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目的 更好的了解糖尿病酮症酸中毒DKA的诊治.方法 回顾性分析我科已治愈的31例DKA患者的临床资料,在补液、祛除诱因及纠正电解质紊乱、酸碱平衡等治疗的基础上均给予小剂量胰岛素静脉滴注.结果 30例临床治愈出院,1例死亡.结论 DKA患者综合治疗合理应用小剂量胰岛索可提高疗效. 相似文献
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目的观察胰岛素泵联合胰岛素滴注治疗酮症酸中毒﹙DKA﹚的疗效。方法将2008年4月～2011年6月收治的DKA患者36例分为治疗组18和对照组18例,治疗组给予胰岛素泵全程治疗,结合小剂量胰岛素持续点滴,对照组给予小剂量胰岛素治疗。比较两组患者血糖变化、DKA纠正时间及住院时间。结果治疗组血糖下降相对稳定,酸中毒纠正时间短于对照组,且无反复;治疗过程中治疗组未出现低血糖,对照组出现3例;住院时间治疗组短于对照组。结论胰岛素泵联合胰岛素滴注治疗酮症酸中毒安全有效。 相似文献
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Matthew G Clark Abdallah Dalabih 《Journal of clinical research in pediatric endocrinology》2014,6(3):190-191
Management protocols have been shown to be effective in the pediatric emergency medicine (PEM) and pediatric critical care (PCC) settings. Treatment protocols define clear goals which are achieved with consistency in implementation. Over the last decade, many new recommendations have been proposed on managing diabetic ketoacidosis (DKA). Although no perfect set of guidelines exist, many institutions are developing DKA treatment protocols. We sought to determine the variability between institutions in implementation of these protocols. 相似文献
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B.K. Mishra P. Shukla M. Aslam A.A. Siddiqui S.V. Madhu 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):839-842
Background
It is being increasingly reported that some of the youth onset diabetes patients cannot be classified clearly as type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM) based on usual criteria and the term double diabetes (DD) coined for these cases.Aim
The objective of the study was to find out the prevalence of DD in youth onset diabetes patients from east Delhi and neighboring NCR region.Methods
A total of 200 patients with youth onset diabetes below 25 years of age were recruited from a tertiary care hospital in East Delhi. Clinical history, family history of diabetes and anthropometry of patients were recorded. Fasting serum C-peptide, Anti-IA2-antibody and Anti-GAD-antibody were measured in all patients. Patients positive for Anti-GAD-antibody (>1.05 U/ml) and C-peptide level >0.3 nmol/l were characterized as DD patients. Patients negative for Anti-GAD-antibody and C-peptide >0.3 nmol/l were kept under the category of T2DM. Patients with low C-peptide level along with one of the following, positive Anti-GAD-antibody, positive Anti-IA2-antibody and diabetic ketoacidosis (DKA) were considered as T1DM. Remaining patients were kept under the unknown category.Results
Mean age of study subjects was 18.2 ± 7.1 years. Seven percent (7%) of the subjects were classified as DD, 51% as T1DM, 13% as T2DM and 29% were kept under the unknown category. Mean age of subjects with 22.2 ± 9.7, 16.9 ± 6.7, 20.6 ± 7.7 and 19.4 ± 7.4 years in DD, T1DM, T2DM and unknown category respectively. Mean BMI of subjects with DD, T1DM, T2DM and unknown category was 19.8 ± 5.7, 16.6 ± 3.7, 19.3 ± 4.1 and 18.0 ± 4.6 kg/m2 respectively.Conclusion
Double diabetes is an important occurrence among youth onset diabetes subjects. Only half of the subjects with youth onset of diabetes had T1DM. 相似文献6.
Moshe Phillip MD Chantal Mathieu MD Marcus Lind PhD Eiichi Araki MD Paolo di Bartolo MD Richard Bergenstal MD Simon Heller MD Lars Hansen MD Markus Florian Scheerer PhD Fredrik Thoren PhD Niki Arya MSc John Xu PhD Nayyar Iqbal MD Paresh Dandona MD DEPICT- DEPICT- Investigators 《Diabetes, obesity & metabolism》2021,23(2):549-560
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文秀保 《中国现代药物应用》2011,5(3):53-54
目的研究糖尿病酮症酸中毒（DKA）诱发因素及诊治情况,以期提高DKA正确诊断率和成功抢救率。方法对确诊的DKA患者进行胰岛素、迅速扩容,维持有效循环等有效治疗,观察其纠正DKA的疗效,并统计每个患者的诱发因素。结果除2例因休克、多脏器功能衰竭死亡外,其余38例患者血糖、血钾、血氯等恢复正常,尿酮、血酮消失,DKA纠正出院。结论 DKA在正确诊断的基础上,尽快给予胰岛素、扩容,维持有效循环是治疗成功的关键。 相似文献
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