淋巴管型着色芽生菌病1例

52岁男性农民，左手臂沿淋巴管排列损害4年。损害由结节和时间 红色浸润斑块覆污秽色痂组成，部分损害表面有黑点。临床表现酷似淋巴管型孢子丝菌病。直接镜检和组织病理见棕色厚壁孢子，培养证实病原菌为卡氏支孢霉。诊断为卡氏支孢霉所致皮肤着色芽生菌病。     

ENDOSCOPIC OBSERVATION OF MUCOSAL SPREAD LESION OF CHOLANGIOCARCINOMA USING PERORAL CHOLANGIOSCOPY WITH NARROW BAND IMAGING

A 69‐year‐old man was admitted to Toho University Omori Medical Center complaining of icterus. Abdominal computed tomography, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography were suspicious of cholangioma of inferior bile duct. Peroral cholangioscopy using narrow band imaging (NBI) was performed and it was possible to diagnose the mucosal spread lesions of cholangioma. Histological findings reflected the endoscopic findings. Mucosal spread lesions of cholangiocarcinoma were successfully diagnosed using the CHF‐B260 for NBI.     

Leptomeninges as a site of relapse in locally controlled,diffuse pontine glioma with review of literature

Case report Leptomeningeal involvement in diffuse intrinsic brain stem gliomas is rarely diagnosed clinically and in majority of the instances diagnosed only on postmortem examination. We report two cases of diffuse pontine glioma diagnosed clinicoradiologically and treated with conventional radiotherapy.Observations On follow-up, both patients showed clinical features suggestive of meningeal spread although imaging for pontine tumor showed stable disease. Leptomeningeal disease in the spine was confirmed on imaging and in one case by cerebrospinal fluid examination also. During the follow-up of patients with pontine glioma, the possibility of leptomeningeal involvement must be borne in mind.     

RF refocused echoes of J-coupled spin systems: effects on RARE-based spectroscopic imaging.

A numerical simulation tool was developed to calculate the echo amplitudes of J-coupled resonances within a series of radiofrequency (RF) refocused echoes. The signal modulation due to J-coupling in rapid acquisition with relaxation enhancement (RARE) is suppressed only when the inverse of the pulse interval (tau) is large compared to both the chemical shift (CS) difference (Deltadelta) of the coupled spins and the coupling constant. In contrast, the echo amplitudes in ultrafast low-flip-angle RARE (U-FLARE) oscillate around a quasi-steady-state value that is greater than zero (neglecting relaxation and diffusion) even when Deltadelta > 1/tau. The flip-angle distribution over the measured slice caused by the use of Gaussian-shape slice-selective refocusing pulses further reduces the echo oscillations. When the pulse interval falls short of the fast pulse rate regime, spectroscopic U-FLARE provides an improved spatial impulse response in the phase-encoding (PE) direction compared to spectroscopic RARE.     

艾滋病与千年发展目标

通过艾滋病的流行和传播与其他发展目标的相互影响,论证遏制并扭转艾滋病蔓延的紧迫性,同时采取多途径确保千年发展目标的最终实现。     

Ovine scrapie: Follow-up of sheep belonging to an endemic scrapie-infected flock

There is a close similarity between the unconventional virus-induced ovine scrapie and human Creutzfeldt-Jakob disease. Since infection might be transmitted orally, the ovine production of an endemically scrapie-infected farm was studied. About 80% of the annual production are sold (50% as butcher-meat, 30% as breeding animals), and scrapie appears in 20% of the sheep kept on the farm. Was the same proportion of butcher-meat animals scrapie-infected? Since the scrapie agent has been detected in “clinically normal” lambs, the same problem occurs with breeding-sheep and “apparently healthy” animals: are they carriers of the pathogenic agent? Are they responsible for the spread of the ovine disease and/or of the human disease?     

Measurement of current spread from microelectrodes when stimulating within the nervous system

Summary Tungsten stimulating microelectrodes have been tested in monopolar, bipolar and concentric configurations for the extent to which unwanted current spread occurred. Current spread from monopolar electrodes in close conformity with the predictions of the inverse square law, both in vitro and in vivo. The bipolar and concentric configurations, tested only in vitro, had current-spread characteristics which did not follow the inverse square law so closely. The bipolar configuration gave little reduction in spread, compared with a monopolar electrode, but the concentric configuration did reduce the extent of stimulus spread. The extent of spread depends greatly upon a number of experimental variables, including the dimensions of the microelectrode tip. For studies requiring precise localization, with low stimulus currents, it is advisable to determine the inverse square law constant for each experimental situation. For more generalized stimulation purposes within the mammalian C.N.S., employing monopolar microelectrodes of moderate tip size, brief pulses of 10 A can be expected to stimulate myelinated axons within about 0.15 mm of the tip, and 100 A will stimulate within a radius of about 0.5 mm.The work was all done while E.V.B. was on Industrial Training leave from the North-East Polytechnic, Romford Road, London E. 15     

装饰纹样的背景与传播

以比较美学的方法,有选择地比较和阐述了世界各地装饰纹样的起源背景、各自特点以及它们之间的相互影响。认为各民族、各地区的装饰艺术存在着相通中有不同、不同中有相通的关系,为现代艺术设计者带来了继承和变化的资源,同时也为体味和享受异域装饰美提供了理解的通道。     

12所商务楼德国小蠊侵害及扩散原因分析初报

目的　了解上海商务楼内德国小蠊侵害及扩散的原因。方法　用 0 .3 %二氯苯醚菊酯酒精液药激法调查 ,每隔一层随机调查 5间办公室 ,如遇到餐饮、面包咖啡馆的层面 ,则需调查该层和上下相邻的两层 ,并作好记录。结果　 12所商务楼中德国小蠊侵害率为 5 8.3 3 %。结论　德国小蠊主要是通过机械性携带传入商务楼 ,在商务楼内通过中央空调管道和厨房间的地漏逐渐向周围蔓延。