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1.
Thirty randomly oriented T’s were presented in a circle around fixation at an eccentricity of 11° such that each T was crowded by its neighbors. Two locations within the same hemifield (unilateral condition) or one location in each hemifield (bilateral condition) were precued for subsequent probing. Observers were then asked to report the orientation of a target T at one of these locations. A bilateral field advantage was found: target identification was better when the two precued targets were in different hemifields than when they were within the same hemifield. This bilateral advantage was absent when only targets were presented, without any distracters. Further controls showed that this advantage could not be attributed to differences between horizontal and vertical target alignments or to visual field anisotropies. A similar bilateral advantage has been reported for multiple object tracking (Alvarez, G. A., & Cavanagh, P. (2005). Independent resources for attentional tracking in the left and right visual fields. Psychological Science 16(8), 637-643) and other attentional tasks. Our results suggest that crowding also demonstrates separate attentional resources in the left and right hemifields. There was a cost to attending to two targets presented unilaterally over attending to a single target. However, this cost was reduced when the two crowded targets were in separate hemifields. 相似文献
2.
Crowding can substantially affect the transition of a protein between its native (N) and unfolded (U) states via volume exclusion
effects. Also, it influences considerably the aggregation (A) of unfolded proteins. To examine the details, we developed an
approach for computing the kinetic rates of the process N ↔ U → A in which the concentration of the protein is explicitly
taken into account. We then compute the relative change with temperature of the protein denaturation for various fractional
volume occupancies and partition of proteins in solution. The analysis indicates that, in protein solutions in which the average
distance between proteins is comparable with the radius of gyration of an unfolded protein, steric effects increase the stability
of the proteins which are in compact, native states. In heterogeneous protein solutions containing various types of proteins
with different thermal stabilities, the unfolding of the most thermolabile proteins will increase the stability of the other
proteins. The results shed light on the way proteins change the thermal stability of a cell as they unfold and aggregate.
This study may be valuable in questions related to the dynamics of thermal injuries. 相似文献
3.
4.
Ryan M. Gardner Nathan A. Friedman Michael Carlson Tamala S. Bradham Tyler W. Barrett 《The American journal of emergency medicine》2018,36(1):124-127
Background
Emergency department (ED) crowding is associated with patient safety concerns, increased patients left without being seen (LWBS), low patient satisfaction, and lost ED revenue. The objective was to measure the impact of a revised triage process on ED throughput.Methods
This study took place at an urban, university-affiliated, adult ED with an annual census of 70,000 and admission rate of 34%. The revised triage approach included: identifying eligible patients at triage based on complaint, comorbidities, and illness acuity; and reallocating a nurse practitioner (NP) into our triage area. We trialed the intervention from 1100–2300 on weekdays from January 13–26, 2016. Adult patients who were not likely to require intensive evaluations were eligible. Primary outcomes were throughput measures including: time to provider, ED length of stay (LOS), and LWBS. Pre- and post-intervention metrics were compared using the Mann-Whitney U test, given the non-normal distribution of the metrics.Results
The NP evaluated 120 patients of which 101 (84%) were discharged, 3 (2.5%) admitted, and 16 (13%) required more intense evaluation. Time to provider decreased from a median (IQR) of 42 (16, 114) to 27 (12.4, 81.5) minutes (p < 0.01) and ED LOS from 290 (194.8, 405.6) to 257 (171.2, 363.4) minutes (p < 0.01) for all patients not admitted and not requiring a consult. LWBS decreased from a pre-trial 4.6% to 2.2% (p < 0.01).Conclusion
The revised triage intervention was associated with improvements in several ED throughput metrics and a reduction in LWBS. 相似文献5.
目的探讨使用铸造式扩弓器非拔牙矫治安氏Ⅰ类错(?)伴轻中度牙列拥挤病例的临床疗效,为临床应用提供依据。方法选取32例安氏Ⅰ类错(?)畸形伴轻中度牙列拥挤病例。其中17例采用铸造式上颌扩弓配合固定矫治技术进行非拔牙正畸治疗(实验组);15例仅采取非拔牙的固定矫治(对照组)。分别在T1(正畸治疗前)、T2(正畸治疗结束)拍摄头颅侧位定位片并测量分析。结果头影测量分析显示两组间下颌平面角及前面高的增加无统计学差异(P>0.05)。对照组上前牙明显较扩弓组唇倾(P<0.05),下前牙唇倾量均有增加(扩弓组=4.05°,对照组=7.16°,P>0.05)。扩弓组上、下前牙突距(U1-NA和L1-NB)变化量更小(P<0.05)。两组间上颌磨牙垂直高度的变化无显著性差异。结论铸造式扩弓器在扩宽牙弓解除拥挤的同时,能有效地控制磨牙高度及面下1/3高度的变化。 相似文献
6.
《Journal of emergency nursing》2023,49(1):86-98
IntroductionPatients leaving the emergency department before treatment (left without being seen) result in increased risks to patients and loss of revenue to the hospital system. Rapid assessment zones, where patients can be quickly evaluated and treated, have the potential to improve ED throughput and decrease the rates of patients leaving without being seen. We sought to evaluate the impact of a rapid assessment zone on the rate of patients leaving without being seen.MethodsA pre- and post-quality improvement process was performed to examine the impact of implementing a rapid assessment zone process at an urban community hospital emergency department. Through a structured, multidisciplinary approach using the Plan, Do, Check, Act Deming Cycle of process improvement, the triage area was redesigned to include 8 rapid assessment rooms and shifted additional ED staff, including nurses and providers, into this space. Rates of patients who left without being seen, median arrival to provider times, and discharge length of stay between the pre- and postintervention periods were compared using parametric and nonparametric tests when appropriate.ResultsImplementation of the rapid assessment zone occurred February 1, 2021, with 42,115 ED visits eligible for analysis; 20,731 visits before implementation and 21,384 visits after implementation. All metrics improved from the 6 months before intervention to the 6 month after intervention: rate of patients who left without being seen (5.64% vs 2.55%; c2 = 258.13; P < .01), median arrival to provider time in minutes (28 vs 11; P < .01), and median discharge length of stay in minutes (205 vs 163; P < .01).DiscussionThrough collaboration and an interdisciplinary team approach, leaders and staff developed and implemented a rapid assessment zone that reduced multiple throughput metrics. 相似文献
7.
目的 研究唇挡早期矫治上颌拥挤病例引起的牙弓三维改变.方法 选取正畸患者12例,平均年龄9.8岁.为缓解上颌的拥挤,戴用唇挡8个月.戴用唇挡前后取记存模型,进行三维数字化,以第三腭皱为参考将治疗前后的模型重叠,分析牙齿三维位置改变及倾斜度的变化.配对t检验比较治疗前后牙弓宽度和上牙弓弧形长度的差异.结果 戴用唇挡后,牙齿三维方向的改变以后部牙弓的变化最为显著,矢状向上颌第一前磨牙、第一磨牙分别远中移动2.08、2.03mm,上牙弓弧形长度增加5.12mm;垂直向上颌第一前磨牙升高1.17mm,第一磨牙升高0.72mm;横向上颌第一前磨牙间宽度增加2.62mm,第一磨牙间宽度增加3.08mm;以上各测量均有统计学意义(P<0.05).同时上颌切牙存在少量前移、扩宽和唇倾.上颌切牙唇倾度增加3.90°,第一磨牙远中倾斜度增加8.23,有显著性差异(P<0.05).结论 上颌唇挡可以缓解轻中度的牙弓拥挤.唇挡引起的牙弓长度增加主要是由于磨牙的远中移动、后倾以及牙弓的扩宽. 相似文献
8.
Crowding occurs when surrounding objects (flankers) impair target perception. A key property of crowding is the weaker interference when target and flankers strongly differ on a given dimension. For instance, identification of a target letter is usually superior with flankers of opposite versus the same contrast polarity as the target (the “polarity advantage”). High performance when target-flanker similarity is low has been attributed to the ungrouping of target and flankers. Here, we show that configural cues can override the usual advantage of low target-flanker similarity, and strong target-flanker grouping can reduce – instead of exacerbate – crowding. In Experiment 1, observers were presented with line triplets in the periphery and reported the tilt (left or right) of the central line. Target and flankers had the same (uniform condition) or opposite contrast polarity (alternating condition). Flanker configurations were either upright (||), unidirectionally tilted (\\ or //), or bidirectionally tilted (\/ or /\). Upright flankers yielded stronger crowding than unidirectional flankers, and weaker crowding than bidirectional flankers. Importantly, our results revealed a clear interaction between contrast polarity and flanker configuration. Triplets with upright and bidirectional flankers, but not unidirectional flankers, showed the polarity advantage. In Experiments 2 and 3, we showed that emergent features and redundancy masking (i.e. the reduction of the number of perceived items in repeating configurations) made it easier to discriminate between uniform triplets when flanker tilts were unidirectional (but not when bidirectional). We propose that the spatial configurations of uniform triplets with unidirectional flankers provided sufficient task-relevant information to enable a similar performance as with alternating triplets: strong-target flanker grouping alleviated crowding. We suggest that features which modulate crowding strength can interact non-additively, limiting the validity of typical crowding rules to contexts where only single, independent dimensions determine the effects of target-flanker similarity. 相似文献
9.
目的:通过测量牙弓宽度变化探讨Damon自锁托槽矫治安氏I类错(牙合)畸形的作用机制及疗效。方法:21例处于生长发育期的青少年安氏I类患者,采用Damon自锁托槽进行非拔牙矫治,治疗前后进行头影测量和牙弓宽度测量,分析牙弓宽度的变化特征。结果:矫治后患者牙列拥挤均解除,上、下颌牙弓宽度WU4、WU5、WU6、WL3、WL4、WL5、WL6在治疗后均明显增加(P<0.05)。上、下颌前牙治疗后唇倾度增加,UI-NA、LI-MP、LI-NB治疗前后差异均有统计学意义(P<0.05)。结论:Damon自锁托槽对于治疗安氏I类非拔牙矫治有特殊的疗效,可通过增加患者的牙弓宽度解除牙列拥挤,从而达到非拔牙矫治的效果。 相似文献
10.