生物样品中氯胺酮的提取与检测方法技术新进展

目的综述各种生物检材中提取检测氯胺酮及其代谢物的方法。方法参考国内外相关文献,介绍了各生物检材特点,并列举了多种预处理和分析方法的优势与不足。结果由于氯胺酮的特殊药理作用,其娱乐性滥用现象较为严重和普遍,因此被列入新型毒品范畴。本文综述了几种快速、准确地检测出人体内氯胺酮及其代谢物的方法,并对各方法特点进行了总结概括。结论氯胺酮生物检材的提取检测方法正沿着更加方便、快速、准确的方向发展。     

胃食管反流病的中医证型研究纂要

胃食管反流病(GERD)迄今尚无相对应的中医病名和较为统一、规范、公认的中医辨证分型方法和标准。本文汇总了近15年关于胃食管反流病中医证型分类的相关文献,对胃食管反流病的中医证型、研究现状做一概述。结果提示胃食管反流病的病机以脾虚、气郁、痰湿、郁热为主,中医辨证分型以分五型之内为多。     

卵巢不敏感综合征的中西医研究进展

卵巢不敏感综合征(ROS)是以卵巢内有多量始基卵泡,少见窦状卵泡,无成熟卵泡为病理特征的综合征,临床主要表现为原发或继发闭经、内源性促性腺激素水平升高,染色体组型正常,卵巢对外源性促性腺激素刺激呈低反应。通过回顾近年现代医学对卵巢不敏感综合征的文献研究,对本病发病机制、病理、临床表现及诊断、中西医治疗方法予以综述。     

超声在流行性腮腺炎临床诊断中的研究进展

腮腺炎病毒传染会导致流行性腮腺炎爆发,属于一种急性的呼吸道疾病。临床症状主要表现为腮腺肿大、疼痛以及发烧,该病传染性极强,多见于儿童中流行爆发,而且该病一年四季都可以发病。本病在传播过程中,主要通过飞沫进行传播,在未经治疗的情况下该病在一周左右会自行消退,由于流行性腮腺炎是由病毒引起,目前并没有治疗该病的特效药物,只能依靠患者自身的免疫力。而儿童和青少年免疫系统正处在发育的过程中,如果不及时进行治疗,将会引发严重的并发症,只有尽早诊断和治疗,才能避免不良预后和大范围流行。     

医疗质量综合评价的综述

医务质量评价是医疗服务提供者和利用者都关心的问题。文章对我国国内医疗质量综合评价的概念、内容、对象、步骤和方法作了综述，对评价中存在的问题和对策进行了探讨。     

田振国教授治疗肛门瘙痒症经验

文章主要介绍著名肛肠专家田振国教授在治疗肛门瘙瘁症这一疾病方面的独到见解，并具体阐述肛门瘙瘁症的病因病机及田教授的辨证施治理念，内服与外用相结合，双管齐下的独到之处。     

中医解毒治法内科临床应用进展

解毒法是中医学独具特色的治疗方法。近年随着对疾病认识和研究的深入，其应用有了很大发展，特别是对许多难治危重性疾病有明显疗效，使这一传统治疗法则更加受到重视。现将目前在内科领域的部分应用进展情况简述如下。     

全国卫生监督机构人员现状研究课题概述与结果简介

《全国卫生监督机构人员现状研究》课题概述包括研究背景、目的、调查内容、样本收集方法和范围,以及主要结果。本研究于2010年6月至7月,对全国范围卫生监督机构进行了普查,旨在明确全国卫生监督机构工作人员的现状,进而发现存在的问题,为制定相应的人才队伍建设等策略提供参考。     

非手术治疗腰椎间盘突出症概况

90%的腰椎间盘突出症可通过非手术疗法得到缓解或治愈。非手术疗法包括牵引、推拿、针灸、中药内服热敷等。目前腰椎间盘突出症的治疗还应以保守治疗为主。临床多综合运用集中治疗方法,84%～90%的患者经过积极适当的非手术综合治疗都能取得良好效果。     

Trends in Incidence and Mortality Rates of Squamous Cell Carcinoma and Adenocarcinoma of Cervix - Worldwide

The objective of the present paper is to summarize and quantify the trends in incidence and mortality ratesof cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) worldwide. All indexed publications,which provided information on time trends in incidence or mortality rates of cervix cancer, published duringthe past 12 years were included. The details of studies have been identified through searches on the MEDLINEdatabase. Cytology screening as well as changes in socio-economic profile has led to declines in cervical SCCincidence and mortality rates worldwide. Higher percentage decline in SCC is observed in countries whereorganized screening programmes are available. The results suggested that Pap smear screening has played asignificant role in the reduction in SCC in the US, Canada, New South Wales, and in almost all Europeancountries (except in Ireland) as well as in some of the Asian countries. Increasing incidence and mortality ratesof cervical AC has reported in many countries such as the US, Canada, UK, Iceland, Sweden, England, Spain,Finland, Slovakia, Slovenia, the Netherlands particularly among young women. However the increase was mainlyin earlier periods till 1995 and stable or declining trends in cervical AC have been observed in later periods inmany of the above countries such as the US, UK, Canada, Sweden. The increasing risk of AC suggested a majorrole for an increasing prevalence of persistent oncogenic HPV infection and its cofactors, whereas the downturnin period effects in several countries during the 1990s provided evidence that cytology screening is detectingmore preinvasive ACs than in previous decades and suggested that screening might be starting to have a protectiveimpact on AC. The decline in AC incidence might be due to improved specimen collection as well as due toincreased awareness of AC pre-cursors among cytopathologists and clinicians, improvements in laboratorytraining and quality assurance. In conclusion, cytology screening in combination with HPV screening for highriskHPV types may maximize the possibilities of having early cervical lesions detected and treated.