盾叶薯蓣中有效成分含量的影响因素研究

目的:探讨影响盾叶薯蓣中有效成分含量的因素,更好地控制其质量。方法:参照2010年版《中国药典》(一部)测定水分,高效液相色谱法测定薯蓣皂苷元的含量,对含水量、生长年限、产地及土壤类型与薯蓣皂苷元含量的相关性进行研究。结果:生长在沙土地上的盾叶薯蓣中薯蓣皂苷元含量相对较高,一般生长3~5年薯蓣皂苷元含量达到最大值,而且薯蓣皂苷元含量与盾叶薯蓣根茎中含水量呈正相关,但3个产区的盾叶薯蓣薯蓣皂苷元的含量差别不大。结论:本实验以薯蓣皂苷元为评价盾叶薯蓣质量的指标,分析了生长年限、水分含量、土质、产地等对其质量的影响,为指导工业生产和药农规范化种植,获得更高的经济效益,建立和完善盾叶薯蓣药材的质量标准体系提供参考。

Study of Influence Factors on Content of Effective Component in Dioscorea zingiberensis

Objective: To investigate the factors that affect the effective content in Diascorea zingiherersis and control its quality of D. zingiberensis. Method: According to the method in the Chinese Pharmacopoeia(edition 2010),the water determination was adopted.The content of diosgenin was determined by HPLC. On the basis,the relation of diosgenin content with some factors were analysied,such as resh samples water content,different growth years,different producing areas and different growth soil. Result: The results showed that diosgenin content of D. zingiberensis planted in the sandy landwas relatively high,and generally,the diosgenin content reached the maximum after growth in 3-5 years,the content of diosgenin showed positive linear correlation with water content,but the content diosgenin of D. zingiberensis in three producing areas had little difference. Conclusion: These data provide the reference for standardized planting of D. zingiberensis.