全文获取类型
收费全文 | 74篇 |
免费 | 1篇 |
国内免费 | 23篇 |
专业分类
基础医学 | 27篇 |
临床医学 | 3篇 |
内科学 | 1篇 |
皮肤病学 | 1篇 |
神经病学 | 1篇 |
特种医学 | 3篇 |
综合类 | 6篇 |
预防医学 | 22篇 |
药学 | 6篇 |
中国医学 | 5篇 |
肿瘤学 | 23篇 |
出版年
2023年 | 1篇 |
2022年 | 1篇 |
2021年 | 1篇 |
2019年 | 1篇 |
2018年 | 1篇 |
2016年 | 6篇 |
2015年 | 1篇 |
2013年 | 4篇 |
2012年 | 3篇 |
2011年 | 2篇 |
2010年 | 1篇 |
2009年 | 5篇 |
2008年 | 6篇 |
2007年 | 3篇 |
2006年 | 2篇 |
2005年 | 2篇 |
2004年 | 5篇 |
2003年 | 1篇 |
2002年 | 2篇 |
2001年 | 3篇 |
1999年 | 5篇 |
1998年 | 5篇 |
1997年 | 5篇 |
1996年 | 3篇 |
1995年 | 6篇 |
1994年 | 5篇 |
1993年 | 3篇 |
1992年 | 4篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1980年 | 1篇 |
1978年 | 1篇 |
排序方式: 共有98条查询结果,搜索用时 15 毫秒
1.
Peripheral blood mononuclear cells from patients with multiple myeloma, gastrointestinal tumors, and inflammatory bowel disease were analyzed for binding of various lectins. The results demonstrated that in most of the patients with multiple myeloma a significantly increased percentage of cells positive for Lotus tetragonolobus agglutinin (LTA), peanut agglutinin (PNA), soybean agglutinin (SBA), and wheat germ agglutinin (WGA), and a decreased number of Agaricus bisporus agglutinin (ABA) positive cells were present as compared to a normal control group. This could not be shown in malignant or inflammatory disorders of the gastrointestinal tract where only some patients exhibited an increased PNA and LTA binding, respectively. Patients with the systemic malignant disease differed from patients with solid localized tumors by a significantly altered number of ABA, LTA and SBA-positive peripheral blood mononuclear cells. Double fluorescence studies using monoclonal antibodies and lectins revealed that most of the cells expressing receptors for ABA had also receptors for OKT3, whereas most of the cells with receptors for LTA, PNA SBA, and WGA were found to be positive for OKM. 相似文献
2.
Preparations of double-stranded (ds) RNAs extracted from naturally infected Vicia faba Linn. growing in Hangzhou, Zhejiang Province, Eastern China displayed 3 dominant bands (FaR1, FaR2, and FaR3). FaR2 and FaR3
were found to be identical to the genomic dsRNAs of a recently reported Vicia cryptic virus (VCV). The positive strand of
FaR1 contained two large open reading frames (ORFs), ORF1 and ORF2. The putative proteins encoded by these ORFs were found
to have certain similarities to the putative capsid protein [ABO36237] and RNA-dependent RNA polymerase [ABC96788], respectively,
of Tomato yellow stunt virus. Thus, FaR1 may represent the genome of a new dsRNA virus, which we have named Vicia cryptic
virus M.
The GenBank Accession numbers of the sequences reported in this paper are EU605883, EU605884, and EU371896. 相似文献
3.
4.
The contamination of surface- and groundwater by the leaching of solid wastes generated by industrial activities as a result of water runoff and rainfall is a matter of great concern. The leachates from tannery solid waste (TSW), a major environmental pollutant, were examined for their possible genotoxic effects on the somatic cells of Vicia faba. Leachates were prepared from solid wastes procured from leather-tanning industrial sites, and V. faba seedlings were exposed to three test concentrations, 2.5%, 5%, and 10%, through soil and aqueous media for 5 days. The root tips examined for cytogenetic damage revealed that leachate of TSW significantly inhibited the mitotic index and induced significantly frequent chromosomal and mitotic aberrations (CA/MA) in a dose-dependent manner. The chemical analysis of TSW samples revealed that the chief constituents were chromium and nickel, which may cause genetic abnormalities. The frequency of aberrations was found to be higher in the root meristematic cells of Vicia faba exposed through the aqueous medium than those exposed through the soil medium. The results of the present study indicated that contamination of potable water bodies by leachates of TSW may cause genotoxicity. For the biomonitoring of complex mixtures of toxicants with the V. faba bioassay, the use of the aqueous medium seems to be a more promising method than the use of the soil medium. 相似文献
5.
《环境与健康杂志》2009,26(7)
目的 探讨水环境中汞、镉、砷、六价铬及铅对蚕豆根尖细胞的诱变作用.方法 通过蚕豆根尖细胞微核试验以汞(0.000 5~1.0mg/L)、镉(0.005~1.0mg/L)、砷(0.05~2.0mg/L)、六价铬(0.05~2.0mg/L)及铅(0.05~3.0mg/L)为诱变剂,测定蚕豆根尖细胞的微核率并计算污染指数.结果 汞(0.000 5~0.1 mg/L)、镉(0.005~0.05 mg/L)、砷(0.05~0.1 mg/L)、六价铬(0.05~0.1 mg/L)及铅(0.05~0.1 mg/L)染毒后微核率高于阴性对照组,但差异无统计学意义(P>0.05).水中汞浓度≥0.5 mg/L、镉浓度≥0.1 mg/L、砷浓度≥0.5 mg/L、六价铬浓度≥2.0 mg/L时的微核率高于阴性对照组,差异有统计学意义(P<0.05,P<0.01),污染指数在1.5~2.4之间.结论 汞、镉、砷、六价铬对蚕豆根尖细胞具有一定的遗传毒性. 相似文献
6.
7.
本文应用蚕豆根尖细胞微核试验分析了S市饮用水的致突性。水样采自S市12个区(县)居民点末梢自来水共13份,同时以双蒸水为对照水样。结果表明,两种蚕豆根尖细胞分别经末梢自来水处理6小时后,其诱发的微核率,除3份水样的微核率接近本底值外,其余水样均有一定程度的升高。6份水样属基本无致突物污染,5份水样属污染,仅2份水样达中度污染。不同水样诱发微核率差别的原因是水质,因同一水厂供水范围内的水样,其诱发的微核率属同一污染程度。同时测定总有机碳(TOC)含量的结果也表明,微核率的高低与TOC含量高低一致。本实验提示蚕豆根尖细胞微核试验可用于即位评价环境污染。 相似文献
8.
射频辐射对蚕豆根尖细胞微核率影响的研究 总被引:1,自引:0,他引:1
利用蚕豆根尖细胞微核试验对射频辐射污染引起的生物染色体突变效应进行了实验室观察和现场监测。实验室观察结果表明,微波辐射可致蚕豆根尖细胞微校率升高,辐射剂量在5~20mW/cm2范围内,细胞微核率随辐射剂量的增加而升高,当辐射剂量在20mW/cm2以上时,微核率与辐射剂量不再呈线性关系,但仍高于阴性照组(P<0.01)。以实验室结果为依据进行的现场监测结果显示,蚕豆根尖细胞微校率随现场场强的增强而升高,有很好的剂量效应关系(r=0.9769.P<0.01)。提示,射频辐射对蚕豆根尖细胞有明显的致突变作用,并且蚕豆根尖细胞微核试验可用于环境射频辐射污染的监测。 相似文献
9.
10.
Three seed sources of lectins which are of potential value in the classification of red cell polyagglutinability are described. 相似文献