420例非淋球菌性生殖道感染患者的解脲支原体和沙眼衣原体感染分析

目的了解本地区非淋球菌性生殖道感染患者的解脲支原体和沙眼衣原体感染状况。方法利用实时荧光聚合酶链反应方法(FQ-PCR)对2010和2011年来院就诊的420例非淋球菌性生殖道感染患者的泌尿生殖道分泌物同时作解脲支原体和沙眼衣原体检测。结果检出阳性病例211例,阳性率50.0%,(211/420):其中解脲支原体,沙眼衣原体和混合感染的阳性检出率分别为31.9%(134/420),11.7%(49/420)和6.7%(28/420),沙眼衣原体和解脲支原体的感染差异有统计学意义,解脲支原体高于沙眼衣原体;不同性别在不同病原体感染中有所不同,总体上女性感染高于男性(P<0.05),在解脲支原体单一感染差异两性差异有统计学意义(P<0.05),且女性高于男性,但在沙眼衣原体单一感染和两种病原体混合感染中两性差异无统计学意义。结论本地区解脲支原体是非淋球菌性生殖道感染患者的主要病原体,女性呈明显高感染状况,实时荧光聚合酶链反应可作为临床检测的解脲支原体和沙眼衣原体的实验方法。

Analysis of ureaplasma urealyticum and chlamydozoa trachomatis infections in 420 patients with non-gonococcal genitourinary tract infection

Objective To explore the situation of ureaplasma urealyticum(UU) and Chlamydozoa trachomatis(CT) infections in patients with non-gonococcal genitourinary tract infection.Methods A total of 420 samples of urogenital infection were collected during 2010 to 2011.CT and UU were detected in these patients by the method of real-time PCR.Results Among the 420 samples,210 were positive,and the total positive rate was 50.0%(211/420).The positive of UU,CT,and mixed infection was 31.9%(134/420),11.7%(49/420) and 6.7%(28/420),respectively.The infection rate of UU was high according to the statistics(P<0.05).The infection of females was higher than that of males.Females were apt to be infected with UU infection,but there was no difference in the cases of infection with CT and the cases of mixed infection.Conclusion UU is a main pathogen resulting in non-gonococcal genitourinary tract infection.The infection of females is higher than that of males.Real-time PCR method is a rapid sensitive method for the detection of UU and CT.