敦化市雁鸣湖镇淡水鱼虾吸虫囊蚴感染情况调查

[目的]调查分析敦化市雁鸣湖镇境内淡水鱼虾吸虫囊蚴感染情况.[方法]收集当地21种1 810条淡水鱼和315只淡水虾,解剖提取鱼的肌肉和虾的软体组织,压片,显微镜下观察,进行动物试验以确定寄生虫种类.[结果]在当地淡水鱼虾体内未发现有华支睾吸虫囊蚴的感染;而在大川丁鱼、小川丁鱼及麦穗体内发现有横川后殖吸虫囊蚴的感染,其感染率分别为81.7%,16.1%,3.9%.     

分子标记在医学蠕虫遗传多态性研究中的应用

医学蠕虫引起的人兽共患寄生虫病严重危害人类健康。对医学蠕虫进行遗传多态性研究,不仅可以了解其种群的生物学特性和遗传结构,而且有助于揭示它们如何适应寄生环境,从而有助于对寄生虫病流行规律的认识,加深对寄生虫病精准防控的理解。随着分子生物学的发展,DNA条形码、简单序列重复、单核苷酸多态性标记等分子标记已被广泛应用于研究寄生虫个体间及群体间的遗传关系,揭示寄生虫种群的遗传变异、物种的起源进化等。本文对目前常用的三类分子标记在医学蠕虫遗传多态性研究中的应用进行系统综述,以期为相关研究奠定基础。     

汉城海狸吸虫在我国首次被发现

对枕纹绵蛇、红点绵蛇、蝮蛇的汉城海狸吸虫囊蚴感染情况进行了调查．共查４４条，三种蛇的感染率依序分别为７３．３３％，５７．１４％和８３．３３％。给大白鼠、小白鼠经口感染囊蚴各５０个与２０个，成虫回收率分别为ｏ％～３２％和５％～１０％，依据形态学研究结果，该虫被确认为汉城海狸吸虫．     

扁囊与卫氏并殖吸虫成虫全虫蛋白等电点聚焦和盘状电泳的比较

应用盘状电泳和等电点聚焦电泳的方法对扁囊并殖吸虫和卫氏并殖吸虫成虫的全虫蛋白进行了比较观察,结果表明这两种成虫蛋白质区带模式无明显差异。     

Pharmacotherapy of helminth infection

Background: In the first decade of the 21st century, worm infections are still very common, especially – but not exclusively – in the developing world. Objective: To review the current pharmacotherapy of the major trematode, cestode and nematode infections of humans. Methods: A systematic search of the Cochrane Databank of Controlled Trials and PubMed with MeSH terms (anthelmint^* or treatment or therapy) and (cestoda or trematoda or nematoda or specific helminth species or specific medication). Further references were obtained from article biobliographies. Results: Three hundred and twenty-six publications were selected for further review. Conclusion: Albendazole, praziquantel and ivermectin are the most important anthelmintics available, easy to use and active against most helminths. Diethylcarbamazine is used in loasis and lymphatic filariasis. Doxycycline can eliminate endosymbiotic bacteria of certain filariae, but its place in therapy needs to be further defined. In the treatment of cystic hydatid disease, a better, non-caustic protoscolicidal drug would diminish the complication rate of current puncture–aspiration–injection–reaspiration treatment. The reliance on so few drugs creates a dangerous situation for development of resistance. Triclabendazole is a welcome addition for fascioliasis. Tribendimidine, artemisinine derivatives and nitazoxanide are promising products, but their therapeutic place needs to be further defined.