| 拉米夫定联合苦参素治疗慢性乙型肝炎68例临床观察 |
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| 引用本文： | 王文琦,程元桥. 拉米夫定联合苦参素治疗慢性乙型肝炎68例临床观察[J]. 实用肝脏病杂志, 2005, 8(2): 83-84 |
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| 作者姓名： | 王文琦 程元桥 |
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| 作者单位： | 523018,广东省东莞市,东莞市人民医院感染科 |
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| 摘 要： | 目的 探讨拉米夫定(LAM)联合苦参素治疗慢性乙型肝炎(CHB)患者的临床疗效。方法 将慢性乙型肝炎患者13 4例随机分为治疗组(68例)与对照组(66例)。治疗组给予LAM联合苦参素治疗;对照组单用LAM。疗程6个月,随访6个月。观察治疗前后的血生化,HBeAg ,HBVDNA等指标的变化情况。结果 疗程结束后和停药6个月后,治疗组患者血清HBeAg、HBVDNA等指标显著下降,与对照组比较差异有显著性(P <0 .0 5或P <0 .0 1)。结论 LAM联合苦参素治疗CHB疗效优于LAM单一用药。
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| 关 键 词： | 拉米夫定 素治疗 苦参 临床观察 慢性乙型肝炎患者 HBeAg LAM 对照组 治疗组 临床疗效 治疗前后 变化情况 0．05 单一用药 HBV DNA 血生化 显著性 CHB 疗程 指标 |
| 修稿时间： | 2005-01-16 |
Clinical study of lamivudine combined with kurorinone in the treatment of chronic hepatitis B |
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| Wang Wenqi,Chen Yunqiao. Clinical study of lamivudine combined with kurorinone in the treatment of chronic hepatitis B[J]. Journal of Clinical Hepatology, 2005, 8(2): 83-84 |
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| Authors: | Wang Wenqi Chen Yunqiao |
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| Abstract: | Objective To study the efficacy of lamivudine(LAM)combined with kurorinone in the treatment of chronic hepatitis B.Methods 134 patients with chronic hepatitis B(CHB)were randomly divided into two groups.Patients of the treatment group were given lamivudine 0.1,p.o,q.d,and kurorinone 0.2,p.o,tid,while those of the control group were given lamivudine alone.The course of treatment in both groups lasted for 6 months.Changes in liver function,serum levels of HBeAg,HBV DNA before and after treatment were kept under observation.Results After being treated for 6 months and 6 months after its withdrawal,serum levels of HBeAg,HBV DNA in the treatment group showed significant lower than in the control group(P<0.05 or P<0.01).Conclusion LAM combined with kurorinone is more effective than lamivudine alone for treating patients with chronic hepatitis B. |
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| Keywords: | Hepatitis B Lamivudine Kurorinone |
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