| 高效液相色谱法测定通腑宁颗粒去氢木香内酯含量 |
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| 引用本文： | 刘德军,慕杨娜. 高效液相色谱法测定通腑宁颗粒去氢木香内酯含量[J]. 实用中医内科杂志, 2013, 0(9): 40-40,76 |
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| 作者姓名： | 刘德军 慕杨娜 |
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| 作者单位： | [1]辽宁中医药大学附属三院制剂中心,沈阳110031 [2]辽宁中医药大学附属第二医院,沈阳110032 |
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| 摘 要： | [目的]建立通腹宁颗粒中去氢木香内酯的含量测定方法。[方法]采用高效液相色谱法，色谱柱：Welchrom-C18（250mm×4．6μm）；流动相：甲醇．水（65：35）；流速：1mL／min；检测波长：225nm；柱温：常温。[结果]回收率RSD=1．11％。检测3批样品通腹宁颗粒中去氢木香内酯含量，限定通腹宁颗粒中去氢木香内酯含量不得低于2．5mg。[结论]高效液相色谱法测定通腹宁颗粒中去氢木香内酯含量，结果准确、可靠，可用于通腹宁颗粒质量控制。
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| 关 键 词： | 高效液相色谱法 通腹宁颗粒 木香 去氢木香内酯 含量测定 |
Determination of Dehydrocostus Lactone in Tongfuning Keli by HPLC |
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| LIU Dejun,MU Yangna. Determination of Dehydrocostus Lactone in Tongfuning Keli by HPLC[J]. , 2013, 0(9): 40-40,76 |
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| Authors: | LIU Dejun MU Yangna |
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| Affiliation: | 1 .Third Hospital of Liaoning University of Traditional Chinese Medicine Preparation Center, Shenyang 10031, China; 2.Second Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Shenyang 110032, China ) |
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| Abstract: | [ Objective ] To establish a method for determing the content of Dehydrocostus lactone in Tongfuning Keli. [ Methods ] The analysis was carried out on Welchrom-C18 （ 250mm ×4.6 μ m ） .Methanol- water （ 65 ： 35 ） as mobile phase .The samples that had been treated by HPLC, desighate 225nm as measuring wavelength. [ Results ] The related standard deviation （ RSD ） was 1.11% ; The contents of Dehydrocostus lactone in 3 batches samples were determined, and the Dehydrocostus lactone content in Tongfuning Keli should not be less than 2.Smg.[ Conclusion ]This method is sensitive and accurate, can be applied in quality control. |
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| Keywords: | HPLC Tongfuning Keli Auekandia root Dehydrocostus lactone Determination |
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