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1.
目的:采用网状Meta分析方法,将普萘洛尔联合其他治疗与各对照治疗措施进行对比。方法:以“普萘洛尔”,“血管瘤”为关键词检索CNKI、VIP、万方数据;以“propranolol”“hemangioma”为关键词检索Cochrane Library、Embase、pubmed。检索期限为建库至2019年6月1日。采用STATA14.0软件Network程序包进行数据分析。结果:共纳入18篇文献,涉及8项治疗措施,共纳入1469例血管瘤患者。网状Meta分析结果显示:4种联合治疗方式与单纯口服普萘洛尔相比疗效均优于单纯口服普萘洛尔治疗。普萘洛尔联合注射平阳霉素、普萘洛尔联合外用噻吗洛尔、普萘洛尔联合敷贴器的有效率均优于对应的注射平阳霉素、外用噻吗洛尔及敷贴器。各治疗措施的有效性排序为:普萘洛尔联合敷贴器>普萘洛尔联合外用噻吗洛尔>普萘洛尔联合口服糖皮质激素>普萘洛尔联合注射平阳霉素>敷贴器照射>外用噻吗洛尔>口服普萘洛尔>注射平阳霉素。结论:对于婴幼儿血管瘤的治疗,普萘洛尔联合治疗措施疗效均优于单纯的口服普萘洛尔治疗,其中普萘洛尔联合敷贴器的疗效最佳。 相似文献
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Marie Ohata Susumu Fujiwara Ai Yoshioka Hiroshi Nagai Shintaro Sugita Nozomi Yamano Yusuke Inoue Chikako Nishigori 《Pediatric dermatology》2019,36(6):997-998
Fibroblastic connective tissue nevus (FCTN) is a benign cutaneous mesenchymal lesion characterized by proliferation of CD34‐positive fibroblastic/myofibroblastic spindle‐shaped cells. We report a case of agminated FCTN on the right lower abdomen of a 1‐year‐old boy. 相似文献
4.
BARI NUHOLU ALI AYYILDIZ VECIHI FIDAN ÖZDEN CEBECI UUR KOAR CANKON GERMIYANOLU 《International journal of urology》2006,13(2):109-110
OBJECTIVE: Nocturnal enuresis is a common pediatric problem, the etiology of which is unclear. In recent years, various studies have been published stating that children with nocturnal enuresis exhibit growth and skeletal maturation retardation. METHODS: In this cross-sectional study, we included 27 patients (16 boys, 11 girls) between the ages of 6 and 14 years who had presented with primary nocturnal enuresis (PNE) complaints. We included in the evaluation 19 healthy subjects (12 boys, 7 girls), who were the siblings of the children with PNE, as the control group. RESULTS: The patients in both groups were similar in chronological age, bone age, height and weight, with no significant difference between groups (P>0.05). CONCLUSION: The two groups in our study consisted of the same genetic background. Thus, our results were found to be different from the previous studies. We have concluded that there is no direct relationship between enuresis nocturnal and skeletal maturation. 相似文献
5.
AKIRA MATSUI YOICHI ARAKAWA TAKAYUKI MOMOYA NOBUHIKO SASAKI SEIJI KAWASAKI KOICHI TANAKA 《Pediatrics international》1996,38(6):699-701
Two infants with biliary atresia who exhibited three-fold increased trough levels of tacrolimus and required reduced doses during episodes of acute infantile diarrhea within 5 months of liver transplantation are described. The cause of the increase was not explained simply by hemoconcentration as a result of significant loss of extracellular fluid during these episodes. It does highlight an important issue: that of the continuing need to carefully monitor the trough levels of tacrolimus in such infants. 相似文献
6.
M. Mizuguchi H. Yamanouchi T. Ichiyama M. Shiomi 《Acta neurologica Scandinavica》2007,115(S186):45-56
Acute encephalopathy is the most serious complication of pediatric viral infections, such as influenza and exanthem subitum. It occurs worldwide, but is most prevalent in East Asia, and every year several hundreds of Japanese children are affected by influenza-associated encephalopathy. Mortality has recently declined, but is still high. Many survivors are left with motor and intellectual disabilities, and some with epilepsy. This article reviews various syndromes of acute encephalopathy by classifying them into three major categories. The first group caused by metabolic derangement consists of various inherited metabolic disorders and the classical Reye syndrome. Salicylate is a risk factor of the latter condition. The second group, characterized by a systemic cytokine storm and vasogenic brain edema, includes Reye-like syndrome, hemorrhagic shock and encephalopathy syndrome, and acute necrotizing encephalopathy. Non-steroidal anti-inflammatory drugs, such as diclofenac sodium and mephenamic acid, may aggravate these syndromes. Severe cases are complicated by multiple organ failure and disseminated intravascular coagulation. Mortality is high, although methylprednisolone pulse therapy may be beneficial in some cases. The third group, characterized by localized edema of the cerebral cortex, has recently been termed acute encephalopathy with febrile convulsive status epilepticus, and includes hemiconvulsion-hemiplegia syndrome and acute infantile encephalopathy predominantly affecting the frontal lobes. Theophylline is a risk factor of these syndromes. The pathogenesis is yet to be clarified, but an increasing body of evidence points to excitotoxicity and delayed neuronal death. 相似文献
7.
Shinichiro Yasumoto Jun Tsujita Shuhei Imayama Yoshiaki Hori 《The Journal of dermatology》1996,23(7):499-501
We report a case of Gianotti-Crosti syndrome associated with human herpesvirus-6 (HHV-6) infection. An eight-month-old girl developed monomorphous papules on her cheeks, buttocks, and extremities after the subsidence of exanthema subitum. Viral antibody analysis confirmed primary HHV-6 infection. HHV-6 may be added to the list of causative agents of Gianotti-Crosti syndrome. 相似文献
8.
Rose-Mary Boustany 《American journal of medical genetics. Part A》1992,42(4):533-535
My experience with more than 80 cases of the late infantile and juvenile forms of the neuronal ceroid-lipofuscinoses over the last 5 years has led to the following realizations. The 2 variants are neurologically distinct entities and probably are the result of different genetic defects. Treatment includes supportive measures and anticonvulsant medication. Therapy for behavioral and psychiatric disturbances in the juvenile type proves to be particularly challenging as neuroleptic medications tend to worsen parkinsonian like symptoms. Neuropathologic and neuro radiologic explanation of clinical symptomatology correlates best with neuronal loss and not neuronal storage. There is a paucity of neuropathologic documentation of these 2 types; additional reports are encouraged. 相似文献
9.
本文对28例小儿病毒性心肌炎患者进行了T细胞检测,发现患儿外周血T细胞亚群有明显改变。提示:小儿病毒性心肌炎患者均有不同程度的一过性细胞免疫功能低下。而体液免疫功能正常,我们在临床给与一般治疗的同时,佐以胸腺因子治疗,明显改善症状,取得良好疗效。 相似文献
10.
曾艺东 《白求恩军医学院学报》2005,3(3):137-138
目的观察喜炎平与维生素K3联合治疗小儿秋季腹泻的疗效.方法将89例秋季腹泻患儿随机分为2组.治疗组采用喜炎平与维生素K3联合治疗,对照组则采用利巴韦林治疗,疗程5d.结果治疗组的总有效率为93.3%,显著优于对照组的65.9%(X2=10.37,P<0.01).结论喜炎平与维生素K3联合治疗小儿秋季腹泻值得进一步推广. 相似文献