诌议2004年美国SCI-Expanded收录中国大陆科技期刊

报道了2004年SCIE收录中国大陆科技期刊的情况，分析了期刊及论文被SCIE收录的意义，最后，就如何正确使用和看待SCI评价指标谈了作者的看法。     

大鼠脊髓损伤后NGF及其受体TrkA在运动神经元及神经胶质细胞表达的变化

为探讨脊髓损伤后运动神经元及神经胶质细胞内神经生长因子(NGF)及其高亲和力受体(TrkA)表达的变化,用改良Allen重击法损伤SCI组动物T12脊髓,按伤后存活时间再将动物分为脊髓损1 d组、2 d组和5 d组。各组动物的脊髓切片经ABC法免疫组织化学染色,用光镜观察TrkA及NGF在脊髓前角运动神经元表达的变化和胶质纤维酸性蛋白(GFAP)及NGF免疫反应阳性胶质细胞的反应性增生程度,并进行图像分析。结果显示:脊髓损伤后前角运动神经元TrkA及NGF的表达随脊髓损伤后动物存活时间的延长逐渐上调;脊髓白质和灰质内尤其是皮质脊髓束内GFAP及NGF阳性胶质细胞明显增生;与此同时,室管膜细胞内亦可见明显的NGF免疫反应产物。上述结果表明,脊髓损伤可刺激脊髓前角运动神经元表达TrkA及NGF,通过自分泌维持受损神经元的存活;损伤部位反应性增生的胶质细胞亦可产生NGF,通过旁分泌作用于脊髓前角运动神经元或皮质脊髓束的轴突末梢,以维持运动神经元的存活及促进皮质脊髓束的再生;适时补充外源性神经营养素或改变损伤局部的微环境将有利于受损脊髓的修复和再生。     

表没食子儿茶素没食子酸酯对脊髓损伤大鼠炎症因子释放及神经营养因子表达的影响

目的 :研究表没食子儿茶素没食子酸酯(epigaloctechin-3-gallit,EGCG)对脊髓损伤(spinal cord injury, SCI)大鼠炎症因子的释放及神经营养因子表达的影响。 方法 :建立大鼠脊髓半切SCI模型。SCI大鼠给予EGCG治疗24 h后取血清和受损伤脊髓局部组织。ELISA法测定血清白介素-6(IL-6)、白介素-8(IL-8)含量;Western blot法测定脊髓组织neurotrophin-3(NT-3)、brain-derived neurotrophic factor(BDNF)蛋白表达。 结果 :与模型组比较,EGCG能显著降低SCI大鼠血清炎性因子IL-6、IL-8的浓度,促进脊髓组织内源性NT-3、BDNF表达。 结论 :EGCG可抑制炎症因子释放,增加内源性神经营养因子表达。     

中外知名医科院校SCI收录论文统计分析与比较研究

被SCI收录论文的数量和质量是衡量高校基础研究水平、学术地位和办学质量的重要指标.本文对国内外30所知名医学院校2001-2005年被SCI收录的论文情况进行统计分析和比较研究,显示了国内外医科院校在科研规模、科研条件和科技水平方面存在的差距,并对如何提高我国医科院校被SCI收录论文的数量和质量提出了具体建议.     

Effect of the Affordable Care Act on healthcare utilization for Veterans with spinal cord injuries and disorders

Context/Objective: Provisions of the Affordable Care Act (ACA) potentially increase insurance options for Veterans with disabilities. We examined Veterans with spinal cord injuries and disorders (SCI/D) to assess whether the ACA was associated with changes in healthcare utilization from Department of Veterans Affairs (VA) healthcare facilities.Design: Using national VA data, we investigated impacts on VA healthcare utilization pre- (2012/13) and post-ACA (2014/15) implementation with negative binomial regression models.Setting: VA healthcare facilities.Participants: 8,591 VA users with SCI/D. Veterans with acute myelitis, Guillain-Barré syndrome, multiple sclerosis, or amyotrophic lateral sclerosis were excluded as were patients who died during the study period.Interventions: We assessed VA healthcare utilization before and after ACA implementation.Outcome Measures: Total numbers of VA visits for SCI/D care, diagnostic care, primary care, specialty care, and mental health care, and VA admissions.Results: The number of VA admissions was 7% higher in the post than pre-ACA implementation period (P < 0.01). The number of VA visits post-implementation increased for SCI/D care (8%; P < 0.01) and specialty care (12%; P < 0.001). Conversely, the number of mental health visits was 17% lower in the post-ACA period (P < 0.001). Veterans with SCI/D who live <5 miles from their nearest VA facility received VA care more frequently than those ≥40 miles from VA (P < 0.001).Conclusion: Counter to expectations, results suggest that Veterans with SCI/D sought more frequent VA care after ACA implementation, indicating Veterans with SCI/D continue to utilize the lifelong, comprehensive care provided at VA.     

基于ASP技术的SCI影响因子查询系统初探

SCI影响因子是评价科技论文和科技期刊水平的一个重要指标,及时方便地了解和查询SCI影响因子有助于科研人员分析科研绩效和衡量科技竞争力?文章利用动态服务器网页(ASP)的技术,构建了SCI影响因子查询系统,实现了有效?方便检索SCI影响因子的查询功能?     

SCI光盘相关文献的特点

对SCI相关文献的特点、检索功能等进行概述,指出利用相关文献这一特性对扩展检索功能、获得满意的检索结果有着明确的作用。     

Randomized Trial of Clitoral Vacuum Suction Versus Vibratory Stimulation in Neurogenic Female Orgasmic Dysfunction

Objective

To examine the safety and efficacy of using a clitoral vacuum suction device (CVSD) versus vibratory stimulation (V) to treat orgasmic dysfunction in women with multiple sclerosis (MS) or spinal cord injury (SCI).

Longitudinal Recovery and Reduced Costs After 120 Sessions of Locomotor Training for Motor Incomplete Spinal Cord Injury

Objective

To determine the impact of long-term, body weight–supported locomotor training after chronic, incomplete spinal cord injury (SCI), and to estimate the health care costs related to lost recovery potential and preventable secondary complications that may have occurred because of visit limits imposed by insurers.