芪月降脂片制剂处方的优化

[目的 ]优化芪月降脂片的制剂处方 .[方法 ]采用正交设计和多指标综合评分法对已筛选出的药剂辅料进行处方优化 .[结果 ]最佳制剂处方为糖粉 50 g ,辅料X 50g ,微晶纤维素 75g .[结论 ]该处方合理 ,成型性好     

刺五加对~(60)Co-γ射线照射后小鼠胸腺效应的实验研究

采用180只成年小白鼠(雌雄各半),其中168只经一次总剂量为4Gy的~(60)Co—γ射线照射,造成造血放射损伤,再从其中随机选出56只膜腔注射刺五加注射液作为实验用药组,其余小白鼠随机分为盐水对照组(56只),空白对照组(56只)及正常对照组(12只)。实验结果显示。实验用药组的胸腺细胞超微结构的恢复比同期对照组快,胸腺组织DNA含量比同期对照组高。因此,我们认为刺五加可促进辐射损伤后小白鼠胸腺细胞结构的恢复。     

川芎挥发油化学成分研究

采取闪蒸气相毛细管色谱法和气相毛细管色谱—质谱法研究了宁夏六盘山区产川芎的挥发油化学成分,色谱分离出50多个峰,质谱鉴定了24个成分,主要是川芎酜内酯(46.37％)、丁基酞内酯(13.87％)、新蛇床内酯(6.98％)和丁烯基酜酯(4.8％)。红外光谱图中有较强的内酯特征吸收峰,为质谱所鉴定的以上主要成分提供了佐证。将闪蒸气相色谱法与蒸气蒸馏提取气相色谱法进行对照,二者的色谱图基本相符,前者是分析天然产物挥发性成分更加简便、迅速的微量方法。     

肺螨类生境研究

本文叙述了肺螨类的孳生环境及其不同生境里肺螨的种群分布,并对分离出的28种螨的生境和肺螨病患者的工作环境进行了对比分析,认为螨在肺螨病患者工作环境中的分布和肺螨的生境基本上相符合,因此证实了患者的病原体是直接来源于工作环境。     

TH胶胃冠状静脉栓塞术治疗门脉高压症

11例TH胶胃冠状静脉栓塞术临床治疗结果表明:(1)11例中的4例急性上消化道大出血患者均在12h左右出血基本停止,随访近一年未再发生出血现象。(2)10例半年后复查肝功能均有不同程度改善。(3)一年后复查食道钡餐透视X线平片发现8例患者食道静脉曲张有不同程度减轻。(4)11例中1例因术中急性肝功能衰竭死亡。因此我们认为此术式操作简便,手术创伤小、较易推广,是治疗门脉高压症合并食管胃底静脉曲张出血的一种有效方法。     

Distribution of input synapses from processes exhibiting GABA- or glutamate-like immunoreactivity onto terminals of prosternal filiform afferents in the locust

The locust prosternum carries a population of long filiform hairs that are very sensitive to air currents. The sensory afferent neurons that innervate the hairs make strong monosynaptic connections with an identified intersegmental interneuron (A4I1) which is known to contact motor neurons that supply muscles controlling wing angle during flight. In order discover how the synapse between the afferents and interneuron A4I1 might be modulated, the afferents were labelled intracellularly by backfilling with horseradish peroxidase to reveal their central terminals which lie in the prothoracic ganglion. A postembedding immunogold method was used to make a quantitative assessment of the prevalence of immunoreactivity for GABA and glutamate in processes presynaptic to the afferent terminals. In one afferent neuron, where 77 synapses were examined, 40 (52%) of the presynaptic processes were immunoreactive for GABA. When adjacent sections through the same terminal branches were labelled with the two antibodies, it was demonstrated that GABA- and glutamate-like immunoreactivity was present in different populations of presynaptic processes. A series of 110 ultrathin sections was cut through one set of afferent terminal branches and alternate grids were stained with GABA and glutamate antibodies. From these sections, the terminals were reconstructed and the position of 35 input and 21 output synapses mapped. Of the 35 input synapses, 18 (51%) were immunoreactive for GABA, 14 (40%) were immunoreactive for glutamate and 3 (9%) were unlabelled by either antibody. On these terminals, the different classes of input synapses appeared to be intermingled at random with the output synapses made by the afferent, and no pattern govering synapse distribution could be discerned. © 1994 Wiley-Liss, Inc.     

丙帕锗的制备及分析

目的 探索合成条件，制备体内活性和稳定性好的高聚物丙帕锗．并分析其结构确定目的物的正确性。方法 以GeO2为起始原料，磷酸二氢钠为还原剂,制备3-氧锗丙烯酸低分子量聚合物和高分子量3-氧锗丙烯酸(丙帕锗)，并进行元素、红外光谱、核磁共振和X-射线的分析。结果 高分子量聚合物生成，在320℃以下不分解，终产率为72．9％。结论 所采用的方法可行，合成的产品结构正确。     

针刺配合中药治疗24例小儿高热惊厥临床观察

针药并用，针刺人中、百合、涌泉、合谷，中药内服疏风情热，表里双解，止痉退烧，双管齐下治疗２４例小儿高热惊厥，经治疗均获痊愈。