全文获取类型
收费全文 | 3103篇 |
免费 | 351篇 |
国内免费 | 52篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 51篇 |
妇产科学 | 139篇 |
基础医学 | 400篇 |
口腔科学 | 46篇 |
临床医学 | 307篇 |
内科学 | 348篇 |
皮肤病学 | 32篇 |
神经病学 | 177篇 |
特种医学 | 228篇 |
外科学 | 165篇 |
综合类 | 182篇 |
预防医学 | 737篇 |
眼科学 | 25篇 |
药学 | 482篇 |
3篇 | |
中国医学 | 75篇 |
肿瘤学 | 98篇 |
出版年
2024年 | 7篇 |
2023年 | 63篇 |
2022年 | 83篇 |
2021年 | 140篇 |
2020年 | 118篇 |
2019年 | 115篇 |
2018年 | 137篇 |
2017年 | 114篇 |
2016年 | 116篇 |
2015年 | 156篇 |
2014年 | 188篇 |
2013年 | 234篇 |
2012年 | 156篇 |
2011年 | 187篇 |
2010年 | 136篇 |
2009年 | 157篇 |
2008年 | 152篇 |
2007年 | 153篇 |
2006年 | 119篇 |
2005年 | 100篇 |
2004年 | 85篇 |
2003年 | 76篇 |
2002年 | 83篇 |
2001年 | 60篇 |
2000年 | 41篇 |
1999年 | 42篇 |
1998年 | 52篇 |
1997年 | 65篇 |
1996年 | 43篇 |
1995年 | 30篇 |
1994年 | 43篇 |
1993年 | 26篇 |
1992年 | 30篇 |
1991年 | 24篇 |
1990年 | 26篇 |
1989年 | 19篇 |
1988年 | 24篇 |
1987年 | 21篇 |
1986年 | 10篇 |
1985年 | 26篇 |
1984年 | 10篇 |
1983年 | 3篇 |
1982年 | 7篇 |
1981年 | 6篇 |
1980年 | 2篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1977年 | 5篇 |
1975年 | 4篇 |
1974年 | 2篇 |
排序方式: 共有3506条查询结果,搜索用时 62 毫秒
1.
Jeroen M. van de Pol Jurjen G. Geljon Svetlana V. Belitser Geert W.J. Frederix Anke M. Hövels Marcel L. Bouvy 《Research in social & administrative pharmacy》2019,15(1):70-76
Introduction
The nature of community pharmacy is changing, shifting from the preparation and distribution of medicines to the provision of cognitive pharmaceutical services (CPS); however, often the provision of traditional services leaves little time for innovative services. This study investigated the time community pharmacists spend on the tasks and activities of daily practice and to what extent they are able to implement CPS-related services in daily practice.Methods
Self-reporting work sampling was used to register the activities of community pharmacists. A smartphone application, designed specifically for this purpose, alerted participants to register their current activity five times per working day for 6 weeks. Participants also completed an online survey about baseline characteristics.Results
Ninety-one Dutch community pharmacists provided work-sampling data (7848 registered activities). Overall, 51.5% of their time was spent on professional activities, 35.4% on semi-professional activities, and 13.1% on non-professional activities. The proportion of time devoted to CPS decreased during the workweek, whereas the time spent on traditional task increased.Discussion and conclusion
This study shows it is feasible to collect work-sampling data using smartphone technology. Community pharmacists spent almost half of their time on semi-professional and non-professional activities, activities that could be delegated to other staff members. In practice, the transition to CPS is hampered by competing traditional tasks, which prevents community pharmacists from profiling themselves as pharmaceutical experts in daily practice. 相似文献2.
Mhamed 《Computerized medical imaging and graphics》2006,30(8):447-451
The aim in this work is to report a new method to calculate parametric images from a single scan acquisition with positron emission tomography (PET) and fluorodeoxyglucose (FDG) in the human brain without blood sampling. It is usually practical for research or clinical purposes to inject the patient in an isolated room and to start the PET acquisition only for some 10–20 min, about 30 min after FDG injection. In order to calculate the cerebral metabolic rates for glucose (CMRG), usually several blood samples are required. The proposed method considers the relation between the uptake of the tracer in the cerebellum as a reference tissue and the population based input curve. Similar results were obtained for CMRG values with the present method in comparison to the usual autoradiographic and the non-linear least squares fitting of regions of interest. 相似文献
3.
建立了顶空毛细管GC法测定吉非罗齐中甲酸乙酯、THF和甲基环己烷3种有机溶剂的残留量。采用HP-1毛细管柱,溶剂DMA,内标乙酸乙酯。平均同收率分别为99.8%、100.3%、100.0%,RSD分别为0.71%、1.51%和1.76%。 相似文献
4.
Summary It has been widely observed that the outcome after repeat lumbar surgery is rarely comparable to that of primary surgery. In particular, the results of repeat surgery for lumbar spinal stenosis (LSS) have not been favourable. We used a matched-pair format in an attempt to decrease the confounding factors so as to determine as exactly as possible the effect of prior back surgery on the LSS patients surgical outcome. The matching criteria were sex, age, myelographic findings, major symptom, and duration of symptoms. From one group of 251 patients without prior back surgery (SO patients) and another of fifty-three patients with one preceding back operation (RS patients), forty-one similar matched patients pairs (one SO and one RS-patient) were formed.There were 8 female and 33 male pairs. The mean age of the SO patients was 51.6 and of the RS patient 51.4 years, and the mean follow-up time was 4.6 and 4.4 years. The assessment of outcome was based on a subjective disability questionnaire. The SO patients fared significantly better than the RS patients (32.1 versus 41.3, P = 0.026). A short time interval between operations in the RS patients had a worsening effect on outcome, but this trend was not significant.We concluded that one preceding back operation had a worsening effect on the outcome of patients operated on for LSS. As a whole, the results of RS patients were unfavourable. The proper time for achieving good surgical results in LSS patients is the initial operation. 相似文献
5.
E. Stermer J. Bejar† I. Miselevich† O. Goldstein D. Keren A. Lavy J. H. Boss† D. Keren 《Colorectal disease》2005,7(4):345-349
BACKGROUND: Total excision of colonic polyps is not always attainable and in some patients it is clinically contraindicated. Also, a resected polyp may be lost at any step between its endoscopic removal and its embedding in paraffin. The aim of this study was to compare the histological features of colonic polyps as analysed by the study of biopsy-forceps obtained samples with those assessed on scrutinizing the totally resected growths. PATIENTS AND METHODS: This prospective study included a cohort of 59 patients in whom, in the course of an elective colonoscopy, a total excision of a 6 mm-sized or larger polyp was called for. Sizeable biopsies were obtained by means of an Olympus Multibyte forceps prior to the total polypectomy. Subsequent to the study of the polypectomy specimens, the forceps biopsy samples were submitted for histological examination. The pathologists were blinded as to the source of the tissue they were studying. The diagnoses rendered by evaluating the biopsy samples and polypectomy specimens of each patient were contrasted with each other. RESULTS: Major discrepancies between the histological features of the fragments captured by the biopsy-forceps and the factual nature of the totally removed polyps were uncovered in 11 (18.6%) of 59 cases. Intriguingly, the grade of the tumours was underrated in all the 11 cases, as judged by contrasting the tentative diagnoses of the forceps-biopsies with the decisive diagnoses of the polypectomies. Importantly, 2 adenocarcinomas would have been missed by just looking at the forceps-retrieved sample. CONCLUSIONS: In our experience, a discordance of 18.6% is to be expected between the diagnoses rendered after examining forceps-biopsies of and totally excised colonic polyps. Nevertheless, it is advisable to procure biopsies prior to the excision of the growths, because on those occasions in which patients' growths cannot be removed or have not been retrieved for one reason or another, a small forceps-captured tissue sample correctly reflects the characteristics of the polyp in 81.4% of the cases. Finally, the biopsies may be discarded in the event that total removal was successful. 相似文献
6.
7.
Takanobu Anai M.D. Isao Miyakawa M.D. Ph.D. Hiromi Ohki M.D. Teruyuki Ogawa M.D. Ph.D. 《Pediatrics international》1992,34(3):324-327
There have been only 2 previous reports of nonimmunologic hydrops fetalis (NIHF) caused by fetal Kasabach-Merritt syndrome, both of which were pathological studies. This is the first clinical case report of NIHF due to fetal Kasabach-Merritt syndrome that was prenatally diagnosed by sonography, computerized tomography, and percutaneous umbilical blood sampling. 相似文献
8.
Stuart A. Batterman Alfred Franzblau Nanzheng Zhou 《International archives of occupational and environmental health》1996,68(4):268-274
Dermal exposures of methanol were administered in a clinical study designed to compare several biological indicators. Four
subjects were exposed in five exposure sessions of varying length. In each session, a sequence of measurements of methanol
concentrations in blood, breath, and headspace samples of air at exposed and unexposed skin were collected before and after
dermal exposures. Skin headspace samples, collected in gas sampling bags, were designed to reflect equilibrium skin: air partitioning.
At exposed skin, headspace samples were highly elevated for at least 8 h following exposure, indicating the presence of a
methanol reservoir in skin. After exposure, methanol concentrations at exposed skin showed a rapid initial decline, then a
slower first-order decrease. Methanol concentrations were clearly detectable in headspace samples at unexposed skin. Substantial
transfer from exposed skin occurred due to mechanical contact and washing. When transfer was restricted, surface concentrations
at unexposed skin were similar to levels in breath and were strongly correlated to methanol concentrations in blood. While
results are preliminary due to the small sample sizes and several unresolved experimental issues, the simple, rapid, and noninvasive
skin headspace measurements appear useful as a biological exposure indicator that clearly shows the presence and site of a
dermal exposure, and measurements at unexposed skin reflect concentrations in blood.
Received: 14 March 1995/Accepted: 3 November 1995 相似文献
9.
The Design and Analysis of Hospital Utilization Studies 总被引:1,自引:1,他引:0
10.
H. Seyer J. Honegger W. Schott M. Küchle W. J. Huk R. Fahlbusch H. Frisch 《Acta neurochirurgica》1994,131(1-2):157-159
Summary Inferior petrosal sinus sampling (IPSS) is used to evaluate the pituitary-dependency of Cushing's disease, and to predict the laterality of a microadenoma prior to transsphenoidal operation. A serious complication occured in a 14-year-old boy: he suffered brain stem ischaemia with abducens nerve palsy and hemiparesis (Raymond's syndrome). The case prompted us to reconsider the indication for this investigation. 相似文献