涉县26个村庄主要遗传病的调查

为了配合大学生暑期的社会实践活动,根据医学生所学知识,到涉县山区进行了主要遗传病的调查。在47000人口中进行普查,发现遗传病种12种,患者468例,其中单基因病19例,染色体病43例,多基因病369例;原因不明的疾病37例。人群中总的患病率(按调查人口数)为0.99％。患病率高的疾病主要有支气管哮喘,精神分裂症,原发性癫痫、先天愚、白癫疯等。     

涉县连翘生产标准操作规程(SOP)

通过对连翘生长发育过程探究和田间生产技术实践,制定适合于涉县连翘生产的标准操作规程。     

河北涉县更乐镇免费发放计生便民服务卡

河北省涉县更乐镇制作名片式＂计划生育便民服务卡＂,免费发放到育龄群众手中。 便民服务卡服务项目包括;办理新婚手册程序、办理一胎登记卡程序、办理二胎生育服务证程序、办理流动人口婚育证明程序等;设立了服务电话、监督电话以及24小时咨询热线。     

慢性炎症是贲门襄发生“始作俑者”

中国医学科学院肿癌医院的科研人员在我国食管癌、贲门癌高发区河北省涉县调查发现，贲门区的炎症与癌症的发生有密切关系；慢性活动性胃炎可能在贲门癌的发展过程中起重要作用．据调查，我国食管癌高发区贲门癌的发病率约为50／10万，食管癌与贲门癌之比约为6：4．因此，研究贲门癌前病变，对探索贲门癌在体内发生发展的规律具有重要意义。     

食管癌外科的治疗进展

中国是世界上食管癌病死率最高的国家,占世界病死率的46.6%(WHO 1997),食管癌总的5年生存率低于10%.在我国的食管癌高发区,其发病率和病死率均居各种恶性肿瘤的首位.随着人民生活水平的提高,防癌知识的普及和防癌措施的加强,在一些高发区,如河北涉县食管癌的病死率已由上世纪70年代的131.3/10万降至本世纪初的66.8/10万[1].     

NATURAL HISTORY OBSERVATION FOR ESOPHAGEAL AND CARDIA PRECURSORS BY REPETITIVE ENDOSCOPIC SCREENING OF 301 SUBJECTS IN SHEXIAN

OBJECTIVE To investigate the natural history of fast developing esophageal and cardia precursors. METHODS Repetitive endoscopic screenings were performed among 40-69-year-olds in the high-incidence areas for esophageal cancer in Shexian. RESULTS The initial diagnosis and the lag-time for 7 subsequently identified severe dysplasia （SD） subjects were as follows： in one subject 13 months after a baseline diagnosis of normal epithelium, in another subject 7 months after a baseline diagnosis of base cell hyperplasia （BCH）, in four subjects 3, 4, 4, and 10.5 months after baseline diagnosis of mild dysplasia （mD）, and in one subject 12.5 months after a baseline diagnosis of moderate dysplasia （MD）. The initial diagnosis and the lag-time for 6 subsequently identified carcinomas in situ or intramucosal carcinoma cases were： in one case 48 months after a baseline diagnosis of mD, in 2 cases 4 and 13 months after baseline diagnoses of MD, and in the other 3 cases 3.5, 9, and 17.5 months after baseline diagnoses of SD. The initial diagnosis and lag-time for 3 subsequently identified invasive cancer cases, were： in one case 50 months after a baseline diagnosis of MD, in 2 cases 14 and 19 months after baseline diagnoses of SD. In addition, during a 4-year-follow-up of 18 subjects after endoscopic mucosa resection, 9 of them were found to have developed precursors again at other sites, and also additional findings were obtained for 11 of the 16 dysplasia cases by repetitive biopsy in less than 2 months after the initial endoscopy. CONCLUSION A 5-year screening interval for BCH and mD, and a 3-year interval for MD may be too long for the fast developing precursors. Periodic screenings with shorter intervals should be considered to control the number of interval cases due to fast development, multifocal carcinogenesis, and false negative results inherent in one-time endoscopic biopsy sampling.     

2011年涉县人间布鲁氏菌病的监测报告

布鲁氏菌病(以下简称布病)是一种由布鲁氏菌引起的严重危害人民健康和畜牧业发展的人畜共患传染病,是<中华人民共和国传染病防治法>规定的乙类传染病.染疫的家畜是人间布病的主要传染源,人由于接触患病的牲畜及其产品或其污染物丽感染布病.布病不仅危害人体健康,同时影响畜牧业、旅游业、贸易及经济发展.