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排序方式: 共有208条查询结果,搜索用时 15 毫秒
1.
《Foot and Ankle Surgery》2020,26(2):193-197
BackgroundThe aim of this study was to compare the radiographic and functional results between fixation and non-fixation in the Cotton osteotomy for the treatment of adult acquired flatfoot.MethodsA retrospective, case-controlled study of consecutive stage IIB posterior tibial tendon dysfunction (PTTD) patients treated with the same bony reconstructive surgery including cotton osteotomy between 2013 and 2017. Meary’s angle, the medial arch sag angle (MASA), and medial cuneiform cobb angle (MCCA) were evaluated pre-operation, at first weight bearing after surgery, and 12 months post operation.ResultsForty feet were included in the study. The cotton osteotomy utilized screw fixation (n = 20) or non-fixation technique (n = 20). No significant differences between groups were found in pre-operative and follow-up radiographic parameters, union rate, and functional results.ConclusionThe non-fixation with press fit technique is a reliable procedure for Cotton osteotomy and as effective as screw fixation.Level of evidenceLevel III, case control study 相似文献
2.
目的 评价棉尘对工人肺功能的影响。方法 对 14 6名接棉尘工人和 12 5名对照工人的肺活量(FVC)和第 1秒时间肺活量 (FEV1 0 )进行了检查。结果 前纺、后纺和细纱作业场所空气中的棉尘浓度几何均值分别为 (7 1± 8 7) ,(2 5± 1 7) ,(2 2± 2 4 )mg/m3 ,样品超标率 16 8%。接触组前纺、后纺工人的急性肺功能改变 (APFC)和前纺工人的慢性肺功能改变 (CPFC)检出率较对照组明显增高 (P <0 0 5 ) ,OR及 95 %CI分别为 4 7(1 4~ 16 3) ,4 5 (1 3~ 15 6 ) ,5 6 (1 1~ 2 9 8) ;4 0~岁年龄段接棉尘工人APFC检出率高于对照工人 (P <0 0 5 ) ,OR及 95 %CI为 9 0 (1 1~ 73 8) ;接棉尘女工APFC检出率也比对照女工高 (P <0 0 1)。结论 棉尘有损害肺通气功能的作用 ,以急性改变更为明显 相似文献
3.
双氯酚酸钠米索前列醇片的抗炎作用研究 总被引:3,自引:0,他引:3
双氯酚酸钠米索前列醇片(DSMT)(20,10mg/kg)连续2d灌胃给药可显著地抑制二甲苯所致鼠耳肿胀(P〈0.01,P〈0.05);DSMT(15,7.5mg/kg)灌胃给药均可非常显著抑制角叉菜胶至炎后3h内大鼠足肿胀;DSMT高、低剂量组(15,7.5mg/kg)灌胃给药7ddisplay structure 相似文献
4.
5.
Fragrance finishing of textile has been enormously increased and used in domestic and industrial application. Fragrance can be synthesis chemically but available in natural and inorganic. The investigation of this research is to study the combined effect of fragrance and antimicrobial finishing on cotton fabric by lavender essential oil with the use of β-Cyclodextrin, Chitosan citrate and β-Cyclodextrin/Grafted Chitosan through pad-dry method. Fourier Transform Infrared spectroscopy (FTIR) was used to study the formation of ester bonds between β-cyclodextrin/grafted chitosan and cotton celluloses. For all the finished fabric samples fragrance release rate performance and antimicrobial properties were measure by standard test methods. The results revealed that β-CD was highly soluble in 0.6 gpl NaOH solution and 80 gpl β-CD and 6% essential lavender oil solutions were found to be a most suitable combination for fragrance and antimicrobial finishing. FTIR studies reveal about the formation of a carboxylic ester between cotton and β-Cyclodextrin/Grafted Chitosan at 1730 cm?1 ester peak. 相似文献
6.
Bożena Czech Kamyar Shirvanimoghaddam Edyta Trojanowska Minoo naebe 《Sustainable Chemistry and Pharmacy》2020
The significant rise in contamination of wastewater, water and ground water or sediments with PPCPs is a clear evidence that nowadays applied treatment methods are inefficient in removal of these contaminants. In this study a novel cotton based adsorbent is used for efficient sorption of naproxen (NAP), caffeine (CAF) and triclosan (TCS). The adsorption of tested contaminants differed significantly: the highest amount of PPCPs sorbed was noted for TCS sorption onto CMT9 137 mg g?1, whereas the lowest adsorbed amount, 19.73 mg g?1, was observed for NAP sorption onto CMT13. The presence of co-solute affected both the mechanism of sorption and the amount of PPCPs sorbed: in the presence of TCS the sorption of NAP was changed from chemical to physical. Similarly, in the presence of TCS the mechanism of NAP sorption onto CMT13 changed from chemisorption to diffusion inside the pores. The presence of CAF definitely increased NAP sorption and partitioning. The presence of TCS increased CAF sorption, whereas the presence of NAP in the solution increased CAF sorption only onto CMT11. The NAP sorption in the presence of CAF was significantly enhanced and data confirmed that diffusion through the pores is the most often observed mechanism of selected PPCPs sorption onto CMTs. It is believed that the synthesized cotton-based adsorbents offer a unique opportunity for the sustainable PPCP removal from wastewater. 相似文献
7.
《Vaccine》2018,36(52):8069-8078
Human respiratory syncytial virus (RSV) is the leading cause of severe lower respiratory tract infections in newborns, young children, elderly, and immune-compromised. The RSV fusion (F) glycoprotein is a major focus of vaccine development and the target of palivizumab (Synagis®) which is licensed as an immuno-prophylactic for use in newborn children at high risk of infection. However, clinical use of a narrowly targeted monoclonal antibodies leads to the generation of escape mutant strains that are fully resistant to neutralization by the antibody. Herein, we evaluated the RSV F nanoparticle vaccine (RSV F vaccine), produced as near-full-length, pre-fusogenic F trimers that form stable protein-detergent nanoparticles. The RSV F vaccine induces polyclonal antibodies that bind to antigenic site II as well as other epitopes known to be broadly neutralizing. Cotton rats immunized with the RSV F vaccine produced antibodies that were both neutralizing and protected against wild-type RSV infection, as well as against a palivizumab-resistant mutant virus. Use of aluminum phosphate adjuvant with the RSV F vaccine increased site II antibody avidity 100 to 1000-fold, which correlated with enhanced protection against challenge. The breadth of the vaccine-induced antibody response was demonstrated using competitive binding with monoclonal antibodies targeting antigenic sites Ø, II, IV, and VIII found on pre-fusion and post-fusion conformations of RSV F. In summary, we found the RSV F vaccine induced antibodies that bind to conserved epitopes including those defined as pre-fusion F specific; that use of adjuvant increased antibody avidity that correlated with enhanced protection in the cotton rat challenge model; and the polyclonal, high-avidity antibodies neutralized and protected against both wild-type and palivizumab-resistant mutant virus. These data support the ongoing clinical development of the aluminum phosphate adjuvanted RSV F nanoparticle vaccine. 相似文献
8.
Ruben Marroquin-Segura Maurilio Flores-Pimentel Rodolfo Carreón-Sánchez Martha M. Garcia-Burciaga José Luis Alfredo Mora-Guevara Abigail Aguilar-Contreras Vicente Jesús Hernandez-Abad 《Journal of ethnopharmacology》2009
Aims of study
Despite the ethnopharmacological relevance of Helietta parvifolia A. Gray (Rutaceae) in Mexico, we found no significant pharmacological studies of this plant in the scientific literature. The aim of the present study was to establish the anti-inflammatory effect of an aqueous extract of the stem bark of Helietta parvifolia in mice.Materials and methods
The anti-inflammatory activity of the aqueous extract of the stem bark of Helietta parvifolia was evaluated using carrageenan-induced paw oedema in mice, and the cotton pellet granuloma method.Results
An extract dose ranging from 20 to 80 mg/kg p.o. showed a non-significant effect over the initial phase of carrageenan-induced oedema. However, it showed a significant inhibition of oedema after 3 h, which can be related to the inhibition of the release of kinin-like substances. An ID50 value of 47.4 mg/kg was obtained for the plant extract. The extract also suppressed granulomatous tissue formation during chronic inflammation. The inhibitory values were 19.2, and 22.2, corresponding to 40 and 80 mg/kg doses of extract respectively.Conclusions
Aqueous extract showed a statistically significant anti-inflammatory effect in mice during the late phase of acute inflammation and during chronic inflammation. However, the exact mechanism(s) of anti-inflammatory effects of Helietta parvifolia observed in this study remains unclear. 相似文献9.
Aim of the study
Albizia lebbeck Benth. is used both in Indian traditional system and folk medicine to treat several inflammatory pathologies such as asthma, arthritis and burns. The aim of the present study was to evaluate the scientific basis of anti-inflammatory activity of different organic solvent extracts of Albizia lebbeck.Materials and methods
The anti-inflammatory activity of Albizia lebbeck was studied using the carrageenan, dextran, cotton pellet and Freund's complete adjuvant induced rat models. The extracts obtained using petroleum ether, chloroform and ethanol were administered at the concentrations of 100, 200 and 400 mg/kg body weight.Results
The petroleum ether and ethanol extracts at 400 mg/kg, showed maximum inhibition of inflammation induced by carrageenan (petroleum ether—48.6%; ethanol—59.57%), dextran (petroleum ether—45.99%; ethanol—52.93%), cotton pellet (petroleum ether—34.46%; ethanol—53.57%) and Freund's adjuvant (petroleum ether—64.97%; ethanol—68.57%).Conclusion
The marked inhibitory effect on paw edema shows that Albizia lebbeck possesses remarkable anti-inflammatory activity, supporting the folkloric usage of the plant to treat various inflammatory diseases. 相似文献10.