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玄参不同加工品中哈巴俄苷与肉桂酸的HPLC含量测定
引用本文:王建华,谢丽华,刘洪宇.玄参不同加工品中哈巴俄苷与肉桂酸的HPLC含量测定[J].中国药学杂志,2000,35(6):375-378.
作者姓名:王建华  谢丽华  刘洪宇
作者单位:北京医科大学药学院生药学研究室!北京100083
基金项目:国家九五攻关课题! 96-90 3 -0 2 -0 2
摘    要: 目的 考察不同加工方法对玄参有效成分的影响及其原植物不同部分中有效成分的含量。方法 采用HPLC对玄参的不同加工品及其原植物不同部分进行含量测定。结果 鲜材切片烘干品中有效成分哈巴俄苷含量高于传统加工品,哈巴俄苷在根茎、子芽及须根中含量也较高,但地上部分中未检测出。结论 鲜材切片烘干法可能是玄参较好的一种新的加工方法。根茎、子芽及须根也可作为哈巴俄苷的来源。

关 键 词:玄参  哈巴俄苷  肉桂酸  HPLC
收稿时间:1999-12-24;
修稿时间:1999-12-24

HPLC determination of harpagoside and cinnamic acid in Xuanshen after processed in different methods
WANG Jiang hua,XIE Li hua,LIU Hong yu,WANG Xuan,CAI Shao qin.HPLC determination of harpagoside and cinnamic acid in Xuanshen after processed in different methods[J].Chinese Pharmaceutical Journal,2000,35(6):375-378.
Authors:WANG Jiang hua  XIE Li hua  LIU Hong yu  WANG Xuan  CAI Shao qin
Institution:Department of Pharmacognocy,Beijing Medical University,Beijing 100083
Abstract:OBJCTIVE To study the effects of different processing methods on the contents of active constituents in the Chinese traditional drug Xuanshen,Root of Scrophularia ningpoensis Hemsl.METHODS Using HPLC with harpagoside and cinnamic acid as standards.RESULTS The content of harpagoside in the slices of fresh roots dried in oven was higher than those in other processing products.There was also high content of harpagoside in the rhizome,bud and fibrous root materrials of S.ningpoenis ,but not found in the uerial parts.CONCLUSION To make slices with fresh roots and dry in oven may be a good processing method.Rhizome,bud and fibrous root can be used as the resources of harpagoside.
Keywords:Scrophularia ningpoensis  harpagoside  cinnamic acid  HPLC
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