自制口腔护理液对手足口病患儿口腔疱疹的治疗效果分析

目的探析自制口腔护理液在手足口病患儿口腔疱疹中的应用效果。方法选取2017年6月至2018年10月郑州大学附属儿童医院感染科收治的136例手足口病患儿作为研究对象,按照随机数表法将其随机分为观察组(68例)与对照组(68例),其中观察组患儿采用本院自制的口腔护理液(维生素B_2粉末50 mg+1%利多卡因0.5 mL+生理盐水0.5 mL)涂擦口腔疱疹处,对照组患儿采用西瓜霜喷剂喷涂口腔疱疹处,对比观察两组患儿的口腔疼痛缓解时间、疱疹消退时间、住院时间及临床疗效。结果观察组患儿口腔疼痛缓解时间、口腔疱疹消退时间及住院时间均明显短于对照组,差异具有统计学意义(t'=17.060、19.430、13.570,P=0.000、0.000、0.000);观察组患儿治疗总有效率为97.06%,明显优于对照组患儿的治疗总有效率85.29%,差异具有统计学意义(χ~2=5.849,P=0.016)。结论自制口腔护理液用于手足口病患儿的口腔疱疹治疗,可有效缓解口腔疼痛,促进疱疹消退,疗效确切,值得临床推广应用。     

贝复新凝胶治疗复发性阿弗他溃疡的临床疗效观察

目的 贝复新凝胶治疗复发性阿弗他溃疡的临床疗效。方法 选取临床就诊的112例复发性阿弗他溃疡患者,随机分成2组,每组各56例,观察组给予复方氯己定含漱+贝复新凝胶局部涂抹,对照组给予复方氯己定含漱+西瓜霜喷剂。比较2组局部治疗效果及平均症状消退和平均治愈时间。结果 观察组经治疗后局部症状消退时间和平均治愈时间明显缩短,无不良反应,局部治疗效果优于对照组（P<0.01）。结论 贝复新凝胶治疗复发性阿弗他溃疡疗效显著安全可靠,值得临床进一步推广和应用。     

西瓜霜喷剂治疗溃疡期压疮的疗效观察

目的探讨西瓜霜喷剂治疗溃疡期压疮的疗效。方法将30例溃疡期(Ⅲ期)压疮(院外带入)患者随机分为治疗组和对照组,治疗组用西瓜霜喷剂均匀地喷洒已清洗的创面,以药粉能被吸附为度,待药粉慢慢被浸湿后再次喷洒,如此反复,直至药粉不被浸湿为止(西瓜霜粉末持续黏附在创面上);对照组用红外线灯照射已清洗的创面20min,然后覆盖无菌纱块,2次/d。结果两组患者的疗效比较,治疗组明显优于对照组,具有显著性差异(uc=47,P<0.01)。治疗组的有效率明显高于对照组(χ2=4.66,P<0.05),差异具有统计学意义。结论用西瓜霜喷剂治疗溃疡期压疮,组织修复、创面愈合快,无疼痛,无刺激,无需包扎,较快控制感染,操作简单,价格低廉,安全,治愈率高。     

Removal of reactive yellow 145 by adsorption onto treated watermelon seeds: Kinetic and isotherm studies

The aim of this study is to valorize the watermelon seeds treated with hexane for the removal of reactive yellow 145 from aqueous solutions. The effects of physico-chemical parameters such as pH, adsorbent dose, temperature and dye concentration on the removal of dyes were evaluated. The kinetic study of the adsorption of reactive yellow 145 on watermelon seeds adsorbent perfectly followed the pseudo-second-order kinetic model. The Langmuir, Freundlich, Temkin, Elovich and Dubinin-Radushkevich models were studied. It was proved that the experimental data fitted well to the Freundlich model, which signifies that the phenomenon of adsorption is done in multilayers on heterogeneous surfaces. The finding of this paper asserts that this material is a good and low-cost adsorbent that can be used for the removal of dyes from aqueous solutions.     

Endoscopic ultrasound appearance of watermelon stomach

Gastric antral vascular ectasia (GAVE) seen endoscopically has characteristic thickened, red vascular folds radiating from the pylorus to the antrum. The endoscopic ultrasound findings are described and correlated with the visual appearance, computed tomographic (CT) scans, and histologic findings. Hyperechoic focal thickening of the inner layers of the gastric wall are noted and may reflect the diagnosis of GAVE.     

Fecal Impaction in Adults: Report of 30 Cases of Seed Bezoars in the Rectum

Purpose Seed bezoars in the rectum have been considered an uncommon cause of fecal impaction in adults. Although there have been several reports on sunflower seed bezoars, seed bezoars from the fruit of the prickly pear cactus and watermelon have received little notice. This study was designed to determine the frequency of fecal impaction by seed bezoars in the rectum and their clinical characteristics in adults. Methods A retrospective review of the medical records of patients hospitalized with the diagnosis of fecal impaction during a ten-year period. Results During the study period (January 1996 to December 2005), 55 patients were hospitalized at the Western Galilee Hospital, in northern Israel, with the diagnosis of fecal impaction. Phytobezoars were found in 30 patients (55 percent). The seed bezoars were composed of prickly pear seeds in 12 patients, watermelon seeds in 10 patients, sunflower seeds in 4 patients, popcorn kernels in 1 patient, and pomegranate seeds in 1 patient. The Jew:Arab ratio for seed bezoars was 7:23. Seventy-three patients had seedless fecal masses with a Jew:Arab ratio of 58:15. All 30 patients with bezoar underwent digital disimpaction under general anesthesia. Only 21 of 73 patients with seedless fecal masses were treated under general anesthesia. Conclusions Seed bezoars found in the rectum were the most common cause of fecal impaction requiring hospitalization, probably to the result of the eating habits in the Middle East. The consumption of seeds with shell fragments or fruits containing many seeds (such as the prickly pear) should be accompanied by the awareness that large quantities may cause fecal impaction. The Department of Surgery at Western Galilee Hospital is affiliated with the Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.     

Analysis of the biological and molecular variability of Watermelon mosaic virus isolates from Iran

Watermelon mosaic virus (WMV) is one of the most important viruses that causes different symptoms in Cucurbitaceae. WMV is a potyvirus with a worldwide distribution, but occurs most commonly in temperate and Mediterranean regions. Cucurbit species grown in Yazd, Esfahan, West Azerbaijan, Hormozgan, and Kerman provinces were surveyed for the relative incidence of WMV in 2004–2005. A total of 757 symptomatic cucurbit and 31 weed species were collected and assayed for infection with WMV. Of 788 leaf samples from cucurbit and weed plants, 190 samples were positive by double antibody sandwich ELISA (DAS-ELISA) using specific polyclonal antibody. Among the weed species tested only colocynth (Citrullus colocynthis) was found to be infected with WMV. The coat protein (CP) gene from 18 representative isolates was PCR amplified, cloned, sequenced, and compared with the sequences available in GeneBank. Phylogenetic analysis using 778 nucleotide long sequences of the coat protein gene showed that these isolates fell into two; groups I and II. Only one isolates (KER.JI.1) was classified in the group II. This isolate had a wider host range and infected Nicotiana debneyii and Datura metel. None of the other 17 isolates could infect these two species. Members of group I were divided into three subgroups; A, B, and C. The subgroup I_B appears to be a new subgroup comprising only of the Iranian isolates. Phylogenetic analysis based on 200 nucleotides coding for the N-terminal segment of the CP showed that all Iranian isolates except KER.JI.1 clustered with the previously reported WMV strains. All Iranian isolates had a DAG amino acid triplet which is involved in aphid transmissibility. This is the first report on sequence analysis of the nearly full-length CP cDNA clones of WMV isolates from Iran.     

Modulating Oxidative Stress and Inflammation in Elders: The MOXIE Study

Cardiovascular disease (CVD) is the leading cause of death among women in the United States. Endothelial dysfunction and arterial stiffness increase with advancing age and are early predictors of future CVD outcomes. We designed the Modulating Oxidative Stress and Inflammation in Elders (MOXIE) study to examine the effects of 100% watermelon juice as a “food-first” intervention to reduce CVD risk among African American (AA) and European American (EA) women aged 55–69 years. Vascular dysfunction is more pronounced in AA compared to EA women due in part to lower nitric oxide bioavailability caused by higher oxidative stress. However, bioactive compounds in watermelon may improve vascular function by increasing nitric oxide bioavailability and antioxidant capacity. This trial will use a randomized, placebo-controlled, crossover design to investigate the potential of 100% watermelon juice to positively impact various robust measures of vascular function as well as serum biomarkers of oxidative stress and antioxidant capacity. This nutrition intervention and its unique methodology to examine both clinical and mechanistic outcomes are described in this article.     

微波联合西瓜霜喷剂治疗45例宫颈糜烂的临床疗效分析

目的：探究与分析微波联合西瓜霜喷剂治疗宫颈糜烂的临床疗效。方法选取2012年10月—2014年10月该院收治的宫颈糜烂患者90例,随机分为对照组和试验组,各45例。对照组仅给予微波治疗,试验组在其基础上加用西瓜霜喷剂治疗,对比两组患者临床疗效、阴道出血量及阴道排液时间。结果试验组与对照组总有效率相比差异有统计学意义（χ2=4.35,P<0.05）。试验组与对照组阴道出血量与阴道排液时间相比,差异有统计学意义（t=3.56,P<0.05;t=3.11,P<0.05）。结论微波联合西瓜霜喷剂治疗宫颈糜烂的临床疗效显著,明显减少阴道出血量,缩短阴道排液时间,值得推广。