全文获取类型
收费全文 | 2082篇 |
免费 | 172篇 |
国内免费 | 84篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 7篇 |
妇产科学 | 12篇 |
基础医学 | 40篇 |
口腔科学 | 21篇 |
临床医学 | 206篇 |
内科学 | 42篇 |
皮肤病学 | 7篇 |
神经病学 | 32篇 |
特种医学 | 23篇 |
外科学 | 165篇 |
综合类 | 351篇 |
预防医学 | 62篇 |
眼科学 | 2篇 |
药学 | 874篇 |
1篇 | |
中国医学 | 463篇 |
肿瘤学 | 26篇 |
出版年
2024年 | 11篇 |
2023年 | 20篇 |
2022年 | 33篇 |
2021年 | 58篇 |
2020年 | 65篇 |
2019年 | 44篇 |
2018年 | 67篇 |
2017年 | 65篇 |
2016年 | 79篇 |
2015年 | 62篇 |
2014年 | 132篇 |
2013年 | 160篇 |
2012年 | 155篇 |
2011年 | 146篇 |
2010年 | 93篇 |
2009年 | 89篇 |
2008年 | 95篇 |
2007年 | 98篇 |
2006年 | 62篇 |
2005年 | 79篇 |
2004年 | 71篇 |
2003年 | 67篇 |
2002年 | 66篇 |
2001年 | 50篇 |
2000年 | 45篇 |
1999年 | 43篇 |
1998年 | 33篇 |
1997年 | 35篇 |
1996年 | 29篇 |
1995年 | 26篇 |
1994年 | 16篇 |
1993年 | 27篇 |
1992年 | 17篇 |
1991年 | 18篇 |
1990年 | 12篇 |
1989年 | 12篇 |
1988年 | 15篇 |
1987年 | 8篇 |
1986年 | 10篇 |
1985年 | 14篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1982年 | 15篇 |
1981年 | 14篇 |
1980年 | 14篇 |
1978年 | 7篇 |
1977年 | 6篇 |
1976年 | 13篇 |
1974年 | 8篇 |
1973年 | 6篇 |
排序方式: 共有2338条查询结果,搜索用时 31 毫秒
1.
自控止痛泵在疼痛治疗中的应用 总被引:1,自引:0,他引:1
介绍了自控止痛泵在临床各种类型疼痛病人治疗中的应用 ,研究了最佳给药途径、注药模式及常见的不良反应 ,为临床正确用药提供了帮助。 相似文献
3.
R S Nanra 《Nephrology, dialysis, transplantation》1992,7(5):384-390
Comprehensive renal function tests were performed in 84 patients with analgesic nephropathy, 33 glomerulonephritis patients matched for creatinine clearance, and 30 control subjects. A system of 1-day renal function tests including urine microscopy, creatinine clearance, phenolsulphonphthalein excretion, urine concentration and acidification, and electrolyte excretion, was used. Patients with analgesic nephropathy were found to have significant sterile pyuria and haematuria, even those with mild renal insufficiency, significantly reduced concentrating ability and a distal acidifying defect, and a tendency to impaired sodium conservation. These function defects are consistent with the primary lesion of renal papillary necrosis in analgesic nephropathy; the detection of these defects have implications in patient management. 相似文献
4.
乳舒胶囊镇痛、抗炎作用研究 总被引:2,自引:0,他引:2
目的:研究乳舒胶囊(RS)的镇痛、抗炎药效。方法:采用RS灌胃给药后,分别用甩尾法、热板法、扭体法研究RS对乳腺增生模型大鼠及小鼠的镇痛作用,分别用二甲苯法、琼脂法研究RS抑制小鼠耳廓炎症及大鼠慢性炎症性肉芽肿的作用。结果:乳舒胶囊能提高乳腺增生模型大鼠和小鼠的痛阈值、能减少醋酸致扭体疼痛小鼠的扭体次数、延长其发生扭体的潜伏期,有明显的镇痛作用;还可以抑制琼脂所致的大鼠肉芽肿和二甲苯致小鼠耳肿胀,有明显的抗炎作用。结论:乳舒胶囊镇痛、抗炎作用明显、疗效确切。 相似文献
5.
István Pintér János Mátyus Zoltán Czégány Judit Harsányi Marietta Homoki Miklós Kassai Eva Kiss István Kiss Erzsébet Ladányi Lajos Locsey Lajos Major Mihály Misz Lajos Nagy Kálmán Polner Jeno Rédl István Solt Béla Tichy Marietta T?r?k Gábor Varga Gyula Wagner Imre Wórum Béla Zsoldos László Pótó Katalin Dérczy István Wittmann Judit Nagy 《Nephrology, dialysis, transplantation》2004,19(4):840-843
BACKGROUND: The diagnosis of analgesic nephropathy has improved significantly with modern imaging techniques. We reviewed a large portion of the Hungarian dialysis population to obtain additional insight into the problem. METHODS: Twenty-two participating dialysis units enrolled 1400 patients on renal replacement therapy between 1 January 1995 and 1 January 1998. Patients with no known aetiology (n = 284) were interviewed and studied with renal imaging. We assessed the presence of decreased renal mass combined with either bumpy contours, papillary calcification, or both. The subjects studied were interrogated extensively. RESULTS: Our survey suggested analgesic nephropathy in 47 of 1400 patients (3.3%), 3-fold higher than the EDTA database estimate for Hungary. The analgesics most commonly abused were phenacetin-containing mixtures. The driving symptoms were mainly headache and joint pain. Cardiovascular complications were more common than in the rest of the dialysis population, independent of smoking and lipid values (P<0.01). CONCLUSIONS: Phenacetin should be banned. Our study results support the need for longitudinal cohort and case-control studies in Hungary. 相似文献
6.
7.
钾离子通道的活性状态对蛛网膜下腔注射腺苷抗伤害性作用的影响 总被引:1,自引:0,他引:1
目的探讨ATP敏感型钾离子通道的活性状态对鞘内注射腺苷类似物R-phenylisopropyladenosine(R-PIA)抗伤害性作用的影响.方法雄性SD大鼠在苯巴比妥钠麻醉下,蛛网膜下腔留置PE-10导管,测定注药后鼠尾对光热刺激的反应(抗伤害作用).结果蛛网膜下腔注射R-PIA产生剂量依赖性的甩尾时间曲线上移(P<0.05).蛛网膜下腔注药后10min起效,镇痛时间长达60min.ATP敏感型通道开放剂nicorandil和阻滞剂glibenclamide单独蛛网膜下腔应用无镇痛作用(P>0.05),但nicorandil明显增强R-PIA的抗伤害性作用,相反glibenclamide明显减弱R-PIA的抗伤害性作用(P<0.05).结论蛛网膜下腔注射R-PIA可产生明显的剂量依赖性抗伤害作用,此作用受ATP敏感型钾离子通道活性调节. 相似文献
8.
M. Ahmad Agil S. Risco M. Mir M. C. Navarro M. A. Ocete J. Jimnez 《Phytotherapy research : PTR》1995,9(2):135-138
The dried (elaterium) or fresh juice from Ecballium elaterium fruit is used in the treatment of various inflammatory conditions in popular medicine. In this study the elaterium is examined for its analgesic and antipyretic effects in several animal models. The elaterium exhibits both analgesic and antipyretic activities. 相似文献
9.
辽宁产东亚钳蝎毒的镇痛作用——离体海马脑片的细胞内电位记录 总被引:1,自引:0,他引:1
应用离体脑片技术及细胞内生物电记录方法,研究辽宁产东亚钳蝎毒及某些活性物质对海马CA1区痛敏神经元的影响,以了解蝎毒的作用机制,在海马CA1区记录到细胞内放电54个单位,其静息电位平均值为45±5mV,当给予海马伞入口处一定强度刺激时,在海马CA1区记录到细胞内放电,向海马脑片灌注蝎毒液时,CA1区细胞内放电受抑制,说明蝎毒液有镇痛作用 相似文献
10.
Twenty-six infants due to undergo major abdominal or thoracic surgery under general anaesthesia were randomized to receive additional analgesia with group A) spinal/epidural analgesia; B) epidural analgesia or C) opioid analgesia with fentanyl. We wished to determine if spinal analgesia followed by epidural analgesia might result in more complete control of cardiovascular or stress responses than the other two treatment groups. Heart rate and blood pressure were recorded at five min intervals throughout surgery. Blood samples were taken for measurement of catecholamines and whole blood sugar on induction, 45 min after skin incision and at the end of surgery. Heart rate rose significantly at the start of surgery in groups B and C but not group A. Systolic blood pressures were higher in group C compared to A and B. The rise in plasma glucose concentrations was significantly different between the groups in the order C>B>A (P<0·05). A similar trend was seen in the plasma adrenaline and noradrenaline concentrations but this failed to achieve significance due to the limited sample size. 相似文献