放射状角膜切开的实验病理与临床应用

以１４只兔及２只猴为动物模型，对放射状角膜切开术（ＲＫ）进行了２￣３个月观察，发现：ＲＫ切口内的上皮塞子持续２个月以上才逐渐消退。术后一个月内上皮下基底膜形成，后逐渐变薄，切口内的成纤维细胞分裂增殖较慢，开始走行与切口平行，１５天后可见横过切口，２月后实质表层成纤维细胞排列变得整齐，但深层仍较紊乱，胞核多深染。术中切穿角膜的实验兔，术后２个月病理切片可见：切口附近内皮细胞丢失，内弹力膜断裂，切口内     

儿童散光度散光轴向的分析

目的:探讨3～10岁儿童散光度散光轴向分布情况。方法:10g/L阿托品常规散瞳验光检查2299眼。结果:3～10岁儿童散光度分布在0.25～2.00D,合例散光占96.35%,反例散光占0.52%,斜轴散光占3.13%。结论:3～10岁儿童散光以合例散光为主,斜轴散光次之,极少部分为反例散光。     

Corneoplastique?: Art of vision surgery

Corneoplastique incorporates the entire spectrum of Vision corrective surgery including Lasik, premium cataract surgery, corneal surgery, ocular surface surgery and the full range of anterior segment surgery itself in manipulating the optics of every eye towards unaided emmetropia to define each and every eye surgeon as a “Vision Corrective Surgeon”. This concept of approaching each case individually and designing vision therewith enables surgeons to correct not only virgin eyes but also approach complex cases and complications with the goal of 20/20 vision. Armed with this holistic approach, eye surgeons can use minimally invasive, aesthetically pleasing and visually focused surgery in single or staged process aiming for each patient''s Best Vision Potential (BVP) raising eye surgery itself then to an Art!     

放射状角膜切开术在轻中度圆锥角膜病例中视觉康复的疗效

目的：探讨放射状角膜切开术在轻中度圆锥角膜治疗中光学和视力康复的效果。
　　方法：回顾性分析应用放射状角膜切开术治疗圆锥角膜的病例22例31眼并进行了至少12 mo的随访。测量并分析术前术后裸眼视力,最佳矫正视力,自动屈光计值,角膜曲率,角膜不规则指数以及并发症。
　　结果：在最后一次随访中,平均裸眼视力( logMAR)由0.86±0.34显著提升至0.30±0.29(P<0.0001),平均最佳矫正视力由0.47±0.21提升至0.17±0.23(P<0.0001)。平均角膜曲率由48.69±3.68 D 降低至44.33±3.09 D ( P<0.0001)。自动屈光计测得平均等效球镜值由-5.61±2.85D显著提升至-2.29±1.95D(P<0.0001)。在整个随访过程中,中央角膜厚度和3mm,5mm区域的角膜不规则指数均无变化。术中和术后没有观察到严重并发症。
　　结论：在本组病例中,放射状角膜切开术是轻中度圆锥角膜视觉康复的有效治疗方法。     

A prospective study investigating the long-term stability of changes in astigmatism following arcuate lamellar keratotomy (ALK): 3-year results

Introduction: The correction of low to moderate astigmatism is possible today by means of photoablation (PRK), while the treatment of moderate and higher astigmatism still involves refractive keratotomy. Experience has shown that cataract surgery, using modern tunnel techniques with self-healing incisions, results in earlier stability in both the refractive outcome and wound healing. In this study, we attempted to combine the advantages of lamellar keratotomy with those of a pair-wise T-incision as arcuate lamellar keratotomy (ALK). Patients and methods: The clinical outcome of 41 patients who underwent ALK was investigate in a prospective study over a period of 3 years. The pre- and postoperative investigations undertaken included the measurement of astigmatism using a Zeiss keratometer, uncorrected visual acuity, and corrected glare vision using a Humphrey autorefractor. All patients had astigmatism between 2.0 and 7.0 D. Together with a uniform arcuate incision, we used 7 mm (n = 26) and 8 mm (n = 15) mm zones for correction. Results: The average preoperative astigmatism was 4.01 ± 1.90 (median, 3.50) D. After a 3-year follow-up the average postoperative astigmatism was 1.59 ± 1.29 (median, 1.38) D. The astigmatic change induced (Jaffé) after 3 years was about 3.23 ± 2.23 (median, 3.16) D. The average uncorrected visual acuity (log MAR) before ALK was 0.20 ± 0.12 (median, 0.22) and after follow-up, 0.41 ± 0.14 (median, 0.39). Corrected glare vision before surgery was 0.23 ± 0.19 (median, 0.10) and afterwards, 0.25 ± 0.22 (median, 0.14). Conclusions: Arcuate lamellar keratomy (ALK) stood the test as a routine clinical procedure for correction of moderate astigmatism with stable postoperative functional outcomes. We did not find impairment of glare vision following this procedure.      

放射状角膜切开术矫正准分子激光角膜切削术后残余近视

目的 评价放射状角膜切开术（ＲＫ）矫正准分子激光角膜切削术（ＰＲＫ）后残余近视的安全性、有效性及有关并发症。方法 分析１０例病人１４只眼用ＲＫ手术矫正ＰＲＫ后残余近视的屈光及视力变化。ＲＫ后最短观察时间６个月。结果 ３只眼（２１％）接受１次ＰＲＫ治疗，７只眼（５０％）接受２次ＰＲＫ治疗，４只眼（２９％）接受３次ＰＲＫ治疗。１１只眼（７９％）接受４刀Ｒ人眼（２１％）接受８刀ＲＫ术。所有病人ＲＫ术后裸     

角膜放射状切开术相关因素及预测性

对连续性１０５例（２０８眼）角膜放射状切开术患者进行了术后半年至一年的前瞻性研究。应用多元回归法分析手术相关因素，发现手术效果与切口深度，条数，原近视度数及术后加压等因素相关，其中前二项为主要因素。以二种方法计算了手术预测性；９０％可信限表示为３．１０ＤＳ；预期值与实际值之差在１．０，１．５，２．０以及３．０ＤＳ以内者分别为６２％，７６％，８４％和１００％。设计了自己的手术公式并制成计算机软件。     

Corneal scarring and irregular astigmatism following refractive surgery in a corneal transplant

Background: Scarring may follow refractive surgery, causing irregular astigmatism and loss of visual acuity. Methods: A case report of scarring and irregular astigmatism occurring in a corneal transplant following photorefractive keratectomy and arcuate incisions is presented. Results: Following surgical excision of the scan unaided visual acuity improved from 1/60 to 6/12. Histopathology of the excised scar was obtained. Conclusions: Refractive surgery following corneal transplantation may produce scarring. The origin of the scar in the present case has not been established.