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排序方式: 共有3311条查询结果,搜索用时 15 毫秒
1.
松龄血脉康抑制肺动脉高压的实验研究 总被引:1,自引:0,他引:1
为观察松龄血脉康胶囊对肺动脉高压大鼠肺动脉压的影响,取100只健康Wistar大鼠,其中60只背部注射野百合碱monocrotaline,MCT80mg/kg复制出肺动脉高压模型。再将其分为两组,各30只,其中一组以标准饲料喂养,另一组加用松龄血脉康胶囊1.5g·kg-1·d-1。其余40只健康大鼠做为正常对照组,在实验当天、7天、14天、21天、28天、35天从各组中随机抽取5只行右心导管测肺动脉压。结果:注射MCT后肺高压组28天时达高峰,但加用松龄血脉康组上升幅度明显小于未用药组。结论:松龄血脉康有显著抑制大鼠肺动脉高压发展的作用 相似文献
2.
Philip Darbyshire 《Nursing inquiry》1995,2(4):198-202
Reclaiming 'Big Nurse': a feminist critique of Ken Kesey's portrayal of Nurse Ratched in One Flew Over the Cuckoo's Nest Nurse Ratched or 'Big Nurse' in Ken Kesey's counter-culture novel One Flew Over the Cuckoo's Nest is one of popular culture's most arresting and memorable images of the nurse. She is, however, deemed to be remarkable primarily for her malice and authoritarianism. This paper argues that such a purely realist reading fails to fully appreciate the significance of the character of Nurse Ratched. A feminist critique of the novel contends that die importance of 'Big Nurse' is less related to how realistic/unrealistic or good/bad she is as a nurse. Nurse Ratched is important because she exemplifies all diat traditional masculinity abhors in women, and particularly in strong women in positions of power and influence. This paper explores the stereotype of 'Big Nurse' and argues that Kesey's vision of her ultimate 'conquest' is not a progressive allegory of 'individual freedom', but a reactionary misogyny which would deny women any function other than that of sexual trophy. 相似文献
3.
A microcapsule form of nitrofurantoin was prepared by a simple coacervation method with carboxymethylcellulose and aluminium sulfate. 33 factorial design was performed for three independent variables, namely, the particle size of the drug, the size of the microcapsules and the pH of the dissolution medium. The dissolution tests with the formulated microcapsules were carried out according to the United States Pharmacopeia XXII rotating basket method at pH 1.2, 5 and 7.5, which represent the pH of gastrointestinal fluids. Release data were examined kinetically and the ideal kinetic models were estimated and t
63.2 values obtained from RRSBW distribution were used in the factorial design experiment. The influence of the independent variables on the dissolution of nitrofurantoin microcapsules could be expressed as the pH of the dissolution medium > particle size of the microcapsule > particle size of nitrofurantoin. The other aim of this study was to evaluate microcapsule formulation in terms of the United States Pharmacopeia criteria with a minimum of experiments. Our findings suggest that dosage forms which comply with the pharmacopoeia criteria for dissolution can be prepared and selected by factorial design. 相似文献
4.
C57BL/6J (B6) and DBA/2J (D2) mice differ in maternal behavior and nest building, but previous observations on nest building appear to be contradictory. Lactating B6 females spent more time nest building than lactating D2 females [Physiol. Behav. 67 (1999) 599.]; however, pregnant D2 females have been reported to build better nests than pregnant B6 females [Physiol. Behav. 29 (1982) 153.]. To resolve this apparent discrepancy, virgin B6 and D2 females were mated, and the nest quality of nulligravid, primigravid and lactating primiparous females was compared between groups and with that of virgin females. There were no strain differences in the nest ratings of virgin or mated nulligravid females, nor did these groups differ within strains. Pregnant and lactating females of both strains built better nests than nonpregnant females. There was an increase in nest ratings in both strains on the day of parturition. The nest ratings of pregnant and lactating females were higher in B6 than D2 females. The largest strain differences were observed between pregnant B6 and D2 females. One hypothesis to account for these results is that females of these two strains differ in their levels of or sensitivity to hormones during pregnancy and parturition. 相似文献
5.
目的 探讨灵宝护心丹联合参松养心胶囊治疗窦性心动过缓的临床疗效。方法 选取2019年3月—2020年12月抚州市中医医院内科诊断为窦性心动过缓患者100例,随机分为对照组(50例)和治疗组(50例)。对照组给予参松养心胶囊(每天3次,每次4粒),治疗组在对照组的基础上给予灵宝护心丹(每天3次,每次4粒),治疗24周。治疗后比较两组的临床疗效、24 h动态心电图指标、心率变异性时域指标及不良反应。结果 治疗组中医证候有效率84.0%,对照组为60.0%,两组比较差异有统计学意义(P<0.05)。治疗组动态心电图总有效率86.0%,对照组64.0%,两组比较差异有统计学意义(P<0.05)。治疗后,两组平均心率、总心率、最快心率、最慢心率、24 h全部正常心室搏动间距(R wave-R wave,R-R)间期标准差(standard diviation of NN intervals,SDNN)、24 h连续5 min节段正常R-R间期的标准差(standard deviation of sequential five-minute R-R interval means,SDA... 相似文献
6.
反相高效液相色谱法测定双黄连胶囊中绿原酸的含量 总被引:3,自引:0,他引:3
目的 :建立中成药双黄连胶囊中绿原酸的含量测定方法。方法 :采用Phenomenex -C1 8(2 5 0mm×4 6mm ,5 μm)柱 ,以水 -乙腈 -冰醋酸 (92∶7∶1 0 )为流动相 ,检测波长 32 6nm ,流速 1 0ml/min。结果 :绿原酸在 0 1 1~ 0 5 5 μg ,都与相应的峰面积呈良好的线性关系 (r=0 9999) ,平均回收率为 99 1 1 % ,RSD为 0 5 8% (n =6 )。结论 :该方法准确可靠 ,可用于双黄连胶囊制剂的质量控制 相似文献
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9.
葛根素治疗颈性眩晕临床观察 总被引:8,自引:0,他引:8
以葛根素加半夏白术天麻汤治疗颈性眩晕45例,为治疗组;以西北灵加半夏白术天麻汤治疗42例,为对照组。通过两组临床疗效观察:治疗组显效27例,有效16例,无效2例,有效率为96.0%;对照组显效8例,有效24例,无效10例,有效率为77.0%,对比有显著性差异(P<0.01)。 相似文献
10.
薄层扫描法测定维参锌胶囊中人参皂苷Re的含量 总被引:1,自引:0,他引:1
目的 用薄层扫描法测定维参锌胶囊中人参皂苷Re的含量。方法 以氯仿-甲醇-水(65:35:10)为展开剂,双波长反射法锯齿扫描:λs=525nm,λR=700nm。结果 平均回收率为98.80%,RSD =0.67%(n =5)。结论 该方法简便、准确、重现好。 相似文献