阻塞性睡眠呼吸暂停低通气综合征 患者抑郁状况及相关因素分析

目的：调查阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者的抑郁状况及其影响因素。方法：对114例经多导睡眠图确诊的OSAHS患者进行调查。主要研究工具包括自编的一般情况调查表、贝克抑郁量表（BDI）、Epworth嗜睡量表(ESS)、匹兹堡睡眠质量指数（PSQI）和简易应对方式问卷。结果：OSAHS患者的BDI得分为（8.29±6.46）分。以BDI 10分为界,抑郁症状的发生率为32.5%。应对方式、PSQI总分及主观睡眠质量、睡眠时间、睡眠效率、睡眠紊乱、使用催眠药物、日间功能障碍因子与抑郁呈正相关。ESS、体质量指数（BMI）、呼吸暂停低通气指数(AHI)、最低氧饱和度(LSaO2)、平均氧饱和度(MSaO2)与抑郁得分均无相关。结论：约1/3的OSAHS患者伴有抑郁症状;PSQI总分、消极应对方式、积极应对方式、使用催眠药物、入睡时间是患者抑郁状况的主要影响因素。

Depressive symptom and correlative factors in patients with obstructive sleep apnea-hypopnea syndrome

ObjectiveTo investigate the depression and its influencing factors in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).MethodsThe scales of the demographic data, Epworth sleepiness scale (ESS), Pittsburgh sleep quality index (PSQI), Beck depression inventory(BDI), and simplified coping style questionnaire (SCSQ) were tested in 114 patients with OSAHS. ResultsThe BDI score was (8.29±6.46), and 32.5% of the patients had depression. The BDI score was related to the coping style, PSQI total score and the subjective sleep quality, sleep time, sleep efficiency, sleep disturbance, using hypnotic drugs, and day-time dysfunction. There were no correlations between the ESS, body mass index, apnea hyponea index(AHI), lowest oxygen saturation (LSaO2), mean oxygen saturation (MSaO2) and depression.ConclusionAbout 1/3 of the OSAHS patients have depressive symptoms. PSQI score,negative coping style, positive coping style, using hypnotic drugs, and time for falling asleep are influential factors in OSAHS patients.