无创正压通气治疗COPD急性加重期并Ⅱ型呼吸衰竭的效果观察

目的 探讨无创正压通气治疗慢性阻塞性肺疾病（COPD）急性加重期并Ⅱ型呼吸衰竭的临床效果.方法 选取本院2011年2月～2013年8月收治的90例COPD急性加重期并Ⅱ型呼吸衰竭,随机分为观察组和对照组,每组各45例.对照组患者给予常规的内科治疗,观察组患者在对照组的基础上加用无创正压通气治疗,比较两组患者治疗前、治疗3d和治疗7d的pH、PaO2、PaCO2、住院时间及死亡率.结果 观察组患者的住院时间明显短于对照组,死亡率明显低于对照组,两组间差异有统计学意义（P＜0.05）.经过治疗3、7d后两组各项指标均明显改善,观察组各指标与对照组比较,差异有统计学意义（P＜0.05）.结论 无创正压通气治疗COPD急性加重期并Ⅱ型呼吸衰竭的效果显著.

Effect observation of noninvasive positive pressure ventilation in the treatment of COPD exacerbations and H type of respiratory failure

Objective To explore the clinical effect of noninvasive positive pressure ventilation in the treatment of COPD exacerbations and II type of respiratory failure. Methods 90 patients with COPD exacerbations and II type of respiratory failure were selected in our hospital from February 2011 to August 2013,they were randomly divided into observation group and control group,45 cases in each group.The control group was given conventional medical treat- ment,the observation group was treated with noninvasive positive pressure ventilation on the basis of the control group, the pH,PaO2,PaCO2,1ength of hospital stay and mortality of two groups patients before treatment,treatment 3 d and 7 d were compared. Results The hospital time in observation group was significantly shorter than that of the control group, the mortality was significantly lower than that of the control group,the differences between the two groups was statisti- cally significant （P〈0.05）.All the indexes of two groups after treatment for 3 d,7 d were significantly improved,the index compared with the control group,the difference was statistically significant （P〈0.05）. Conclusion The noninvasive positive pressure ventilation treatment acute aggravating period of COPD and respiratory failure type lI effect is remarkable.