益气通阳化痰方联合迈之灵治疗下肢深静脉血栓形成的临床研究

目的:研究益气通阳化痰方联合迈之灵治疗下肢深静脉血栓形成的临床疗效。方法:将60例下肢深静脉血栓形成患者随机分为单药治疗组和联合治疗组,两组均予迈之灵口服治疗,联合治疗组加用益气通阳化痰方,10天为1个疗程,两个疗程后分析临床疗效,肢体阻抗血流图和血液流变学变化。结果:联合治疗组在疼痛缓解、下肢肿胀消退、血粘度及肢体血流的改善方面明显优于迈之灵单药治疗组;两组总有效率比较差异具有显著性。结论:益气通阳化痰方联合迈之灵治疗下肢深静脉血栓形成具有较好疗效。     

强力稀化粘素治疗稳定期支气管扩张症的疗效观察

目的 观察强力稀化粘素对稳定期支气管扩张症的疗效.方法 对35例稳定期支气管扩张患者,强力稀化粘素300 mg每日3次口服治疗,疗程6个月.观察并记录支扩急性加重的频率、临床表现并与治疗前6个月进行比较.结果 35例患者完成了6个月的治疗和随访.6个月来患者的平均恶化次数从治疗前4.2次减少到1.3次；痰量从治疗前的平均0.066 L/d减少至0.034 L/d.结论 长期强力稀化粘素治疗能减少支扩恶化次数,改善临床症状.     

迈之灵对下肢慢性静脉功能不全患者微循环的改善效果

目的分析迈之灵对下肢慢性静脉功能不全(CVI)患者微循环指标的改善情况。方法入选2016年3月至2017年8月中国医学科学院北京协和医院和赤峰市医院血管外科门诊就诊的CVI患者40例,根据治疗方式分为迈之灵组23例和对照组17例。迈之灵组给予迈之灵及弹力袜治疗,对照组仅采用弹力袜治疗,疗程为4周。观察主要疗效指标[流行病学和经济研究(VEINES)/生活质量(QOL)/症状(Sym)问卷评分、经皮氧分压(TcPO_2)、皮肤温度]、次要疗效指标(温控血流及阻断后反应性充血)和不良反应,并对疗效和安全性进行评估。采用SPSS 20.0统计软件进行数据处理及分析。组间比较采用t检验、Mann-Whitney U检验或χ~2检验。结果完成病例36例,迈之灵组22例,对照组14例。迈之灵组治疗前相比治疗后VEINES-QOL[(69.3±13.5)vs(76.7±11.9)分]、VEINES-Sym[(31.9±7.9)vs(36.0±7.4)分]、TcPO_2[(45.2±22.3)vs(56.3±16.5)mm Hg]、皮肤温度[32.6(31.5,33.9)℃vs 31.8(31.0,32.9)℃]和温控血流[(151.4±123.0)%vs(418.0±179.5)%]差异均有统计学意义(P0.05)。对照组治疗前相比治疗后VEINES-QOL[(64.0±16.1)vs(69.0±16.7)分]、VEINES-Sym[(29.3±7.7)vs(32.6±7.9)分]和TcPO_2[(39.6±16.8)vs(51.4±9.9)mm Hg]差异有统计学意义(P0.05)。迈之灵组相比对照组治疗前后的温控血流差值[(266.6±170.1)%vs(-110.1±160.5)%]差异有统计学意义(P0.05)。结论迈之灵在一定程度上可改善CVI患者生活质量及临床症状,其疗效可能与其对下肢微循环的改善作用有关。微循环指标中TcPO_2、皮肤温度、温控血流可能在一定程度上反映CVI患者下肢微循环的变化。CVI的发病机制可能与下肢微循环改变有密切关联。     

Transnasal Fixation of NOE Fracture: Minimally Invasive Approach

Purpose  

Nasal fractures may occur in association with other facial injuries like Le-forte II and III and also severe comminuted midface fractures or by themselves. Bony fractures of the nose may involve one or both nasal bones, the frontal process of the maxilla, the bony septum, and in severe trauma the nasal–orbital–ethmoid complex. Treatment of these fractures range from closed reduction and support to open reduction and miniplate osteosynthesis. Purpose of this article is to describe a technique of managing nasal bone fractures associated with midface fractures.     

日本产电热蚊香片滴加液单剂及混剂对成蚊药效的评价

用日本住友化学株式会社生产的电热蚊香滴加液，配制了７个配方的电热片，对成蚊进行药效测定。结果表明：①益多克对成蚊的药效是强力毕那命的４．８倍以上；②强力毕那命３２ｍｇ、益多克４ｍｇ配制的驱蚊片，对成蚊击倒速度最佳，其它依次为：强力毕那命２８ｍｇ、益多克５ｍｇ及强力毕那命２４ｍｇ、益多克６ｍｇ：但致死效果以后者为佳；③野外品系成蚊对两种药剂均较敏感。     

七叶皂苷片促进合并组织学炎症的前列腺增生患者术后下尿路症状的改善

目的探讨将七叶皂苷片应用于合并前列腺组织学炎症的前列腺增生（BPH）患者,观察其对经尿道前列腺电切术（TURP）后早期下尿路症状（LUTS）的改善作用。 方法2015年11月至2018年5月,我院116例合并前列腺组织学炎症的BPH患者,随机分为治疗组（n=58）和对照组（n=58）,均行TURP。治疗组在对照组基础上,从手术后第3天起开始口服七叶皂苷片2片/次,2次/d,直至拔导尿管后4周。记录两组患者术前、拔管后第7天和拔管后第28天的国际前列腺症状评分（IPSS）和生活质量（QOL）评分,并记录两组急性尿潴留（AUR）和急迫性尿失禁（UUI）发生的例数。 结果两组患者术后IPSS和QOL评分均较术前有明显下降,但治疗组较对照组的IPSS和QOL评分下降幅度更大,差异有统计学意义（P<0.05）,治疗组发生UUI的例数明显少于对照组,差异有统计学意义（P<0.05）,而两组发生AUR的例数差异无统计学意义。 结论七叶皂苷片可以促进合并前列腺组织学炎症的BPH患者TURP术后早期LUTS的改善。     

标准桃金娘油的临床应用进展

目的 介绍祛痰药标准桃金娘油的临床研究与应用进展.方法 查阅国内外文献,进行分析和归纳.结果 标准桃金娘油临床应用广泛,对呼吸系统疾病、耳疾病、喉疾病等均有良好的疗效.结论 标准桃金娘油具有重要的临床应用价值,随着研究的深入,其临床应用将有更大的发展空间与潜力.     

Efficacy of Aescuven forte on male infertility with varicocele

Objective:To explore the effectiveness of Aescuven forte in treatment of male infertility with varicocde.Methods:One hundred and forty-three male patients with infertility with vsricocele were randomly divided into medication group,control group and surgery group.Among them,seventy-four patients in medication group took Aescuven forte(0.3g,2/day)for 2-3 months combined with other medicine availing for semen quality.Semen was analyzed and the diameter of vena spermatica interns was measured with ultrasound before and after the treatment.Forty-one patients in control group only took the same medicine availing for semen quality.Twenty-eight patients in surgery group accepted varicocelectomy and took the same medicine availing for semen quality after the operation.Results:After the operation or medication,the improving rates for the sperm density in medication group,con-trol group and surgery group were 53.2%,39.0%,and 67.9% respectively.The significant difference existed be-tween control group and surgery group(P<0.05).The improving rates for the sperm motility in the three groups were 51.6%,46.3%,and 71.4% respectively.The significant difference existed between control group and surgery group(P<0.05).After Aescuven forte treatment,the effective retracting rates for the 108 sides varicocele in 74 patients in medication group reached 43.5%.The effective retracting rates for varicoeele in mild,moderate and se-vere varicocele group defined by the diameter of the vessel were 39.2%,60.7%,and 16.7% respectively.The im-proving rate in moderate varicocele group was much higher than that in the other two group.(P<0.05)Conclusion:Aescuven forte combined with other medicine can improve semen quality in male infertility with vari-cocele.It can retract the vein to some degree in some patients with varicocele,especially for the patients with middle degree varicocele.It could be a therapeutic choice for male infertility with varicocele.