络石藤中的三萜类化合物

目的对络石藤中的三萜类化合物进行分离鉴定。方法采用硅胶、反相硅胶、Sephadex LH-20等柱色谱方法进行分离,NM R等波谱学方法进行结构鉴定。结果从络石藤中分离鉴定8个三萜类化合物:络石苷F(tra-che losperos ide F,Ⅰ)、络石苷B-1(trache losperos ide B-1,Ⅱ)、络石苷D-1(trache losperos ide D-1,Ⅲ)、络石苷E-1(trache losperos ide E-1,Ⅳ)、3-βO-D-g lucopyranos ide qu inov ic ac id(Ⅴ)、3β-O--βD-g lucopyrano isde qu inov ic ac id27-O--βD-g lucopyranosy l ester(Ⅵ)、3β-O--βD-g lucopyranos ide c incho lic ac id 27-O--βD-g lucopyranosy l ester(Ⅶ)、络石苷元B(trache losperogen in B,Ⅷ)。结论Ⅰ为新化合物,其余均为首次从该植物中分离得到。     

Clinical effectiveness of an autopolymerized fissure sealant after 2 years

The clinical effectiveness of Delton fissure sealant was studied in 205 children, ages 6--10 years (mean age 71/2). 993 children in grades 1, 2, 3 and 4 were screened and subjects were selected if there was evidence of previous dental caries in the mouth, and a pair of contralateral maxillary or mandibular first permanent molar teeth were free of caries. Two pedodontists independently examined the children in a mobile van equipped with two operatories, and each applied sealants to approximately half of the subjects. After 11 months, in 186 subjects there were 10 sealants partially lost, five experimental teeth carious or filled and 53 control teeth carious or filled. After 24 months, in 175 subjects there were four sealants completely lost, 12 sealants partially lost, 11 experimental teeth carious or filled and 89 control teeth carious or filled. Consequently, sealant retention was 92% after 11 months and 85% after 24 months. Percent effectiveness in caries reduction was 90% after 11 months and 88% after 2 years.     

A 3-year study among Yugoslavian schoolchildren on caries reduction after topical application of 4% NaF-PO4

The purpose of this study was to test the caries-inhibiting effect of 4 %NaF in 0.1M H₃PO₄, pH 4.6 after application once or twice a year. Four hundred and ninety-seven children, 10–12 years old, with totally repaired teeth, were randomly divided into three groups, which were treated as follows: Group 1: control, Group 2: fluoride topical application once a year, Group 3: fluoride topical application twice a year at 6-month intervals. The differences among groups were analyzed on the basis of caries increment of teeth and of caries increment of surfaces. The analysis was made for all teeth, for teeth present initially and for teeth erupted during the study. The 3-year study showed that topical application of NaF-POj solution causes a significant caries inhibition in children at that age. It can be stated that the caries reduction expressed in DFT as well in DFS for all teeth was higher in Group 3 (about 30%) than in Group 2 (about 20%). This difference was especially marked for newly erupted teeth (34.4 % against 8.3 %).     

Relation between social drug use/abuse and dental disease in California, U.S.A.

ABSTRACT This study has explored the social drug use/abuse patterns associated with dental disease. Seventy-seven subjects from the Berkeley Free Clinic were given questionnaires on their drug-use habits and then were examined for both DMF-T and OHI-S scores. Ninety-seven percent of the subjects indicated that they used one or more of the eight drugs being surveyed. The mean DMF-T of the subjects was 13.2 and the OHI-S was 2.61. The study indicated that persons who used barbiturates, miscellaneous hallucinogens and heroin have poorer oral hygiene than those in other categories. An unexpected finding was that subjects who used four or five of the surveyed drugs had lower DMF-T and OHI-S scores than those who used a lesser or a greater number of these drugs. The significance of these findings for an individual's oral health is not yet clear, but it is interesting that the oral hygiene index and DMF-T index did not increase with the increasing number of drugs used, although the specific use of barbiturates, miscellaneous hallucinogens and heroin were related to higher OHI-S scores. The lower OHI and DMF scores probably can be explained by the frequency of toothbrushing. Ninety-five percent of the 4–5 drug-use group brushed one or more times per day.     

榼藤藤茎醋酸乙酯部位化学成分的研究

目的 对榼藤Entada phaseoloide藤茎醋酸乙酯部位的化学成分进行研究。方法 综合运用硅胶、反相硅胶RP C18、Sephadex LH-20等色谱法进行分离,NMR、MS等波谱学方法进行结构鉴定。结果 从榼藤藤茎甲醇提取物的醋酸乙酯萃取部位中分离得到了11个化合物,通过波谱分析鉴定为表没食子儿茶素没食子酸酯（1）、表儿茶素没食子酸酯（2）、落新妇苷（3）、木犀草素（4）、（?）-表儿茶素（5）、甘草苷（6）、β-香树脂醇（7）和日耳曼醇（8）的混合物、没食子酸（9）、β-谷甾醇（10）、胡萝卜苷（11）。结论 所有化合物均为首次从榼藤中分离得到,其中化合物1～9在榼藤子属植物首次报道。     

络石藤中的三萜类化合物

目的对络石藤中的三萜类化合物进行分离鉴定。方法采用硅胶、反相硅胶、Sephadex LH-20等柱色谱方法进行分离,NM R等波谱学方法进行结构鉴定。结果从络石藤中分离鉴定8个三萜类化合物:络石苷F(tra-che losperos ide F,Ⅰ)、络石苷B-1(trache losperos ide B-1,Ⅱ)、络石苷D-1(trache losperos ide D-1,Ⅲ)、络石苷E-1(trache losperos ide E-1,Ⅳ)、3-βO-D-g lucopyranos ide qu inov ic ac id(Ⅴ)、3β-O--βD-g lucopyrano isde qu inov ic ac id27-O--βD-g lucopyranosy l ester(Ⅵ)、3β-O--βD-g lucopyranos ide c incho lic ac id 27-O--βD-g lucopyranosy l ester(Ⅶ)、络石苷元B(trache losperogen in B,Ⅷ)。结论Ⅰ为新化合物,其余均为首次从该植物中分离得到。     

小学生龋患儿头发6种元素含量变化

用原子吸收光谱法检测汉中市１７４例小学生龋患儿及１５９名对照组小学生头发微量元素Ｃｕ、Ｚｎ、Ｆｅ、Ｍｎ及常量元素Ｃａ、Ｍｇ的含量。结果表明龋患组发Ｃａ含量明显低于对照组（Ｐ〈０．０１）;女生龋患组发Ｚｎ、Ｆｅ、Ｍｇ含量低于女生对照组同指（Ｐ〈０．０５）;常态下女生发Ｃａ、Ｍｇ、Ｚｎ、Ｆｅ含量明显高于男生同指标（Ｐ〈０．００１或Ｐ〈０．０１）;发Ｃａ、Ｍｇ、Ｚｎ、Ｍｎ５种元素之间有不同程度的相关性。     

镧、钙、氟对釉质脱矿影响的比较

目的：用化学致龋法对比镧、钙、氟对釉质脱矿的影响。方法：１５０个离体前磨牙分成６组,用酸性凝胶化学致龋,偏光显微镜观察龋形态及深度。结果：各实验组龋深度均浅于对照组,镧处理组龋深度浅于钙、氟及镧氟、氟镧先后处理组。结论：推测镧可从改善釉质结构及增加釉质外环境中钙饱和度两方面增强釉质的抗酸能力。