四元胶乳互穿聚合物网络的组成对其性能的影响

用分步乳液聚合法合成了具有核壳结构的胶乳互穿聚合物网络ＬＩＰＮ（ＰＭＭＡ－ＰＳ）／（Ｐｎ－ＢＡ－ＰＡＡ）；讨论了ＬＩＰＮ组成对乳液与膜性能的影响，提出了四元ＬＩＰＮ核壳结构的基本轮廓，探讨了软硬单体最佳配比及丙烯酸单体用量。     

口腔溃复平膜剂的研究

目的：优选口腔溃复平膜剂（黄柏，龙胆草，青黛等）最佳处方。建立膜剂中盐酸小檗碱含量的测定方法。方法：以膜剂外观和融化时间为指标。采用L9（3^4)正交试验筛选处方，反相液相色谱法测定膜剂中盐酸小檗碱的含量。结果：膜剂最佳处方为：中药提取液40mL,PVA0.588:PVA1788为4：1.5，甘油含量8%，CMC-Na0.25g；测定方法中盐酸小檗碱的平均回收率为97.7%。结论：膜剂的外观（包括可塑性，粘附性及抗拉强度）和融化时间等指标均符合质量标准的要求，采用反相液相色谱法可有效控制溃复平膜剂中盐酸小檗碱的含量。     

An Investigation into the Changes in Airway Dimension and the Efficacy of Mandibular Advancement Appliances in Subjects with Obstructive Sleep Apnoea

Abstract

This prospective clinical study evaluates a group of 37 male Caucasians with obstructive sleep apnoea for changes in airway dimension and the efficacy associated with the use of mandibular advancement splints. Lateral skull radiographs were obtained with the subjects—upright in occlusion, supine in occlusion, and supine in protrusion. Each radiograph was traced and digitized, and changes in mandibular position, airway dimensions, and hyoid were examined. Subjects were invited to complete pre- and post-treatment questionnaires, and interviewed following fitting of a removable Herbst mandibular advancement splint.

Significant changes were recorded in the airway dimensions in response to both a change in position, from upright to supine, and in response to mandibular advancement. A compliance rate of 76 per cent was achieved with no reported serious complications associated with the use of mandibular advancement devices.     

Teaching diagnostic approach to a patient through cinema

Films are produced with the aim of entertaining people, but recently there has been increasing use of films to educate medical trainees about various disorders, symptoms of these disorders, patient–therapist interactions, and various other medical and psychiatric issues. Discussions in academic circles have moved from criticism of negative portrayals of mental illness in earlier films to their use in teaching sessions. Films can be used either in full length or clip format to conduct training modules. Use of the film Stigmata to train residents about diagnostic dilemmas and taking a diagnostic approach to patients is discussed.     

Detecting anomalies in a deliberately biased tomotherapy plan: Comparison of two patient-specific quality assurance processes involving ArcCHECK® and Gafchromic® EBT3 films

Purpose

This work proposes a comparative evaluation of two of our patient-specific quality assurance processes involving ArcCHECK^® (Sun Nuclear) and Gafchromic^® EBT3 films (Ashland) in order to determine which detector is able to most effectively detect an anomaly in a deliberately biased tomotherapy plan.

Emotional responses in borderline personality disorder and depression: assessment during an acute crisis and 8 months later

Stability of subjective emotional responses to positive and negative film stimuli was examined in female patients with borderline personality disorder (BPD, n = 30), depressed patients (n = 27) and a non-clinical control group (n = 30). At first assessment (t1) clinical participants were inpatients. The second assessment was conducted 8 months later, when clinical participants were not in an acute crisis. Positive emotions and other-focused negative emotions were successfully induced in all participants. Altogether, more negative baseline emotionality describes both patient groups better than differences in emotional reactivity. Our findings contradict the hypothesis of general emotional hyperreactivity in BPD patients for both positive and negative emotions.     

医用Ta5+掺杂TiO2生物薄膜材料的合成与性能研究

利用射频控溅射技术合成Ta^5 掺杂的TiO2薄膜材料。采用X射线衍射（XRD）和电子能谱（XPS）等技术对薄膜的成分和结构进行了分析,并利用动态凝血时间测定法和血小板粘附试验研究了薄膜的血液相容性,同时对薄膜的硬度、耐磨性等力学特性进行了研究和评价。结果表明,Ta^5 掺杂的TiO2薄膜不仅具有良好的血液相容性,同时还具有较优的力学耐久性能。     

X线平片与多层螺旋CT诊断肋骨骨折结果的对比分析

目的比较X线平片与多层螺旋CT对肋骨骨折诊断结果的准确率。方法对160例肋骨骨折患者X线平片与多层螺旋CT结果，并进行对比分析。结果160例患者，总计251处肋骨骨折，多层螺旋CT诊断符合率100％：X线平片检查共发现明确肋骨骨折169处，检出率为67．3％，漏诊率为33．7％。结论多层螺旋CT能有效地避免X线平片和常规CT的不足，降低了漏诊率，为患者治疗方案的选择，提供了可靠的诊断依据。     

Preparation, Characterization, and Antitumor Efficacy of Biodegradable Poly(lactic acid) Methotrexate Implantable Films

Implantable methotrexate films using poly(D,L-lactic acid) and poly(L-lactic acid) (PLA) of different molecular weights were prepared. The in vitro drug release was dependent on the drug loading and molecular weight of the PLA. By blending these polymers in different ratios, the drug release could be controlled and modified. The antitumor efficacy in Sarcoma-180 tumor-bearing mice revealed that the implantable film was more efficacious than subcutaneous injection of plain methotrexate.