全文获取类型
收费全文 | 132530篇 |
免费 | 11230篇 |
国内免费 | 6934篇 |
专业分类
耳鼻咽喉 | 907篇 |
儿科学 | 2887篇 |
妇产科学 | 1663篇 |
基础医学 | 23977篇 |
口腔科学 | 2344篇 |
临床医学 | 9382篇 |
内科学 | 18278篇 |
皮肤病学 | 2407篇 |
神经病学 | 9816篇 |
特种医学 | 2326篇 |
外国民族医学 | 46篇 |
外科学 | 9057篇 |
综合类 | 21095篇 |
现状与发展 | 29篇 |
一般理论 | 1篇 |
预防医学 | 5902篇 |
眼科学 | 1880篇 |
药学 | 16519篇 |
12篇 | |
中国医学 | 3670篇 |
肿瘤学 | 18496篇 |
出版年
2024年 | 239篇 |
2023年 | 1796篇 |
2022年 | 3569篇 |
2021年 | 4775篇 |
2020年 | 3996篇 |
2019年 | 4207篇 |
2018年 | 3872篇 |
2017年 | 4043篇 |
2016年 | 4038篇 |
2015年 | 4770篇 |
2014年 | 6772篇 |
2013年 | 8162篇 |
2012年 | 6690篇 |
2011年 | 8225篇 |
2010年 | 6897篇 |
2009年 | 6877篇 |
2008年 | 7192篇 |
2007年 | 7336篇 |
2006年 | 6876篇 |
2005年 | 6315篇 |
2004年 | 5896篇 |
2003年 | 5238篇 |
2002年 | 4359篇 |
2001年 | 3833篇 |
2000年 | 3423篇 |
1999年 | 2838篇 |
1998年 | 2580篇 |
1997年 | 2224篇 |
1996年 | 1743篇 |
1995年 | 1525篇 |
1994年 | 1156篇 |
1993年 | 927篇 |
1992年 | 773篇 |
1991年 | 656篇 |
1990年 | 539篇 |
1989年 | 456篇 |
1988年 | 378篇 |
1987年 | 345篇 |
1986年 | 324篇 |
1985年 | 630篇 |
1984年 | 703篇 |
1983年 | 449篇 |
1982年 | 532篇 |
1981年 | 486篇 |
1980年 | 416篇 |
1979年 | 369篇 |
1978年 | 326篇 |
1977年 | 226篇 |
1976年 | 190篇 |
1975年 | 150篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
1.
2.
《Health & place》2022
PurposeAccording to the social determinants of health framework, income inequality is a potential risk factor for adverse mental health. However, few studies have explored the mechanisms suspected to mediate this relationship. The current study addresses this gap through a mediation analysis to determine if social support and community engagement act as mediators linking neighbourhood income inequality to maternal anxiety and depressive symptoms within a cohort of new mothers living in the City of Calgary, Canada.MethodsData collected at three years postpartum from mothers belonging to the All Our Families (AOF) cohort were used in the current study. Maternal data were collected between 2012 and 2015 and linked to neighbourhood socioeconomic data from the 2006 Canadian Census. Income inequality was measured using Gini coefficients derived from 2006 after-tax census data. Generalized structural equation models were used to quantify the associations between income inequality and mental health symptoms, and to assess the potential direct and indirect mediating effects of maternal social support and community engagement.ResultsIncome inequality was not significantly associated with higher depressive symptoms (β = 0.32, 95%CI = −0.067, 0.70), anxiety symptoms (β = 0.11, 95%CI = −0.39, 0.60), or lower social support. Income inequality was not associated with community engagement. For the depression models, higher social support was significantly associated with lower depressive symptoms (β = −0.13, 95%CI = −0.15, −0.097), while community engagement was not significantly associated with depressive symptoms (β = 0.059, 95%CI = −0.15, 0.27). Similarly, for the anxiety models, lower anxiety symptoms were significantly associated with higher levels of social support (β = −0.17, 95%CI = −0.20, −0.13) but not with higher levels of community engagement (β = 0.14, 95%CI = −0.14, 0.41).ConclusionThe current study did not find clear evidence for social support or community engagement mediating the relationship between neighbourhood income inequality and maternal mental health. Future investigations should employ a broader longitudinal approach to capture changes in income inequality, potential mediators, and mental health symptomatology over time. 相似文献
3.
Dongbing Lai Emma C. Johnson Sarah Colbert Gayathri Pandey Grace Chan Lance Bauer Meredith W. Francis Victor Hesselbrock Chella Kamarajan John Kramer Weipeng Kuang Sally Kuo Samuel Kuperman Yunlong Liu Vivia McCutcheon Zhiping Pang Martin H. Plawecki Marc Schuckit Jay Tischfield Leah Wetherill Yong Zang Howard J. Edenberg Bernice Porjesz Arpana Agrawal Tatiana Foroud 《Alcoholism, clinical and experimental research》2022,46(3):374-383
4.
《Cancer cell》2022,40(8):835-849.e8
- Download : Download high-res image (220KB)
- Download : Download full-size image
5.
目的探讨脊髓小脑共济失调2型(SCA2)致病基因ATXN2异常等位基因中间重复个体的表型和分子遗传学特点。方法针对2005—2018年中日友好医院神经科运动障碍与神经遗传病研究中心收集的1383个常染色体显性遗传共济失调家系的先证者和部分家系成员,采用荧光标记毛细管电泳片段分析方法进行动态突变检测,对携带ATXN2基因中间重复的个体进行临床表型和遗传特征分析。结果共检出163个家系(包含先证者和家系成员共203人)携带异常扩展的ATXN2基因CAG重复序列,其中93个家系中有107例的异常扩展等位基因重复次数在29~34次之间。在其中的20个亲子对中,父系遗传16个,异常等位基因的代间扩展增加0~28次,母系遗传4个,异常等位基因的代间扩展增加0~4次。结论对于临床拟诊SCA2家系患者,需对其亲代或成年子代个体进行ATXN2基因检测,以免漏诊。动态突变基因检测有助于识别中间重复的个体,对明确家系致病基因和遗传咨询至关重要。 相似文献
6.
7.
《Molecular therapy》2022,30(8):2856-2867
- Download : Download high-res image (173KB)
- Download : Download full-size image
8.
9.
《Research in social & administrative pharmacy》2022,18(9):3694-3698
In this paper, we argue that understanding and addressing the problem of poor-quality medical products requires a more interdisciplinary approach than has been evident to date. While prospective studies based on rigorous standardized methodologies are the gold standard for measuring the prevalence of poor-quality medical products and understanding their distribution nationally and internationally, they should be complemented by social science research to unpack the complex set of social, economic, and governance factors that underlie these patterns. In the following sections, we discuss specific examples of prospective quality surveys and of social science studies, highlighting the value of cross-sector partnerships in driving high-quality, policy-relevant research in this area. 相似文献
10.