Vertical transmission of HGV and outcome of the infected babies |
| |
Authors: | Dal Molin G D'Agaro P Biagi C Petronio F Comar M Campello C |
| |
Institution: | Dipartimento di Scienze di Medicina Pubblica, UCO Igiene e Medicina Preventiva, Università degli Studi di Trieste, IRCCS Burlo Garofolo Trieste. |
| |
Abstract: | To assess the risk of HGV mother-to-infant transmission and the clinical outcome of infected babies, we investigated 103 mother-infant couples and followed-up the infected children for 4-72 months. Twenty (19.4%) mothers were HGV-RNA positive and transmission occurred in ten (50%) babies; only one child acquired HGV and HCV infection. Maternal factors, such as history of intravenous drug use, HCV-RNA positivity, HIV coinfection, type of delivery and type of feeding were not related to HGV transmission. One HGV infected baby showed a mild hepatitis when he was also infected by Cytomegalovirus. Two babies cleared HGV within the first year of life. The HGV transmission rate is elevated but HGV infection seems to be benign, at least in a short-term follow-up. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|