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1.
Mariko Morimoto 《Health marketing quarterly》2020,37(2):108-123
AbstractThis research explores how the level of consumers’ need for cognition (NFC) is associated with celebrity endorser credibility and examines its effects on advertising-related attitudes. A 3 (endorser types: actor/actress, athlete, TV personality/talent) × 2 (endorser’s gender) factorial experiment with 435 Japanese consumers was conducted. Concerning Japanese OTC drug advertising, lower NFC individuals perceived celebrity endorsers as more credible in comparison to higher NFC individuals. The main effects of NFC and endorser type on endorser credibility existed; however, no interaction between the two variables was found. The endorser type had an influence on attitudes toward ads and the advertised brand. 相似文献
2.
The suicide substrate reaction is a model for certain enzyme-inhibitingdrugs. This reaction system is examined assuming that the substratediffuses freely while the enzyme remains fixed. Two sets ofinitial and boundary conditions are examined: one modellingan instantaneous point source, akin to an injection of substrate,the other, a continuous point source, akin to a continuing influx,or intravenous drip, of substrate. The quasi-steady-state assumptionis applied to obtain analytical solutions for a limited parameterspace. Finally, further applications of numerical and analyticalexperimentation on pharmaceutical mechanisms are described. 相似文献
3.
从机械和电路两方面分析了 KLHZ-001型后装机出源阻力大的原因 ,并分别阐述了维修办法. 相似文献
4.
以23例肾功能不全与20例肾功正常患者的唾液尿素氮、钠、钾、舌面pH值和血液的相应生化检查作对照。结果唾液尿素氮、钾与血尿素氮、钾成正相关性。证实了中医“津血同源”“肾为唾”的理论。 相似文献
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目的观察一例大剂量全身极不均匀照射急性放射损伤患者数处局部病理改变。方法病理常规切片染色,光镜检查。结果吸收剂量右下肢为3738Gy,左手掌为830Gy,于照射后第8天行右下肢、左前臂截肢术。右手、左膝照射剂量相对较小但难以准确估计,红斑、水肿、水疱、溃疡出现相对较晚,于第55天行右手指、左膝清创植皮术。镜下:右小腿局部皮肤和皮肤附属器官、皮下组织和骨胳肌广泛地坏死和弥漫性出血,但真皮中的立毛肌尚存;左手指、手掌皮肤表皮细胞空泡变性、坏死,并形成大小不一的囊泡,致使表皮与真皮分离,真皮弥漫性出血、中性粒细胞浸润,汗腺上皮细胞变性、坏死,皮下组织内弥漫性出血,少数脂肪细胞坏死。胫骨、腓骨上端和股骨、桡骨、尺骨下端处骨髓腔内造血组织各系细胞均消失。左膝、右手拇指、食指、中指皮肤示急性放射性溃疡。结论大剂量照射导致的急性放射损伤造成大面积、深达肌肉的软组织坏死及骨髓造血细胞消失。 相似文献
7.
中国饮用水源水中藻类卫生标准的研究 总被引:17,自引:0,他引:17
为制定饮用水源中藻类限值 ,结合国内外文献调查研究毒理学试验和现场生态学调查资料 ,根据世界卫生组织 (WHO)和卫生部推荐的饮用水中微囊藻毒素MC -LR的限值、藻类生物量和MC -LR浓度关系以及毒理学实验所得到的藻类的无作用浓度而制定饮用水源中藻类限值。结果显示 ,推荐饮用水源中藻类三级限值分别为 :安全限值 :1.0× 10 4个 升 ;警戒限值 :2 .1× 10 5个 升 ;危险限值 :1.2× 10 6 个 升。提示饮用水源中藻类限值在日常工作中有显著意义和可行性 相似文献
8.
A. L. Marchese PhD J. M. Maggiano A. H. Friedman 《Documenta ophthalmologica. Advances in ophthalmology》1992,79(2):117-124
We recorded the electro-oculogram from 27 normal subjects by means of green and near-ultraviolet (UVA) stimulation. After a 40-minute dark-adaptation period, baseline responses were recorded. In response to the green stimulus, the electro-oculogram increased from this level by an average (± standard error of the mean) of 49.5% ±4.0%. Although the predicted scotopic effectiveness of the ultraviolet stimulus was more than 3 log units below that of the green stimulus, the near-ultraviolet-induced electro-oculogram increased to an average of 21.9% ±3.0% above baseline. This response cannot be due to lens fluorescence to the near-ultraviolet stimulus, since two aphakic subjects had electro-oculographic responses of 32% and 76% above baseline to near-ultraviolet stimuli. Neither the green nor the ultraviolet electro-oculogram changed significantly with age. These large responses to near-ultraviolet stimulation demonstrate the need for standardizing light sources for electro-oculographic testing because the degree of near-ultraviolet irradiance varies considerably according to their design characteristics. 相似文献
9.
L.E. Oostenbrug I.M. Nolte E. Oosterom G. van der Steege G.J. te Meerman H.M. van Dullemen J.P.H. Drenth D.J. de Jong K. van der Linde P.L.M. Jansen J.H. Kleibeuker 《Digestive and liver disease》2006,38(11):834-845
BACKGROUND: Three major polymorphisms of the Caspase-Activation Recruitment Domain containing protein 15 gene have been described to be associated with Crohn's disease. Genotype-phenotype studies reported in literature provide conflicting data on disease localisation and behaviour. We investigated the relation of Caspase-Activation Recruitment Domain containing protein 15 with inflammatory bowel disease and Crohn's disease phenotypic characteristics in a large Dutch cohort and performed a pooled analysis on inflammatory bowel disease patients and Crohn's disease phenotypic characteristics reported in association studies. METHODS: We genotyped 781 cases and 315 controls for the R702W, G908R and 1007fsinsC variants and for six microsatellite markers in and close to Caspase-Activation Recruitment Domain containing protein 15. In the pooled analysis data of 7201 inflammatory bowel disease patients and 3720 controls from 20 studies were included. RESULTS: Association was found for Crohn's disease with R702W and 1007fsinsC, including several disease characteristics, and not for ulcerative colitis. In the pooled analysis all three common Caspase-Activation Recruitment Domain containing protein 15 variants showed strong association with Crohn's disease (p<0.00001; odds ratio varying from 3.0 for single heterozygotes to 14.7 for compound heterozygotes) and not with ulcerative colitis. Phenotype analysis showed association with small bowel involvement, stricturing and penetrating disease. CONCLUSION: Caspase-Activation Recruitment Domain containing protein 15 is associated with Crohn's disease and not with ulcerative colitis. All three common Crohn's disease-associated variants are associated with small bowel involvement, the G908R and 1007fsinsC alleles also being associated with a complicated disease course. 相似文献
10.
R. Kristeva-Feige H. Walter B. Lütkenhöner S. Hampson B. Ross U. Knorr H. Steinmetz D. Cheyne 《The European journal of neuroscience》1994,6(4):632-639
Movement-related neuromagnetic fields from eight healthy human subjects were investigated in a Bereitschaftspotential paradigm. The three conditions studied were right-sided mouth, index finger and foot movement. The neuromagnetic field patterns corresponding to the motor field and the movement-evoked field I were analysed using a moving dipole model. For both components a somatotopic organization was found: the estimated dipole locations for the mouth were more lateral and those for the foot more medial than the estimated dipole positions for the index finger movement. With regard to possible clinical applications, e.g. non-invasive mapping of the sensorimotor cortex and studies of plasticity of the motor function, the present results suggest that the investigation of movement-evoked field I for the index finger condition is most likely to yield further results. 相似文献