，其中肿瘤分期与组织学类型是甲状腺癌预后的主要影响因素。了解影响甲状腺癌预后的各种因素，对指导治疗、判断预后意义重大，根据预后因素的不同选择恰当的个体化综合治疗方案，以期使患者最大获益。

Related factors of occurrence,development and prognosis of thyroid cancer

Thyroid cancer is one of the most common malignant tumors in the head,neck and endocrine system.The incidence of thyroid cancer has been increasing year by year.Although the diagnosis and treatment methods are constantly improving and the overall mortality rate is not significantly increasing,the continuous emergence of new cases has attracted the attention of the global medical community.The cause of thyroid cancer is not very clear.The occurrence,development and prognosis of thyroid cancer are affected by many factors:age,gender,psychomental factor,environmental factor,genetic factor,histopathological type,lymph node metastasis,clinical stage,immunohistochemical factor,molecular biological factor,and so on.It is of great significance to find out the factors that may affect the prognosis of thyroid cancer for guiding treatment and judging prognosis.According to the different prognostic factors,we can choose the appropriate individualized comprehensive treatment plan in order to maximize the benefits of patients.