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Socioeconomic status and global variations in the incidence of neuroblastoma: call for support of population‐based cancer registries in low‐middle–income countries
Authors:Junne Kamihara  Clement Ma  Soad Linneth Fuentes Alabi  Claudia Garrido  A. Lindsay Frazier  Carlos Rodriguez‐Galindo  Manuela A. Orjuela
Affiliation:1. Department of Pediatric Oncology, Dana‐Farber Cancer Institute and Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts;2. Department of Oncology, Benjamin Bloom National Children's Hospital, San Salvador, El Salvador;3. National Pediatric Oncology Unit, Francisco Marroquin Medical School, Guatemala City, Guatemala;4. St. Jude Children's Research Hospital, Memphis, Tennessee;5. Department of Epidemiology and Pediatrics (Division of Oncology), Columbia University, New York, New York
Abstract:Global variations in the incidence of pediatric cancers have been described; however, the causes of such differences are not known. We investigated the relationship between the incidence of embryonal tumors and human development index on a global scale. Increasing incidence of neuroblastoma correlates significantly with an increasing index of human development, with greater incidence among countries with high socioeconomic development, in apparent contrast to the incidence of retinoblastoma. While more data are needed to corroborate this observation, our findings suggest new avenues for etiological research and serve as a call for support of population‐based cancer registries in low–middle‐income countries.
Keywords:cancer registries  neuroblastoma  pediatric oncology  socioeconomic status
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