| 奥氮平对首发精神分裂症患者的疗效及认知功能影响 |
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| 引用本文： | 王晓枫. 奥氮平对首发精神分裂症患者的疗效及认知功能影响[J]. 四川精神卫生, 2008, 21(4): 217-219 |
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| 作者姓名： | 王晓枫 |
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| 作者单位： | 山东省临沂市精神卫生中心,276005 |
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| 摘 要： | 目的观察奥氮平对首发精神分裂症患者的疗效及认知功能的影响。方法对31例首发精神分裂症患者在奥氮平治疗前及治疗12周后，用阳性症状量表（SAPS）、阴性症状量表（SANS）、韦氏成人智力量表（WAIS—R）、韦氏记忆量表（WMS）、简明精神病评定量表（BPRS）、韦斯康星卡片分类测验（WCST）进行评估，并观察奥氮平对精神分裂症症状的疗效及对认知功能的影响。结果治疗后SAPS、SANS、BPRS〈WCST中错误应答数的评估分值显著降低（P〈0．01），且非持续性错误、WMS的再生、理解评估分值也明显降低（P〈0．05）。结论奥氮平治疗精神分裂症疗效可靠并可显著改善部分患者的认知功能。
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| 关 键 词： | 奥氮平 精神分裂症 认知功能 |
The efficacy and congnitive function of olanzapine in the treatment of first-episode schizophrenic patients |
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| WANG Xiaofeng. The efficacy and congnitive function of olanzapine in the treatment of first-episode schizophrenic patients[J]. Sichuan Mental Health, 2008, 21(4): 217-219 |
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| Authors: | WANG Xiaofeng |
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| Affiliation: | WANG Xiaofeng.The Mental Health Center of Linyi,Sh,ong 276005,China |
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| Abstract: | Objective To investigate the efficacy and congnitive function of olanzapine in the treatment of first-episode schizophrenic patients.Methods A total of 31 patients of first-episode schizophrenic were treated by olanzapine 12 weeks and evaluated with SAPS,SANS,WAIS-R,WMS,BPRS,WCST before and after treatment.Results After treatment the score of SAPS,SANS,BPRS,WCST'S faultanswer were reduced nobably(P<0.01),the score of WCST'S un-durative fault,WMS'S reactive and prehension wer reduced notably(P<0.05).Conclusi... |
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| Keywords: | Olanzapine Schizophrenia Congnitive function |
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