Ureteritis cystica: A rare benign lesion

Ureteritis cystica is an uncommon benign pathology of the ureter. The etiology is unclear but the diagnosis has become much easier to make with the routine use of ureteroscopy for diagnosis of ureteric lesions. We present a case of a 63 year old Sudanese woman with a history of repeated attacks of right loin pain in whom magnetic resonance urography (MRU) showed multiple filling defects in the right ureter. These were initially thought to be malignant urothelial lesions. Ureteroscopy revealed cystic smooth walled masses which discharged tiny turbid fluid on biopsy. An intraoperative diagnosis of ureteritis cystica was confirmed. The patient was managed conservatively.     

腺性肾盂炎,腺性输尿管炎,腺性膀胱炎和腺性尿道炎的病理学特征

本文对腺性肾盂炎，腺性输尿管炎，腺性尿道炎各１例，及腺性膀胱炎２０例的临床，病理，组织化学和免疫组织化学特征进行了综合分析，探讨了这类泌尿道增生和化生性病变的发病机理，临床处理原则以及与腺癌，腺样分化移行上皮癌，前列腺增生，尿道肉阜和尿道旁腺腺瘤的鉴别诊断要点。     

非特异性输尿管炎16例诊治分析

目的提高非特异性输尿管炎诊治水平.方法对16例非特异性输尿管炎的临床资料进行回顾分析.结果7例行病变输尿管切除及输尿管成形术;9例行输尿管镜检查、活检,其中5例置入双J管、同时做输尿管镜气囊扩张治疗1例,另4例行输尿管镜电灼术.术后随访15例,随访1～12 a,肾积水消失5例,减轻9例,无变化1例,未发现复发及癌变.结论对可疑非特异性输尿管炎患者应行病理检查,切忌盲目行输尿管切除术.     

Hydronephrosis with ureteritis developed in C57BL/6N mice carrying the congenic region derived from MRL/MpJ-type chromosome 11

Inbred MRL/MpJ mice show several unique phenotypes in tissue regeneration processes and the urogenital and immune systems. Clarifying the genetic and molecular bases of these phenotypes requires the analysis of their genetic susceptibility locus. Herein, hydronephrosis development was incidentally observed in MRL/MpJ-derived chromosome 11 (D11Mit21-212)-carrying C57BL/6N-based congenic mice, which developed bilateral or unilateral hydronephrosis in both males and females with 23.5% and 12.5% prevalence, respectively. Histopathologically, papillary malformations of the transitional epithelium in the pelvic-ureteric junction seemed to constrict the ureter luminal entrance. Characteristically, eosinophilic crystals were observed in the lumen of diseased ureters. These ureters were surrounded by infiltrating cells mainly composed of numerous CD3^+?T-cells and B220^+?B-cells. Furthermore, several Iba-1^+?macrophages, Gr-1^+?granulocytes, mast cells and chitinase 3-like 3/Ym1 (an important inflammatory lectin)-positive cells were detected. Eosinophils also accumulated to these lesions in diseased ureters. Some B6.MRL-(D11Mit21-D11Mit212) mice had duplicated ureters. We determined?>100 single nucleotide variants between C57BL/6N- and MRL/MpJ-type chromosome 11 congenic regions, which were associated with nonsynonymous substitution, frameshift or stopgain of coding proteins. In conclusion, B6.MRL-(D11Mit21-D11Mit212) mice spontaneously developed hydronephrosis due to obstructive uropathy with inflammation. Thus, this mouse line would be useful for molecular pathological analysis of obstructive uropathy in experimental medicine.     

腺性输尿管炎2例报道并文献复习

个案报道（如需摘要,修改时可予以补充）     

Ureteritis and pyelitis emphysematosa in a neonate

We describe a case of ureteritis and pyelitis emphysematosa in a neonate. The radiographic features were bilateral linear gas shadows of the ureters joining with gas outlining the renal pelves and calyces.     

Surgical management of nonrenal genitourinary manifestations in children with Henoch-Schönlein purpura

Background/Purpose

The aim of this study was to present the current experience and evidence relating to surgical evaluation and management of nonrenal genitourinary presentation in children with Henoch-Schönlein purpura (HSP). Henoch-Schönlein purpura is the most common systemic vasculitis in childhood. Presenting symptoms include a rash, arthralgia, abdominal pain, and, frequently, renal involvement. Genitourinary symptoms are infrequently reported; however, surgical evaluation is often required.

Methods

A MEDLINE literature search of the last 3 decades was conducted using the terms Henoch-Schönlein purpura in combination with acute scrotum or genitourinary, genital, or related symptoms as the keywords. Reference lists of retrieved articles were reviewed for further relevant articles. Case reports were included when no larger case series were found. Articles of foreign language were included if abstracts proved sufficient information.

Results

Genitourinary manifestations are mainly anecdotally reported. Scrotal pain and swelling were the most frequent nonrenal genitourinary symptoms reported in children with HSP, occurring in about 13% of boys evaluated for HSP. No prospective, population-based reports on genitourinary manifestations in HSP were found, thus making estimation of the true incidence difficult.

Conclusions

A wide variety of nonrenal genitourinary pathology may be expected by surgical evaluation of patients with HSP. Most cases are self-limited in nature. Scrotal symptoms are frequent, but testicular torsion is highly unlikely when the diagnosis of HSP is established. Clinical vigilance should be paid to patients with possible obstructive ureteritis, for whom prompt surgical intervention may be indicated.