银杏达莫结合康复训练对急性脑梗死患者脑循环动力学的影响

目的研究银杏达莫对急性脑梗死患者脑循环动力学的影响。方法将60例首次颈动脉系统急性脑梗死患者随机分为银杏达莫治疗组(治疗组)与常规治疗组(常规组)。采用脑循环动力检测仪分别检测两组患者治疗前、后的脑循环动力学指标(CVDI)。结果急性脑梗死患者经银杏达莫静脉滴注治疗后,颈动脉最小血流速度(Vmin)、颈动脉最小血流量(Qmin)的升高和脑血管阻力(R)降低与常规组相比,差异有统计学意义(P<0.05),治疗组CVDI改善程度明显优于对照组,表明银杏达莫能降低脑血管的阻力,增加脑动脉的供血量,有利于脑功能的恢复。结论银杏达莫能改善急性脑梗死患者脑循环动力学指标,对急性脑梗死患者有较好的治疗作用。

Effect of Yinxingdamo on hemodynamics of cerebral circulation in patients with acute cerebral infarction

Objective To study the effect of Yinxingdamo (compound of ginkgo biloba extract) on hemodynamics of cerebral circulation in patients with acute cerebral infarction (ACI). Methods Sixty patients with first ACI of carotid artery system were randomly divided into a treatment group (30 cases) and a control group (30 cases), and treated with the drug Yinxingdamo plus therapeutic exercise and therapeutic exercise, respectively. The cerebrovascular dynamics indexes (CVDI) of both groups were investigated before and after the treatment. Results The Vmin and Qmin of carotid artery in the two groups were increased after treatment and the cerebrovascular resistance (R) was decreased (P<0.05). The therapeutic effect of treatment group is better than that of the control group. The results showed that Yinxingdamo decreased cerebrovascular resistance and increased cerebral blood velocity and flow. Conclusion It was suggested that Yinxingdamo could improve CVDI of ACI patients and be an effective addition to the treatment of ACI patients.