Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes |
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| Authors: | Lladó A Mannucci P Carpentier A F Paris S Blanco Y Saiz A Delattre J Y Graus F |
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| Affiliation: | Service of Neurology, Hospital Clínic, Universitat de Barcelona, and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona. Spain. |
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| Abstract: | The long-term evolution of Hu antibody (Hu-Ab) titers in patients with paraneoplastic neurologic syndromes (PNSs) is not known. Described is the evolution of Hu-Ab titers in 35 patients with PNS with a median follow-up of 32 months (range 6 to 108 months). No correlation was observed between Hu-Ab titers and neurologic outcome, tumor evolution, or type of treatment. Serial Hu-Ab determinations are not useful for monitoring the clinical outcome of patients with PNS. |
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