Marine biodiversity as a source of chemical diversity

Total global biodiversity is estimated at between 3 and 500 × 10⁶ species of prokaryote and eukaryote organisms spread across 70 or more phyla. The marine macrofauna alone are estimated between 0.5 and 30 × 10⁶ species and represents a broader range of taxonomic diversity than that found in the terrestrial environment, which has been the traditional source of natural products. With a typical eukaryote possessing 50,000 genes, the global marine macrofauna are the source of 2.5 × 10¹⁰ to 1.5 × 10¹² primary products and an associated extensive range of secondary products. However, only a few thousand novel compounds from marine organisms have been described. These compounds have proven unique in chemical and pharmacological terms but, as yet, no therapeutic agents have resulted. Given a broader drug discovery strategy, and facilitated by technological advances, it is predicted that the characterisation of marine chemical diversity will be accelerated. Strategies for drug discovery from the virtually untapped chemical diversity of marine organisms are discussed. © 1994 Wiley-Less, Inc.     

角膜缝线的细菌学试验研究

对常用的4种角膜缝线进行细菌的吸附试验和虹吸试验。结装发现3-0黑丝线吸附细菌最多,10-0尼龙线吸附细菌最少。3-0和5-0黑丝线对细菌虹吸试验阳性,9-0和10-0尼龙线虹吸试验阴性。试验证明,10-0尼龙线是角膜手术较理想的缝线。     

平时罕见,特殊情况下发生的几种伤病

一些损伤和疾病平时罕见，特殊情况下可以发生，造成严重危害。特殊情况主要包括严重事故、灾害、战争、恐怖主义活动以及特殊环境与特殊作业的危害等。本阐述了现代战争中发生的贫铀武器伤害、燃料空气炸弹伤害、微波武器伤害和战时精神疾病；可能源于恐怖主义活动的炭疽、天花；严重事故性伤害中的核事故、化学事故和煤矿事故伤害；严重灾害中的地震、海难(海战)落海伤害。中介绍了这些伤病的发生情况、伤害特点与医学救治。     

从临床标本分离出510株病原菌的初步报告

报告１９９４年我院临床标本检出的常见菌及其对抗生素的敏感性变化。结果表明，革兰氏阴性杆菌占检出菌的第一位６３．７２％，革 兰氏阳性菌居第二位２９．４１％。在革兰氏阴性杆菌中铜绿假单胞菌居首位，并占革兰氏阴性杆菌的２９．２３％；大肠艾希氏菌占第二位２２．７７％，不动杆菌占第三位１２．３０％。在革兰氏阳性球菌中，凝固酶阴性葡萄球菌居检出菌的第一位，并占革兰氏阳性球菌的３７．３３％；金黄色葡萄球菌占第二     

应用荧光免疫法检测生殖道沙眼衣原体及加德纳细菌

应用标记荧光素的抗沙眼衣原体(Chlamydia trachomatis,Ct)和抗阴道加德纳细菌(Gardnerella Vaginalis,GV)单克隆抗体,直接免疫荧光法(DFA)检测66例妇女生殖道标本。结果显示:Ct感染率为12.12％,GV感染率为19.70％。在妇科门诊患者Ct和GV感染率较高,应引起高度重视,18～40岁妇女是重点防治对象。     

The influence of 3 types of subtotal gastrectomy on intragastric bacterial overgrowth in 43 cases

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Acute nonlymphatic leukemia among deck officers on coastal tankers: a report of two cases

Deck officers on coastal tankers may be exposed to high concentrations of cargo vapors during loading and tank-cleaning operations. Two cases of acute nonlymphatic leukemia are described. Both men had worked as chief officers on coastal tankers transporting benzene and other petroleum products.     

月桂氮(艹卓)酮的抑菌作用观察

月桂氮Ｚｈｕｏ酮（氮酮）作为一种高效透皮吸收促进剂，已广泛应用于医药化妆品等领域，本实验中发现，氮酮在２０μｇ／ｍｌ浓度下，对Ｇ＾＋细菌及芽孢具有显著的抑制作用。     

白内障囊外摘除术房水细菌培养的临床观察

对36例白内障囊外摘除术抽吸前房水进行细菌培养，其中16例细菌培养阳性，大多为表皮葡萄球菌，菌落的形态很小，绝大多数为10－30个／ml，无1例发生眼内炎。这提示白内障术后前房可清除少量的细菌而不发生服内感染。     

Viruses Infecting Marine Brown Algae

Viruses infecting algal hosts possess large double-stranded DNA as genomes. We have recently identified a family of viruses specific for filamentous brown algae. In contrast to the better known Chlorella viruses with their lytic infection cycle, marine brown algal viruses latently occur in their host cells and are induced to multiply in response to a variety of external stimuli such as change in light and temperature. Here, I summarize the known properties of this family of viruses and discuss their taxonomic classification.