排序方式: 共有33条查询结果,搜索用时 15 毫秒
1.
目的:介绍复方三棱胶囊的处方,制备及质量控制。方法:采用正交试验法优选了挥发油的提取,并利用β-环糊精包合技术达到了防止莪术挥发油挥发,增大水溶性,提高生物利用度的目的。结果:复方三棱胶囊的质量标准主要对性状,水分测定,装量差异,崩解时限等项目进行了研究,均符合《中国药典》一部(2005年版)的标准。结论:复方三棱胶囊处方合理,制备简单科学,质量可控。 相似文献
2.
3.
Ying Xiong Ke-Zhong Deng Yuan-Qiang Guo Wen-Yuan Gao Tie-Jun Zhang 《Archives of pharmacal research》2009,32(5):717-720
A new sucrose ester named β-D-(1-O-acetyl-3-O-cis-feruloyl)fructofuranosyl α-D-2′,3′,6′-O-triacetylglucopyranoside 1 and a novel phenylpropanoid glycerol named 1-O-cis-feruloyl-3-O-trans-p-coumaroylglycerol 2, have been isolated from Sparganium stoloniferum. Their structures were elucidated by spectroscopic methods. 相似文献
4.
中药三棱对多囊肾病囊肿衬里上皮细胞增殖及上皮生长因于受体磷酸化的影响 总被引:1,自引:0,他引:1
目的 探讨中药三棱对体外培养的常染色体显性遗传多囊肾病(ADPKD)囊肿衬里上皮细胞增殖及上皮生长因子受体(EGF-R)磷酸化的影响。方法 体外培养的囊肿衬里上皮细胞经EGF、三棱作用后,采用 Brdu掺入法测定细胞增殖,流式细胞仪测定细胞周期,Western blotting检测EGF-R磷酸化。结果 与对照组比较,EGF(2.5~20 ng/ml)可刺激衬里上皮细胞增殖(P<0.01);与对照血清比较,三棱含药血清(1%~5%)能明显抑制经EGF刺激后的衬里上皮细胞增殖(P<001),阻止细胞从G_0-G_1期进入G_2-M期,其作用效果呈浓度依赖性;三棱含药血清能抑制囊肿衬里上皮细胞EGF-R的磷酸化(P<0.05)。结论 EGF在多囊肾病发病中起促进作用,三棱可能通过对EGF-R磷酸化的干预而达到抑制细胞增殖的作用,从而为延缓多囊肾病的发生与发展提供理论根据。 相似文献
5.
It was reported that the ‘slow’ component (PsV-S) of Penicillium stoloniferum virus complex also occurred in a second genus, Aspergillus ochraceous. The responsible virus for this intergeneric occurrence was considered to be the ‘fast’ component (AoV-F) of A. ochraceous virus complex. In this investigation, AoV dsRNA 1, that was previously shown to cross-hybridize with PsV-S dsRNA, has been cloned. It was 1754 bp in length and contained one open reading frame of 539 amino acids (p63), had the same genome organization as PsV-S dsRNA S1 and also had the conserved sequence motif of the PsV-S dsRNAs (5′-GCGCAAAA-3′) at the 5′ terminus. A BLAST search indicated that p63 was a putative dsRNA-dependent RNA polymerase (RdRp), had 81% of sequence homology to members of the genus Partitivirus, and grouped together with PsV-S in phylogenetic analysis. But immunoblot analysis showed that the capsid protein (P3) of AoV-F virus component did not reacted against PsV-S antiserum. These evidences suggest that the cross serological relationship between AoV-F and PsV-S previously observed may have been due to the RdRps of the respective viruses rather than between their respective capsid proteins as was assumed in 1985. 相似文献
6.
7.
8.
9.
10.