发热待查254例临床分析

目的 探讨发热待查(FUO)的病因及发病趋势,以利于临床早期诊断.方法 回顾性地分析1994-2005年宁夏医学院附属医院收治的符合FUO诊断标准、年龄≥14岁的254例患者的临床资料.结果 254例患者通过多种方法最终确诊223例(87.8%),包括感染性疾病123例(48.4%),其中结核病23例,占感染性疾病的18.7%;结缔组织病40例(15.7%);肿瘤性疾病21例(8.3%);其他疾病39例(15.4%).最终仍原因不明者31例(12.2%).1994-1999年与2000-2005年的资料相比,结核病、恶性肿瘤及原因不明者比例增加,伤寒比例减少.结论 感染性疾病是发热待查的主要病因,其次为结缔组织病和肿瘤性疾病.

Clinical analysis of 254 cases with fever of unknown origin

Objective To investigate the cause and tendency of fever of unknown origin(FUO).Methods A retrospective study was designed to analyze 254 cases of FUO which were in hospital of the Affiliated Hosp.Of Ningxia Med.Coll.from 1994 to 2005,which were corresponding to the standard of FUO and elder than 14 years old.Results 223 of 254 cases were made the diagnosis at last.The most common causes of FUO were infectious disease(48.4%),with tuberculosis accounting for 18.7%(23/123) of cases of infection.21 patients(8.3%) were suffered from malignancy.40 patients(15.7%) were diagnosed as connective tissue diseases.Miscellaneous causes were found in 15.4% of the FUO cases.However,indefinited diagnosis had been made in the remaining 31(12.2%) cases until they discharged from the hospital.The mobility of tuberculosis,malignancy and non-diagnosis of 1994-1999 was higher than 2000-2005,however typhoid fever became lower.Conclusion Infectious disease is the most common causes of FUO while the second were connective tissue diseases and malignancy.