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Cardiac output response to prostaglandin E2-induced abortion in the second trimester
Authors:D C Willis  D Caton  J P Levelle  T Banner
Affiliation:1. Department of Anesthesiology, University of Florida College of Medicine Gainesville, Florida, USA.;2. Department of Obstetrics and Gynecology, University of Florida College of Medicine Gainesville, Florida, USA.;1. Cereal Science Research Center of Tsukuba, Nisshin Flour Milling Inc, 13 Ohkubo, Tsukuba, Ibaraki 300-2611, Japan;2. Whistler Center for Carbohydrate Research, Department of Food Science, Purdue University, West Lafayette, IN, USA;1. Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, USA;2. Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, 12902 USF Magnolia Drive, Tampa, FL 33612, USA;1. Epigenetics and Genome Stability Team, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK;2. Bioinformatics Group, School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QJ, UK;3. Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, UK;1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Egypt;2. Department of Therapeutical Chemistry, National Research Centre, Dokki, Cairo 12622, Egypt;3. Pharmaceutical Sciences Dept., Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, TX, USA;4. Department of Pharmacology, Faculty of Pharmacy, Al-Azhar University, Egypt;5. Inaya Medical College, Riyadh, Saudi Arabia;1. School of Environmental Science & Engineering, Sun Yat-sen University, Guangzhou, 510275, China;2. Department of Environmental Engineering Sciences, Engineering School of Sustainable Infrastructure & Environment, University of Florida, PO Box 116450, Gainesville, FL 32611-6450, USA;3. Experimental Teaching Center, Sun Yat-sen University, Zhuhai Campus, Zhuhai, 519082, China;4. Research Institute of Sun Yat-sen University in Shenzhen, Shenzhen, China
Abstract:Maternal cardiac output changes were evaluated in 10 patients undergoing second-trimester abortion induced by prostaglandin E2 suppositories. The peak cardiac output increased by an average of 64.5% above preinduction values. This is similar to the percent increase described during oxytocin-induced labor at term. Inasmuch as resting cardiac output tends to be higher in midpregnancy than at term, absolute values during prostaglandin E2 induction were higher than those observed in laboring term patients.
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