生物羊膜贴敷治疗Ⅱ-Ⅲ度宫颈糜烂的临床观察

目的观察生物羊膜（以下简称羊膜）治疗Ⅱ～Ⅲ度宫颈糜烂的临床效果。方法将100例Ⅱ～Ⅲ度宫颈糜烂患者随机分为观察组和对照组各50例。观察组采用羊膜贴敷治疗,对照组采用局部微波治疗。观察2组临床疗效、阴道出血时间、排液时间及不良反应情况。结果观察组总有效率为100．0％高于对照组的86．0％,差异有统计学意义（P〈0．05）。治疗后观察组阴道出血时间、排液时间均短于对照组,差异有统计学意义（P〈0．01）。2组均未见明显不良反应。结论羊膜贴敷治疗宫颈糜烂效果显著,安全性好,预后无瘢痕,值得临床推广应用。     

复颈膏贴敷配合推拿治疗颈椎病90例临床观察

目的：观察复颈膏贴敷配合推拿治疗颈椎病的临床疗效。方法：将90例患者随机分为2组,治疗组60例,穴位及局部贴敷复颈膏,配合推拿。对照组给予氟桂利嗪并配合推拿。结果：治疗组总有效率100％,对照组90％;治疗组疗效明显优于对照组（P〈0．01）。结论：复颈膏配合推拿治疗颈椎病疗效较好。     

Acute Charles Bonnet syndrome secondary to eye patching

Objective

The aim of this study was to report a case of Charles Bonnet syndrome secondary to eye patching following eyelid reconstruction with an unusually acute onset.

Method

An observational case report was conducted.

Results

The patient reported complex visual hallucinations that started less than 10 minutes after patching of her right eye (the left eye had poor vision from previous trauma). The patch was removed after 2 days, and the hallucinations gradually stopped over the subsequent 2 days.

Conclusion

This case of Charles Bonnet syndrome describes an unusually acute onset of hallucinations and is only the second reported case following eye patching. Eye patching is commonly used in a number of situations, and it is important to be aware of this association, as the diagnosis of Charles Bonnet syndrome is often overlooked.     

Outcome of children with edge-everted traumatic tympanic membrane perforations following spontaneous healing versus fibroblast growth factor-containing gelfoam patching with or without edge repair

Objectives

To retrospectively analyze the outcome of children with edge-everted tympanic membrane (TM) perforations following spontaneous healing and fibroblast growth factor-containing gelfoam patching with or without repair of the edge flaps.

Methods

Medical records of children with TM perforations who underwent spontaneous healing (n = 69) or received fibroblast growth factor (FGF)-containing gelfoam patching treatment (n = 67) were retrieved from the Records Department of the Wenzhou Medical College-Affiliated Yiwu Hospital in China. The demographic data and outcome measures were analyzed and compared between these two groups of patients.

Results

Patching with FGF-containing gelfoams significantly improved the healing rate (P <0.01) and the average perforation closure time (P <0.01), as compared with spontaneous healing. Repair of the perforation edge flaps did not significantly affect the outcome of gelfoam patching (P > 0.05), despite a slightly reduced healing rate (96.4% versus 100%) and a slightly shorter closure time (10.2 ± 2.6 d versus 10.9 ± 3.3 d) observed as compared with no edge repair. The everted perforation edge flaps formed scabs during the process of spontaneous healing whereas they underwent retraction and eventually dissolved during the process of gelfoam patching-facilitated healing.

Conclusions

As compared with spontaneous healing, FGF-containing gelfoam patching had an improved outcome in children with edge-everted traumatic eardrum perforation. Repair of everted edge flaps did not affect the healing outcome. Our results suggest that growth factor-containing gelfoam patching without eardrum flap repair would offer a feasible option to manage traumatic tympanic membrane perforations in children.     

Monocular patching affects inattention but not perseveration in spatial neglect

Monocular patching might improve perceptual-attentional, not motor-intentional deficits in a patient with chronic post-stroke left spatial neglect. Performing a line-cancellation task, his omission errors were associated with a perceptual-attentional ‘where’ deficit, while perseverative errors were associated with ‘aiming’ motor-intentional bias. Contralesional patching had no effect on the omissions (p?=?.871), whereas ipsilesional patching reduced left-sided omissions compared with the unpatched condition (p?=?.016). Neither patching condition altered perseverative errors. Further research is needed to examine whether targeting treatments to spatial neglect symptoms (omissions, perseveration) results in improved outcomes.     

止痛散穴位贴敷联合柳氮磺吡啶治疗肾虚督寒强直性脊柱炎

[目的]观察止痛散穴位贴敷联合柳氮磺吡啶治疗肾虚督寒强直性脊柱炎疗效。[方法]使用随机平行对照方法,将144例住院患者按按病志号抽签简单随机分为两组。对照组72例柳氮磺吡啶片,第1周0.25g/次,2次/d,第2周0.5g/次,2次/d,第3周0.75g/次,2次/d,第4周以后1g/次,2次/d。治疗组72例止痛散穴位贴敷,穴位:大椎、命门、腰阳关、肺腧双侧、足三里双侧、外关双侧,1次/5d,连续3次;柳氮磺吡啶治疗同对照组。连续治疗12周为1疗程。观测临床症状、临床指标(BASFI指数、BASDAI指数、脊柱痛VAS评分、患者总体评分、CRP)不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈12例,显效34例,有效15例,无效8例,总有效率88.40%。对照组痊愈7例,显效16例,有效27例,无效20例,总有效率71.42%。治疗组疗效优于对照组(P0.01)。临床指标均有改善(P0.01,P0.05),治疗组优于对照组(P0.01)。[结论]止痛散穴位贴敷联合柳氮磺吡啶治疗肾虚督寒强直性脊柱炎,疗效显著,值得推广。     

三九贴敷治疗小儿痰湿蕴肺型咳嗽临床观察

目的：观察三九贴敷治疗小儿痰湿蕴肺型咳嗽的临床疗效。方法：在中国旧历节气＂三九＂将痰湿蕴肺型咳嗽患儿120人,随机分为3组观察临床症状及肺通气功能的改善情况。结果：贴敷同时服药有效率可达100%,与单纯贴敷组及单纯服药组差异均有显著性（P〈0.01,P〈0.05）;单纯贴敷组与单纯服药组差异有统计学意义（P〈0.05）。口服美普清同时辅助贴敷治疗与单纯口服美普清改善通气功能上有差异,但无统计学意义,口服美普清同时辅助贴敷治疗在改善通气功能上比单纯贴敷效果更加显著（P〈0.01）。结论：痰湿蕴肺型咳嗽发病期在口服药物的同时连续应用贴敷疗法,可辅助调节机体机能及改善肺通气功能而促进病情向愈,内外兼治可以缩短疗程,值得临床推广。     

不同遮盖时间治疗弱视的临床观察

目的 比较短时遮盖(4 h/d及6 h/d)和全天遮盖治疗3～7岁单眼弱视患儿的疗效.方法 对92例3～7岁单眼患儿进行准确的屈光矫正,均采用遮盖联合弱视训练的疗法,按遮盖时间差异随机分为每天遮盖健眼4h、6h和全天遮盖3组,余精细训练方法均相同,于治疗后第1个月和第6个月时对最佳矫正视力(BCVA)提升程度进行分析.结果 治疗1个月后,BCVA＜0.3者经全日遮盖后视力提升0.47±0.10,与4 h/d、6 h/d组间差异具有统计学意义(P＜0.05).BCVA ≥0.3者经3种不同遮盖时间治疗,3组间视力提升差异无统计学意义(P＞0.05),治疗6个月后,BCVA＜0.3者和BCVA≥0.3者经3种不同遮盖时间治疗,3组间视力提高差异均无明显差异(P＞0.05).结论 视力＜0.3的弱视患者在治疗初期采用全天遮盖疗法视力提升较快.在治疗后期,短时遮盖(4 h/d及6 h/d)与全天遮盖治疗弱视的疗效相似,但可提高患儿治疗依从性.