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Remitting seronegative symmetrical synovitis with pitting edema following acute intracranial hemorrhage
Authors:Deng-Ho Yang  Deh-Ming Chang  Jenn-Haung Lai  Guo-Shu Huang  Wei-Chou Chang  Tsung-Yun Hou
Institution:(1) Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Armed-Forces Taichung General Hospital, No. 348, Sec. 2, Chung-Shan Rd, Taiping 411, Taichung, Taiwan, Republic of China;(2) Division of Rheumatology/Immunology/Allergy, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-Kung Rd, Neihu 114, Taipei, Taiwan, Republic of China;(3) Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China;
Abstract:Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is an unusual inflammatory arthritis with unknown pathogenic mechanism, and is characterized by an acute onset of symmetrical synovitis with pitting edema of the hands or feet. Numerous diseases are associated with RS3PE, including neoplasia, infection, Parkinson’s disease, and other rheumatic diseases. Neoplasia is the most common condition associated with RS3PE. We report a case of RS3PE that occurred following acute intracranial hemorrhage in an 80-year-old man with a 20-year history of hypertension.
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