全文获取类型
收费全文 | 2028篇 |
免费 | 66篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 49篇 |
妇产科学 | 68篇 |
基础医学 | 267篇 |
口腔科学 | 36篇 |
临床医学 | 406篇 |
内科学 | 220篇 |
皮肤病学 | 6篇 |
神经病学 | 215篇 |
特种医学 | 19篇 |
外科学 | 179篇 |
综合类 | 80篇 |
一般理论 | 10篇 |
预防医学 | 380篇 |
眼科学 | 6篇 |
药学 | 71篇 |
1篇 | |
中国医学 | 14篇 |
肿瘤学 | 76篇 |
出版年
2024年 | 28篇 |
2023年 | 139篇 |
2022年 | 137篇 |
2021年 | 208篇 |
2020年 | 148篇 |
2019年 | 96篇 |
2018年 | 115篇 |
2017年 | 89篇 |
2016年 | 61篇 |
2015年 | 49篇 |
2014年 | 74篇 |
2013年 | 141篇 |
2012年 | 77篇 |
2011年 | 50篇 |
2010年 | 44篇 |
2009年 | 72篇 |
2008年 | 90篇 |
2007年 | 78篇 |
2006年 | 70篇 |
2005年 | 49篇 |
2004年 | 60篇 |
2003年 | 56篇 |
2002年 | 33篇 |
2001年 | 29篇 |
2000年 | 23篇 |
1999年 | 13篇 |
1998年 | 10篇 |
1997年 | 15篇 |
1996年 | 10篇 |
1994年 | 9篇 |
1993年 | 4篇 |
1992年 | 4篇 |
1991年 | 1篇 |
1990年 | 6篇 |
1988年 | 3篇 |
1987年 | 6篇 |
1986年 | 1篇 |
1985年 | 3篇 |
1984年 | 4篇 |
1980年 | 1篇 |
1979年 | 3篇 |
排序方式: 共有2109条查询结果,搜索用时 0 毫秒
1.
Studies from the last decade on factors influencing reproductive planning after genetic counselling were reviewed. Increased possibilities of DNA-analysis and prenatal diagnosis might have brought about a shift in the paramountcy of factors influencing reproductive planning after genetic counselling. In contrast to the literature in the seventies, the magnitude of the genetic risk was no longer found to be one of the decisive factors in postcounselling reproductive planning. Instead, the interpretation of the risk as high or low and the desire to have children appeared to be paramount. The impact of new developments in DNA-analysis in prenatal diagnosis and presymptomatic testing will be an important subject for future studies on factors influencing reproductive planning. 相似文献
2.
The uptake of contralateral prophylactic mastectomy (CPM) has increased steadily over the last twenty years in women of all age groups and breast cancer stages. Since contralateral breast cancer is relatively rare and the breast cancer guidelines only recommend CPM in a small subset of patients with breast cancer, the drivers of this trend are unknown. This review aims to evaluate the evidence for and acceptability of CPM, data on patient rationales for choosing CPM, and some of the factors that might impact patient preferences. Based on the evidence, future recommendations will be provided. First, data on contralateral breast cancer risk and CPM rates and trends are addressed. After that, the evidence is structured around four main patient rationales for CPM formulated as questions that patients might ask their surgeon: Will CPM reduce mortality risk? Will CPM reduce the risk of contralateral breast cancer? Can I avoid future screening with CPM? Will I have better breast symmetry after CPM? Also, three different guidelines regarding CPM will be reviewed. Studies indicate a large gap between patient preferences for radical risk reduction with CPM and the current approaches recommended by important guidelines. We suggest a strategy including shared decision-making to enhance surgeons’ communication with patients about contralateral breast cancer and treatment options, to empower patients in order to optimize the use of CPM incorporating accurate risk assessment and individual patient preferences. 相似文献
3.
Martijn Felder Hester van de Bovenkamp Willem Jan Meerding Antoinette de Bont 《Health policy (Amsterdam, Netherlands)》2021,125(1):34-40
We critically examine the discussion on the role of evidence-based medicine (EBM) in healthcare governance. We take the institutionally layered Dutch healthcare system as our case study. Here, different actors are involved in the regulation, provision and financing of healthcare services. Over the last decades, these actors have related to EBM to inform their actor specific roles. At the same time, EBM has increasingly been problematised. To better understand this problematisation, we organised focus groups and interviews. We noticed that particularly EBM’s reductionist epistemology and its uncritical use by ‘professional others’ are considered problematic. However, our analysis also reveals that something else seems to be at stake. In fact, all the actors involved underwrite EBM’s reductionist epistemology and emphasise that evidence should be contextualised. They however do so in different ways and with different contexts in mind. Moreover, the ways in which some actors contextualise evidence has consequences for the ways in which others can do the same. We therefore emphasise that behind EBM’s scientific problematisation lurks a political issue. A dispute over who should contextualise evidence how, in a layered healthcare system with interdependent actors that cater to both individual patients and the public. We urge public administration scholars and policymakers to open-up the political confrontation between healthcare actors and their sometimes irreconcilable, yet evidence-informed perspectives. 相似文献
4.
Martin Geisler Carl Martin Allwood Ilkka Salo 《Health & social care in the community》2021,29(5):1473-1482
Social insurance administrative officers’ decision-making skills influence their efficiency at work and their general well-being. At work their tasks are characterised by complexity and a need for order and accountability. Moreover, cases should usually be handled and finalised within the imposed time frames. We investigated skills related to decision-making success among social insurance officers. In total, 118 administrative officers at the Swedish Social Insurance Agency (66% response rate) responded to questions on scales and measures relating to cognitive-rational, socio-emotional and time approach features of decision-making skill. In addition, they responded to questions on three scales pertaining to outcomes of everyday decisions in terms of subjective everyday difficulties, tendencies to burnout and depressive symptoms. The results showed that cognitive-rational competence was associated with lower reports of subjective everyday difficulties and depressive symptoms and thereby contributed to the explained variance in decision outcomes. Furthermore, socio-emotional and time approach features of decision-making skills contributed to the explanation for subjective everyday difficulties, tendencies to burnout and depressive symptoms. The results corroborate the basic assumption and usefulness of a broad approach in the definition and assessment of decision-making skills in human service professions in general, and of administrative officers in social insurance agencies in particular. Recommendations for future research and the implications of the results are discussed. 相似文献
5.
Herman Nys Sander Welie Tina Garanis-Papadatos Dimitris Ploumpidis 《Health care analysis》2004,12(4):329-337
The discriminatory effects of categorizing psychiatric patients into competent and incompetent, have urged lawyers, philosophers and health care professionals to seek a functional approach to capacity assessment. Dutch and English law have produced some guidelines concerning this issue. So far, most legal systems under investigation have concentrated on alternatives for informed consent by the patient in case of mental incapacity, notably substitute decision-making, intervention of a judge and advance directives. It is hard to judge the way in which the law may further adapt to a more functional assessment of capacity, because the nature of law shows that legal reforms usually take place only when new methods have been accepted by the field. This is not yet the case today. 相似文献
6.
Stephen R. Kraus Junlong Li Rita M. Kristy Amy Lockefeer Hongbo Yang Mo Zhou David R. Walker 《The Journal of international medical research》2022,50(5)
ObjectiveTo understand factors guiding overactive bladder (OAB) therapy selection and experience with combination therapy (antimuscarinics and beta-3 agonists).MethodsCross-sectional surveys of OAB patients and OAB-treating physicians in the USA were conducted. Patients receiving monotherapy with antimuscarinics were categorized by OAB treatment history: monotherapy only; third-line procedures (e.g., onabotulinumtoxinA injections) and combination therapy; third-line therapy only; and combination therapy only. The patient survey assessed therapy choice drivers and barriers, treatment satisfaction and sociodemographic/clinical characteristics. The physician survey assessed drivers of and barriers to OAB treatment choices.ResultsOf 200 patients, 86.5% reported involvement in treatment decision-making; doctor’s recommendation was the most frequently considered factor (84.4%). Most patients (71%) were unaware of combination therapy. The primary reason why those patients aware of combination therapy had not used it (N = 43/200; 21%) was physician recommendation of other treatments (69.8%). For physicians (N = 50), the most frequently considered factors when prescribing OAB treatment were effectiveness (92.0%) and side effects (84.0%); 70% prescribed combination therapy, primarily for symptom severity (82.9%). The main reasons for not prescribing combination therapy were cost/insurance coverage (80%) and lack of information (53.3%).ConclusionsShared decision-making guided treatment decisions; the main considerations were treatment safety and efficacy. 相似文献
7.
Hilmar H. Bijma Agnes van der Heide Hajo I. J. Wildschut 《European Clinics in Obstetrics and Gynaecology》2007,3(2):89-95
During the last few decades, the use of ultrasonography for the detection of fetal abnormalities has become widespread in
many industrialised countries. This resulted in a shift in timing of the diagnosis of congenital abnormalities in infants
from the neonatal period to the prenatal period. This has major implications for both clinicians and the couples involved.
In case of ultrasound diagnosis of fetal anomaly, there are several options for the obstetric management, ranging from standard
care to non-aggressive care and termination of pregnancy. This essay explores the context of both clinical and parental decision
making after ultrasound diagnosis of fetal abnormality, with emphasis on the Dutch situation. While normal findings at ultrasound
examination have strong beneficial psychological effects on the pregnant woman and her partner, the couple is often ill prepared
for bad news about the health of their unborn child in the case of abnormal findings. This is, in particular, true in settings
where ultrasonography for the detection of fetal abnormalities is offered as an integral part of antenatal care without appropriate
counselling. An important question is to what extent the couple should be supported in decision making when a fetal abnormality
is diagnosed. In this context, the parental perception of having a choice varies markedly. When parents consider end-of-life
decisions, they experience both ambivalent and emotional feelings. On the one hand, they are committed to their pregnancy,
while on the other hand, they want to protect their child, themselves and the family from the burden of severe disability.
These complex parental reactions have implications for the counselling strategy.
相似文献
Hajo I. J. WildschutEmail: |
8.
Xinmu Hu Yu Zhang Xiaoqing Liu Yunfei Guo Chao Liu Xiaoqin Mai 《Social cognitive and affective neuroscience》2022,17(8):695
Neuroimaging studies suggest that the right dorsolateral prefrontal cortex (rDLPFC) is an important brain area involved in fairness-related decision-making. In the present study, we used transcranial direct current stimulation (tDCS) over the rDLPFC to investigate the effects of changed cortical excitability on fairness norm enforcement in social decision-making. Participants received anodal, cathodal or sham stimulation before performing a modified ultimatum game task, in which participants were asked to accept or reject the proposer’s offer and self-rate the intensity of their anger at offers on a 7-point scale. The results showed that the rejection rate of unfair offers and anger level were higher in the anodal compared to the sham and cathodal groups and that the level of anger at unfair offers can predict the rejection rate. Furthermore, the fairness effect of RTs was more prominent in the anodal group than in the sham and cathodal groups. Our findings validate the causal role of the rDLPFC in fairness-related decision-making through tDCS, suggesting that strengthening the rDLPFC increases individuals’ reciprocal fairness in social decision-making, both in subjective rating and behaviors. 相似文献
9.
《Gerontology & geriatrics education》2013,34(1):15-16
No abstract available for this article. 相似文献
10.
《Vulnerable children and youth studies》2013,8(4):321-329
This article explores the constraints and opportunities in children's decision-making in child-headed households (CHHs). It draws from the findings of an explorative study of 30 CHHs carried out in Harare, Zimbabwe in 2007. Relatively little is known about how children make decisions in CHHs, notwithstanding the fact that understanding this process can be an entry way into their lifeworlds. Situated semi-structured interviews were used with older children from the ages of 11–17 years and participatory methods with children from the ages of 5–10 years to investigate decision-making in CHHs. The findings seem to reveal that some of the children in CHHs are active agents who try in their own way to make sense of their situations and to act within their capacities to improve their experiences. Initiatives to assist them should therefore be planned, taking into account the fact that they can contribute solutions to the challenges they encounter in their daily lives. 相似文献