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1.
Within triads of male Wistar rats, some animals almost completely abstain from competition for palatable sucrose pellets (so-called poor-performing rats), whereas other rats consistently win the competition (so-called high-performing rats). Subchronic (5 mg/kg; 5 consecutive days), but not acute (0.1–20 mg/kg), treatment with chlordiazepoxide temporarily helped poor-performing rats to behave more competitively. This finding, considered together with parallel studies (using high-performing rats), suggested that chloridazepoxide's beneficial effect was only demonstrable when the poor-performing rats had become tolerant to the drug's initial sedative effect. 相似文献
2.
A panel of synthetic peptides representing human lymphocyte antigen (HLA) B8, other class I and class II restricted T cell epitopes and two B cell epitopes, were all able to compete with recognition of a HLA B8 restricted epitope by a cytotoxic T cell clone. Competition was obtained when the competitor peptides were added either before or after the target epitope. The target epitope also had a slow off rate, implicating allosteric inhibition. The presence of non-specific, allosteric binding sites may interfere with experiments attempting to define immunologically relevant MHC binding specificities. 相似文献
3.
用杂交瘤技术建立三株分泌抗甲状腺球蛋白(TG)单克隆抗体的杂交瘤细胞株。所获三种单克隆抗体经兔抗小鼠IgG亚类、IgM及IgA血清鉴定表明,两种为IgG_1,一种为IgA;三种含单克隆抗体小鼠腹水的滴度(ELISA法)均为51200以上;以竞争性固相抗体结合试验测定它们对抗原决定簇的特异性差异,结果发现三种单克隆抗体的抗原结合部位是不同的,但对抗原的结合有一定的相互竞争抑制现象。 相似文献
4.
Many governments are trying to invent new types of 'internal' healthcare market that will expose health services to competitive pressures to innovate, contain costs, raise service quality, and respond better to consumer demands; but not expose them to 'market failures' which prejudice universal access to 'basic' health services. Policy debates in this area are muddled and constricted by a failure to differentiate the variants of internal market that are available. This article outlines a taxonomy of the main types of internal market: primary doctor purchasing; managed competition; competitive bidding; social insurance; and compulsory private insurance. It notes their main structural characteristics and differences. Although internal market reforms have been intended to support the commercialization of healthcare, the idea of designing new types of economic structure to avoid market failure in healthcare has wider and more radical implications than most policy-makers intend. 相似文献
5.
波特竞争战略与现代医院战略管理 总被引:11,自引:0,他引:11
通过对现代企业战略界所所推崇的波特竞争战略的探讨,简单波特的三种竞争战略,分析了随着我国市场经济的建立,开放改革的不断深入,医院战略管理所面临的困惑,根据我国现代医院管理的实际,提供了波特竞争战略对医院战略的一些启示。 相似文献
6.
在外科学总论实习教学中,通过举办基本技能比赛,将日常教学与比赛内容紧密结合,充分发挥教师与学生的主观能动性,促进学生的训练和学习.比赛后对学生的问卷调查以及比赛成绩与考试成绩的分析结果表明,比赛有助于提高学生的外科学基本技能. 相似文献
7.
徐娟 《中华医学教育探索杂志》2011,10(10):1213-1215
《组织学与胚胎学》考试方法进行了改革,试用了以竞赛型现场考试为特色,以态度考核及平时成绩为支撑的考试体系。其优点在于形式新颖、多样,激发热情、创新,富有人文关爱,且纳入了过程评价和结果评价,受到了学生欢迎。同时还注意到,应增大笔试比例来维持公平性。 相似文献
8.
9.
《Nutrition Clinique et Métabolisme》2014,28(4):272-278
Nutrition and physical training are the main determinants of performance in athletes. If physical training load increases, a change of diet, in reference to the usual dietary intake can be considered. This specific nutrition will be adapted to the basic nutritional rules in healthy subjects with two objectives: firstly, to ensure balance and restoration of the various losses induced by physical training (macro, micronutrients) and secondly, to bring the necessary supplements before, during and after the sport competition in a performance objective. The type of restoration will vary according to the type of sport and multiple parameters should be taken into account: predominant activity (endurance or strength), its intensity and duration. The nutrition strategy will be different during the sport competition and focused on the glucose reserve by promoting its availability during effort with the objective of performance increase. 相似文献
10.
We study gatekeeping physicians’ referrals of patients to specialty care. We derive theoretical results when competition in the physician market intensifies. First, due to competitive pressure, physicians refer patients to specialty care more often. Second, physicians earn more by treating patients themselves, so refer patients to specialty care less often. We assess empirically the overall effect of competition with data from a 2008–2009 Norwegian survey, National Health Insurance Administration, and Statistics Norway. From the data we construct three measures of competition: the number of open primary physician practices with and without population adjustment, and the Herfindahl–Hirschman index. The empirical results suggest that competition has negligible or small positive effects on referrals overall. Our results do not support the policy claim that increasing the number of primary care physicians reduces secondary care. 相似文献