常见植物药对结肠癌的防治作用及其作用机制

植物药对结肠癌具有良好的防治作用。姜黄素、多糖(苹果多糖、香菇多糖)、皂苷(重楼皂苷、人参皂苷)、白藜芦醇、槲皮素等植物药可通过不同信号通路抑制结肠癌细胞的增殖,促进细胞凋亡。此外,植物药还具有抗炎、抗氧化、抗血管生成、减轻化疗药物不良反应、逆转肿瘤细胞耐药等作用。了解植物药对结肠癌的防治作用及其可能的作用机制,能为结肠癌的临床防治提供更多的理论依据及治疗思路。     

Pregnant women’s use and attitude toward herbal,vitamin, and mineral supplements in an academic tertiary care center,Riyadh, Saudi Arabia

Background

Herbal medicine has been widely utilized by pregnant women despite the limited available evidence regarding the safety and efficacy of that practice. The current available studies, from different countries, estimated that the use of herbal medicine during pregnancy range from 7% up to 96%. The aim of this study is to determine the prevalence, attitude, source of information, and reasoning behind the use of herbal medicine among pregnant women in Saudia Arabia.

Bleeding complications precipitated by unrecognized Gingko biloba use after liver transplantation

Because of its neurocognitive enhancing effects, Gingko biloba has emerged as amongst the most commonly used herbal products. We report a liver transplant recipient with potentially life-threatening toxicity resulting from Gingko biloba use. Seven days after a second liver transplantation for recurrent hepatitisB virus infection, subphrenic hematoma was documented in a 59-year-old Korean patient. Failure to control bleeding with CT-guided drainage necessitated exploratory laparotomy for the evacuation of a large subphrenic hematoma. Three weeks later, an episode of vitreous hemorrhage was documented. Unbeknownst to his care providers, the patient had been consuming Gingko biloba throughout the postoperative period. No further bleeding episodes occurred after the cessation of Gingko biloba use. Unrecognized use of herbal products may be associated with serious side effects and adverse clinical sequelae in transplant recipients. Given their increasing popularity, the use of herbal products should be routinely sought as part of the history in transplant recipients.     

中药高臀位灌肠治疗慢性肾功能衰竭疗效观察

目的 观察中药高臀位灌肠治疗慢性肾功能衰竭(chronic renal failure,CRF)的临床疗效.方法 将100例CRF患者随机分为两组,治疗组70例采用中药高臀化灌肠治疗,对照组30例口服活性炭治疗.结果 治疗组总有效率为88.6%,对照组总有效率为50.0%.结论 中药高臀位灌肠治疗CRF有效.     

The Rise of a New Psychoactive Agent: Salvia divinorum

Since the 1990s, there has been a rise in the availability and recreational use of a herbal plant called Salvia divinorum. Numerous internet websites have advertised it for sale as a legal herbal alternative to illegal hallucinogens. Initial data surveying use has indicated many young adults are obtaining and using this herb for its psychoactive properties. Reported methods of ingestion for the plant include chewing, and smoking leaves or fortified extracts. Subjective effects of the plant include, affect changes, psychedelic-like changes in perception, and even loss of consciousness. Although the pharmacological properties and possible antidepressant effects have been studied in recent years, little information is known about potential negative impact resulting from recreational use, and scant information about Salvia divinorum currently exists in the psychological and substance abuse literature. While Salvia divinorum appears to be a substance with some therapeutic potential, it also poses some significant dangers as a substance of varying legal status with a potential for abuse.     

综合矫正训练方案联合中药熏蒸治疗上交叉综合征疗效观察

<正>上交叉综合征(upper crossed syndrome,UCS)是指因上半身长期处于不良姿势,造成相关肌群功能失衡,进而引起颈肩背部疼痛不适、胸闷、睡眠障碍等一系列不良症状的一种亚健康状态^[1]。UCS常见的体态是圆肩、驼背、头前倾^[2]。目前临床上主要通过纠正局部的肌肉失衡来治疗UCS,常用的方法有运动疗法、肌肉能量技术、针灸和推拿等^[3]。     

熏眼与按摩治疗干眼症的持续护理改进对策

目的探讨熏眼与按摩治疗干眼症的持续护理改进对策。方法选择2018年6月—2019年6月于我院接受中药熏眼与睑板腺按摩治疗的干眼症患者196例,以随机数字表法将其随机分为两组,其中对照组与研究组各98例。对照组患者接受常规护理,研究组在此基础上应用持续护理改进对策。评价两组患者的治疗效果、干眼症的复发情况,以及护理满意度。结果研究组治疗的总有效率为97.96%高于对照组90.80%(P<0.05)。研究组复发率3.06%低于对照组12.24%(P<0.05)。研究组护理满意率98.98%高于对照组90.82%(P<0.05)。结论持续护理改进对策能够保证熏眼与按摩治疗干眼症的效果,抑制疾病复发,并增强了患者对护理服务的满意度。     

复方柴胡汤加减对大鼠酒精性肝损伤形态学和线粒体的定量研究

目的：探讨中药复方对酒精性肝损伤的防护作用。方法：形态学观察（光镜,电镜）应用MPIAS－500病理图文分析系统做线粒体定量分析（面积,周长,等效直径,平均光密度）,结果：光镜损伤组肝细胞破坏明显,呈气球样变,有酒精小体,汇管区有炎细胞浸润,而防治组与正常组相似,肝小叶排列规则,细胞体积大,分界清晰,电镜损伤组细胞不规则,胞质疏松,含大量脂滴,而防治组与正常组相似,核大而规则,含丰富的细胞器,无或少量脂滴,线粒体各指标损伤组与防治组差异显著（P＜0．01）。结论：本中药复方对酒精性肝损伤具有一定的防护作用。     

Reversible hepatic veno-occlusive disease in an infant after consumption of pyrrolizidine-containing herbal tea

Veno-occlusive disease was diagnosed in an 18-month-old boy who had regularly consumed a herbal tea mixture since the 3rd month of life. The boy developed portal hypertension with severe ascites. Histology of the liver showed centrilobular sinusoidal congestion with perivenular bleeding and parenchymal necrosis without cirrhosis. The tea contained peppermint and what the mother thought was coltsfoot (Tussilago farfara). The parents believed the tea aided the healthy development of their child. Pharmacological analysis of the tea compounds revealed high amounts of pyrrolizidine alkaloids. Seneciphylline and the corresponding N-oxide were identified as the major components by thin-layer chromatography, mass spectrometry and NMR spectroscopy. We calculated that the child had consumed at least 60 g/kg body weight per day of the toxic pyrrolizidine alkaloid mixture over 15 months. Macroscopic and microscopic analysis of the leaf material indicated thatAdenostyles alliariae (Alpendost) had been erroneously gathered by the parents in place of coltsfoot. The two plants can easily be confused especially after the flowering period. The child was given conservative treatment only and recovered completely within 2 months.