Laparoscopic salpingotomy for tubal pregnancy: comparison of linear salpingotomy with and without suturing

BACKGROUND: The study was carried out to clarify the incidence of post-operative tubal adhesions, patency rate and pregnancy outcome after laparoscopic salpingotomy with and without suturing for tubal pregnancy. METHODS: From May 1996 to December 2002, a total of 97 cases of tubal pregnancy were treated in our centre by laparoscopic conservative surgery. The successful salpingotomy cases were randomly assigned to undergo salpingotomy without suturing (group I; n = 43) or with suturing (group II; n = 32). We compared these patients and assessed their surgical and pregnancy outcome by second look laparoscopy (SLL) 3 months after the first operation. RESULTS: Seventy-five cases (77%) were treated successfully by salpingotomy at initial laparoscopic surgery, and the remaining 22 cases were unsuccessful because of bleeding or complete tubal damage. Pelvic findings were assessed at SLL in 21 of 43 cases (49%) in group I and 17 of 32 (53%) in group II. There were no significant differences in gestational age, ectopic site, tubal diameter, tubal condition, intraperitoneal haemorrhage and pre-operative HCG levels between the two groups. Only the operation time was longer in group II than in group I (91 +/- 15 versus 69 +/- 15 min, P < 0.05). The tubal patency rate of the treated side was 90% (19/21) in group I and 94% (16/17) in group II. Also the peritubal adhesions were observed in 33% (7/21) in group I and 29% (5/17) in group II, and were mostly comprised of filmy adhesions. A tubal fistula occurred in two cases in each group. Pregnancy rate was 79% (15/19) in group I and 92% (12/13) in group II, and this did not reveal any significant difference of cumulative pregnancy rate between the groups. CONCLUSION: We recommend laparoscopic linear salpingotomy as a useful method in the management of cases with tubal pregnancy who desire future pregnancy. This preliminary study emphasizes that the procedure involving suturing has no additional benefit over the non-suturing technique during salpingotomy.     

Pregnancy: Determinants of reproductive prognosis after ectopic pregnancy

The reproductive prognosis of 115 women desiring pregnancy whounderwent surgery for ectopic pregnancy between 1985 and 1990at the Clinica Luigi Mangiagalli, was analysed after a medianfollow-up period of 26 months (range 2–83). Probabilityof reproductive events was assessed by a product-limit model.Women who underwent surgery for ectopic pregnancy had a 54%probability of becoming pregnant (cumulative pregnancy rate,CPR) and a 36% probability of giving birth to a child (cumulativelivebirth rate, CLB) during the 3 years after surgery. Thesepercentages dropped with history of previous ectopic pregnancy(respectively 33%, P = 0.07, and 7%, P < 0.05). Increasingage at surgery and presence of adhesions in the contra-lateraltube seemed to be associated with poor reproductive prognosis(CPR = 40% and CLB = 12% for women aged 35 years and CPR = 37%and CLB = 20% in women with adhesions in the contra-lateraltube), but these findings were not statistically significant.No association emerged between fertility and parity or typeof surgery. The recurrence rate of ectopic pregnancy was 20%.No significant association emerged between recurrence of ectopicpregnancy and age, history of previous pregnancy, history ofprevious ectopic pregnancy, non-intact contra-lateral tube andsalpingotomy.     

Tubal pregnancy after clomiphene treatment: are you sure is not bilateral?

The estimated prevalence of ectopic pregnancy (EP) is 1–2% worldwide. Bilateral tubal pregnancies represent the rarest form of heterotopic pregnancy, and spontaneously conceived are extremely unusual, as many cases are derived from assisted reproductive techniques. We describe a case of bilateral tubal pregnancy after clomiphene therapy and sexual intercourse in which the second EP was not contemporarily revealed.     

腹腔镜下输卵管线形切开术治疗输卵管妊娠的临床分析及手术技巧总结

目的总结腹腔镜下输卵管线形切开术治疗输卵管妊娠的各种手术技巧。方法回顾分析2008年1月~2011年1月间的56例行腹腔镜下输卵管线形切开术治疗输卵管妊娠的手术情况,观察平均住院日、手术时间、术中出血、术后再次出血、血绒毛膜促性腺激素(HCG)值下降、持续性异位妊娠、术后输卵管通液等情况。结果 56例手术均成功完成,无1例中转开腹和持续性异位妊娠。平均住院日4.3±0.7日,手术时间38.6±8.1min,术中出血35.3±8.6ml,术后引流量(24h)94.6±116.0ml,平均HCG降至正常时间10.8±2.3天,术后2个经期后输卵管通畅率82.1%。结论腹腔镜下线形切开术治疗输卵管妊娠准确有效,并更加微创。     

腹腔镜治疗输卵管妊娠对再次妊娠的影响

目的　研究腹腔镜下行输卵管开窗手术 (简称开窗术 )保留输卵管治疗输卵管妊娠的价值。　方法　对比分析 1994年至 2 0 0 1年腹腔镜下开窗术 2 82例和输卵管切除术 (简称切除术 ) 2 6 0例患者的输卵管通畅度、宫内妊娠、重复异位妊娠和持续性异位妊娠情况。　结果　开窗术组及切除术组的宫内妊娠率分别为 6 1.8% (131/ 2 12 )和 4 0 .5 % (81/ 2 0 0 ) ,差异有显著性 (P<0 .0 1) ;开窗术组术后持续异位妊娠率及重复异位妊娠率分别为 3.3% (7/ 2 12 ) ,14 .6 % (31/ 2 12 )均高于切除组 0 ,7.5 % (15 / 2 0 0 ) ,差异有显著性 (P<0 .0 1,P<0 .0 5 )。　结论　腹腔镜下开窗术后输卵管通畅率及宫内妊娠率高 ,但其持续性异位妊娠及重复性异位妊娠率亦增加。     

垂体后叶素在腹腔镜保守治疗输卵管妊娠中的应用

目的:探讨两点注射垂体后叶素对行腹腔镜输卵管切开术患者术后输卵管通畅度的影响。方法:选择腹腔镜诊断输卵管妊娠且要求进行输卵管切开术的患者66例,按是否使用垂体后叶素分为2组:A组35例,在术中于患侧宫角及输卵管系膜两点注射垂体后叶素进行预处理后再进行输卵管切开术;B组31例,不做预处理。对2组患者的临床资料进行回顾性分析。结果:A组局部手术时间显著短于B组(P<0.01);出血量显著少于B组(P<0.01);2组术后输卵管患侧通畅率A组显著高于B组(P<0.05)。结论:对有生育要求的女性,推荐局部注射垂体后叶素的腹腔镜输卵管切开术。     

联合应用垂体后叶素与肾上腺素对腹腔镜下输卵管妊娠开窗取胚术的价值

目的 探讨不同预处理方法运用于腹腔镜下输卵管妊娠开窗取胚术的安全性及可行性.方法 回顾性病例对照分析2014年10月-2018年10月120例在该院行腹腔镜下输卵管妊娠开窗取胚术的未破裂输卵管妊娠患者的临床资料,根据是否联合应用肾上腺素,将患者分为对照组(n=58)和观察组(n=62例).对照组在子宫角部偏后方与卵巢固...     

腹腔镜手术与开腹手术治疗未破裂型输卵管妊娠临床对比分析

目的 :探讨腹腔镜保守性手术治疗未破裂型输卵管妊娠的临床价值。方法 :对我院确诊为未破裂型输卵管妊娠 92例分组行保守性腹腔镜手术组 4 5例和开腹手术组 4 7例 ,术后随访输卵管的再通和再孕情况 ,并进行对比性分析。结果 :两组病例术中出血量、术后体温、血 βhCG恢复正常时间无显著差异 (P >0 .0 5 ) ;疼痛情况、胃肠功能恢复时间 (以肛门排气时间为准 )、住院时间 ,腹腔镜手术组均低于开腹手术组 (P <0 .0 5 )。腹腔镜手术组和开腹手术组输卵管再通率分别是 84 .4 %、6 1 .7% (P <0 .0 5 ) ;再孕率分别是 5 6 .7%、39.3% (P >0 .0 5 )。结论 :腹腔镜保守性手术是治疗未破裂型输卵管妊娠理想的手术方式 ,值得推广。     

输卵管妊娠诊治过程中应该重视的问题

输卵管妊娠因为常见而缺乏详细深入的临床研究。它看似诊断简单、处理起来也容易，但是一旦被忽视，会导致严重后果，甚至死亡。随着当今社会环境、人们观念的变化，随着IVF等技术的广泛使用，输卵管妊娠出现了新的情况，我们应该重新重视输卵管妊娠的诊断和治疗。     

腹腔镜下输卵管切开术中垂体后叶素不同使用方法的比较性研究

 [目的] 探讨垂体后叶素两点注射法在腹腔镜下输卵管妊娠切开术中的应用价值。 [方法] 将2006年6月～2007年12月我院妇科未破裂输卵管妊娠患者200例，均行腹腔镜下输卵管切开术，分成三组，其中术中两点注射垂体后叶素组(观察1组)72例、单点注射垂体后叶素组(观察1组)62例和未使用垂体后叶素组（对照组）66例，对照组：66例，即腹腔镜下输卵管切开前不使用垂体后叶素。比较三组的手术时间、术中出血量、术后最高体温、手术并发症等。[结果] 观察1组和观察2组的手术时间、术中出血量均明显少于对照组（P<0.05），观察1组少于观察2组（P<0.05）。观察1组的持续性宫外孕发生率低于对照组（P<0.01），观察2组的持续性宫外孕发生率与观察1组和对照组比较无显著性差异（P>0.05）。3组术后最高体温无明显差异（P>0.05）。使用垂体后叶素的患者无1例副反应发生。 [结论] 在腹腔镜下输卵管切开术中应用垂体后叶素注射，能减少术中出血，缩短手术时间并减少持续性宫外孕等并发症的发生，在患侧宫角及输卵管系膜两点注射法优于输卵管系膜单点注射法，两种方法都安全可靠。