低管电流联合 SAFIRE 重建在颈部肿大淋巴结的双能量 CT 扫描中的应用

目的：探讨低管电流联合 SAFIRE 重建的双能量 CT 扫描在颈部肿大淋巴结诊断中的应用。方法经病理证实的50例颈部肿大淋巴结的患者,进行常规 CT 平扫及双能量动脉期扫描,将其随机分为2组,即实验组和对照组,每组25例。实验组管电压分别为100 kV 和 Sn140 kV,管电流分别为117 mAs 和109 mAs,图像重建采用 SAFIRE 迭代重建技术,值选3;对照组管电压分别为100 kV 和 Sn140 kV,管电流分别为189 mAs 和165 mAs,1.0 cm,图像重建算法采用滤波反投影(FBP)技术,其余参数均相同。由2名有经验的医师对2组图像质量进行双盲法评分,利用 Kappa 检验比较观察者间评分的一致性;采用独立样本 t 检验比较2组患者的图像质量及有效辐射剂量。结果2组患者平均 CT 值的比较无统计学差异(P >0.05);2组噪声及信噪比(SNR)的比较有统计学差异(t 分别为4.705、4.403,P 分别为0.0008、0.0007);2组对比噪声比(CNR)无统计学差异(P >0.05);2组图像主观评分一致性较好(Kappa=0.720)且无统计学差异(P >0.05);实验组容积 CT 剂量指数(CTDIvol)为(10.801±0.594)mGy,剂量长度乘积(DLP)为(270.317±5.439)mGy·cm,有效辐射剂量(ED)为(1.594±0.031)mSv,对照组 CTDIvol 为(18.870±0.356)mGy, DLP 为(464.560±1.577)mGy·cm,ED 为(2.741±0.009)mSv,实验组 ED 较对照组降低约41.8%,且2组差异均有统计学意义(P <0.05)。结论在颈部肿大淋巴结的双能量扫描中,低管电流联合 SAFIRE 迭代重建能够在保证图像质量的同时,降低受检者所接受的辐射剂量。     

正弦图确认迭代重建技术在胸部低剂量CT扫描中的应用价值

目的 探讨正弦图确认迭代重建（SAFIRE）技术在胸部低剂量CT扫描中的应用价值。方法 随机选取亳州市人民医院2014年6月至2014年12月有前后2次胸部CT扫描记录的30例患者影像学资料,2次扫描分别为传统的滤波反投影重建（FBP）及SAFIRE技术,SAFIRE强度为Strenth3;统计比较每位患者2次扫描图像的CT值、噪声（SD）、信噪比（SNR）及有效辐射剂量（ED）。结果 两组上肺部（胸大肌）、中肺部（升主动脉根部）及下肺部（椎旁软组织）的CT值分别为：FBP组为（51.19±6.22）HU、（42.87±7.37）HU、（45.84±8.37）HU;SAFIRE组为（53.91±12.89）HU、（42.55±8.20）HU、（44.43±15.47）HU;两组平扫SD分别为：FBP组为（8.65±2.07）HU、（9.19±1.69）HU、（13.27±3.05）HU,SAFIRE组为（18.41±18.00）HU、（19.20±15.71）HU、（29.24±30.09）HU;两组之间差异均无统计学意义（P>0.05）;两组的SNR分别为：FBP组为6.31±1.87、4.82±1.06、3.73±1.36,SAFIRE组为4.39±2.20、3.03±1.33、2.45±1.43,两组之间差异有统计学意义（P<0.05）;两组的ED值：FBP组为（2.84±0.88）mSv,SAFIRE组为（1.27±0.64）mSv,两组之间差异有统计学意义（P<0.05）;两组图像主观评分差异无统计学意义（P>0.05）。结论 与传统FBP重建技术相比,SAFIRE重建技术能够在保证图像质量不影响诊断的同时,有效地降低CT辐射剂量,从而保证患者的安全。     

探讨SAFIRE技术在降低胸部扫描剂量中的应用价值

目的：探讨正弦图确定迭代重建（SAFIRE）技术在降低胸部扫描剂量中的应用价值。方法选取2013年11月于我院作胸部CT检查的80例患者,将患者随机分成两组（对照组和低剂量组）,每组各40人。对照组采用管电压130 kV和滤波反投影（FBP）重建技术,低剂量组采用管电压80 kV和SAFIRE（Strength 3级）技术。分别测量两组气管分杈层面降主动脉和同层背部肌肉的CT值及其标准差（SD）、信噪比（SNR）、对比噪声比（CNR）;记录两组患者的CT剂量指数（CTDI）、剂量长度乘积（DLP）,并估算有效剂量（ED）。由两名医师对图像质量采用5分制进行评估,并用Kappa检验评价医师评分结果的一致性。结果对照组的CTDI为（6.71±1.06）mGy,DLP为（237.75±45.76） mGy·cm,ED为（3.33±0.64） mSv;低剂量组的CTDI为（2.08±0.28） mGy, DLP为（78.53±11.35） mGy·cm,ED为（1.10±0.16） mSv;两组差异均有统计学意义（P＜0.05）。对照组的SNR为（6.84±1.83）,CNR为（2.25±1.05）;低剂量组的SNR为（6.43±1.32）,CNR为（1.99±1.41）,两组差异均无统计学意义（P＞0.05）且图像质量均能满足临床诊断要求,医师间的评估结果具有较好的一致性（Kappa=0.764）。结论胸部低剂量CT结合SAFIRE技术,可在不影响诊断效果的情况下,显著降低辐射剂量。     

正弦图确认迭代重建技术在胸部低剂量CT扫描中的应用价值

目的 探讨正弦图确认迭代重建(SAFIRE)技术在胸部低剂量CT扫描中的应用价值.方法 随机选取亳州市人民医院2014年6月至2014年12月有前后2次胸部CT扫描记录的30例患者影像学资料,2次扫描分别为传统的滤波反投影重建(FBP)及SAFIRE技术,SAFIRE强度为Strenth3;统计比较每位患者2次扫描图像的CT值、噪声(SD)、信噪比(SNR)及有效辐射剂量(ED).结果 两组上肺部(胸大肌)、中肺部(升主动脉根部)及下肺部(椎旁软组织)的CT值分别为:FBP组为(51.19±6.22)HU、(42.87 ±7.37)HU、(45.84 ±8.37)HU;SAFIRE组为(53.91±12.89)HU、(42.55±8.20) HU、(44.43±15.47) HU;两组平扫SD分别为:FBP组为(8.65±2.07) HU、(9.19 ±1.69)HU、(13.27±3.05) HU,SAFIRE组为(18.41±18.00) HU、(19.20±15.71)HU、(29.24 ±30.09)HU;两组之间差异均无统计学意义(P＞0.05);两组的SNR分别为:FBP组为6.31 ±1.87、4.82±1.06、3.73±1.36,SAFIRE组为4.39±2.20、3.03 ±1.33、2.45±1.43,两组之间差异有统计学意义(P＜0.05);两组的ED值:FBP组为(2.84±0.88) mSv,SAFIRE组为(1.27±0.64) mSv,两组之间差异有统计学意义(P＜0.05);两组图像主观评分差异无统计学意义(P＞0.05).结论 与传统FBP重建技术相比,SAFIRE重建技术能够在保证图像质量不影响诊断的同时,有效地降低CT辐射剂量,从而保证患者的安全.     

Stent evaluation in low-dose coronary CT angiography: Effect of different iterative reconstruction settings

BackgroundDifferent iterative reconstruction (IR) techniques compensate increased noise from lower tube current-time product settings, yet the differences between IR settings remain unclear.ObjectiveAim of this study was to test whether different IR settings have a clinically relevant influence on image quality and on the diagnostic accuracy of low-dose CT angiography in patients with a stent.MethodsForty-two patients with 73 coronary stents were prospectively enrolled. Data were acquired with dual-source CT, and images were reconstructed with standard filtered back projection (FBP) and raw data-based IR with different settings (I3, I4, I5). Quantitative parameters, including CT-attenuation, noise, signal-to-noise ratio, contrast-to-noise ratio, as well as the presence of in-stent stenosis > 50% were determined. All patients had invasive angiography as reference standard.ResultsMean effective dose was 0.32 ± 0.02 mSv. Image noise decreased significantly compared with FBP (I3 = 29%; I4 = 38% and I5 = 45%), whereas signal-to-noise and contrast-to-noise ratios increased significantly (all IR settings P < .01). Subjective image quality was superior with all IR settings (P < .01). FBP sensitivity, specificity, positive predictive value, and negative predictive value were 83%, 71%, 36%, and 96% per stent compared with 100%, 76%, 44%, and 100%, respectively, in IR reconstructions independent of the IR setting applied.ConclusionIn low-dose coronary CT angiography, higher IR settings significantly improved subjective and objective image quality but had no effect on accuracy.     

Feasibility of slice width reduction for spiral cranial computed tomography using iterative image reconstruction

Purpose

To prospectively compare image quality of cranial computed tomography (CCT) examinations with varying slice widths using traditional filtered back projection (FBP) versus sinogram-affirmed iterative image reconstruction (SAFIRE).

Materials and methods

29 consecutive patients (14 men, mean age: 72 ± 17 years) referred for a total of 40 CCT studies were prospectively included. Each CCT raw data set was reconstructed with FBP and SAFIRE at 5 slice widths (1–5 mm; 1 mm increments). Objective image quality was assessed in three predefined regions of the brain (white matter, thalamus, cerebellum) using identical regions of interest (ROIs). Subjective image quality was assessed by 2 experienced radiologists. Objective and subjective image quality parameters were statistically compared between FBP and SAFIRE reconstructions.

Results

SAFIRE reconstructions resulted in mean noise reductions of 43.8% in the white matter, 45.6% in the thalamus and 42.0% in the cerebellum (p < 0.01) compared to FBP on non contrast-enhanced 1 mm slice width images. Corresponding mean noise reductions on 1 mm contrast-enhanced studies were 45.7%, 47.3%, and 45.0% in the white matter, thalamus, and cerebellum, respectively (p < 0.01). There was no significant difference in mean attenuation of any region or slice width between the two reconstruction methods (all p > 0.05). Subjective image quality of IR images was mostly rated higher than that of the FBP images.

Conclusion

Compared to FBP, SAFIRE provides significant reductions in image noise while increasing subjective image in CCT, particularly when thinner slices are used. Therefore, SAFIRE may allow utilization of thinner slices in CCT, potentially reducing partial volume effects and improving diagnostic accuracy.     

SAFIRE重建联合80kV管电压对甲状腺癌CT检查质量及安全性的影响

目的探讨正弦图确定迭代重建(SAFIRE)联合80kV管电压对甲状腺癌CT检查质量及安全性的影响。方法选取我院疑似甲状腺癌患者(均存在甲状腺结节病变)106例,SAFIRE重建联合80kV管电压检查的53例作为试验组,滤波反投影法重建联合120kV管电压的53例作为对照组。对比两组辐射剂量参数指标[有效剂量(ED)、剂量长度乘积(DLP)、容积剂量指数(CTDIvol)]、客观图像质量指标[信噪比(SNR)、对比信噪比(CNR)、CT值]水平、主观图像质量评分,以病理检查结果作为“金标准”,分析应用SAFIRE重建联合80kV管电压进行CT检查诊断甲状腺癌的符合率。结果试验组ED、DLP、CTDIvol均低于对照组(P<0.05);两组图像质量均能满足诊断需要,且两组主观图像质量评分相比,差异无统计学意义(P>0.05);两组SNR、CNR、CT值相比,差异无统计学意义(P>0.05);病理检查作为“金标准”,以SAFIRE重建联合80 kV管电压CT检查诊断甲状腺癌的符合率为87.50%(14/16)。结论SAFIRE联合80kV管电压实施甲状腺癌CT检查能降低辐射剂量,保持良好图像质量,诊断符合率高。     

双源CT的最新技术与进展研究

介绍了炫速双源CT机的硬件结构,阐述了炫速扫描技术、Stellar探测器技术、能谱纯化技术、FAST CARE技术以及SAFIRE技术是其核心技术,分析了炫速扫描速度、极低的辐射剂量是新一代炫速双源CT的核心特点与优势,最后指出炫速双源CT是双源CT史上的新革命,使CT技术迈入新时代.     

头颅CT平扫100kV结合SAFIRE技术的临床应用效果

目的:探究头颅CT平扫100kV结合SAFIRE技术的临床应用效果。方法:选取2018年1月~2018年12月到本院进行头颅扫描的患者100例作为本次研究对象,根据患者的扫描剂量不同进行分组,分为常规组和低剂量组,每组患者为50例,常规组设置为120kV,低剂量组设置为100kV,其余参数设置相同,均使用机器自动生成的滤波反投影图,低剂量组使用SAFIRE技术,对比两组患者的图像质量主观评分、CT值和辐射剂量。结果:低剂量组患者的CTDIvol、DLP、ED辐射剂量显著低于常规组,差异具有统计学意义(P<0.05);两组患者的脑灰质平均CT值对比,差异具有统计学意义(P<0.05);两组患者的图像质量主观评分对比,差异不具有统计学意义(P>0.05)。结论:头颅CT平扫100kV结合SAFIRE技术在诊断患者疾病中,可在较低辐射剂量下,获得高质量图像。     

Dose reduction with iterative reconstruction: Optimization of CT protocols in clinical practice

ObjectivesTo create an adaptable and global approach for optimizing MDCT protocols by evaluating the influence of acquisition parameters and Iterative Reconstruction (IR) on dose reduction and image quality.Materials and methodsMDCT acquisitions were performed on quality image phantom by varying kVp, mAs, and pitch for the same collimation. The raw data were reconstructed by FBP and Sinogram Affirmed Iterative Reconstruction (SAFIRE) with different reconstruction kernel and thickness. A total of 4032 combinations of parameters were obtained. Indices of quality image (image noise, NCT, CNR, SNR, NPS and MTF) were analyzed. We developed a software in order to facilitate the optimization between dose reduction and image quality. Its outcomes were verified on an adult anthropomorphic phantom.ResultsDose reduction resulted in the increase of image noise and the decrease of SNR and CNR. The use of IR improved these indices for the same dose without affecting NCT and MTF. The image validation was performed by the anthropomorphic phantom. The software proposed combinations of parameters to reduce doses while keeping indices of the image quality adequate. We observed a CTDIvol reduction between −44% and −83% as compared to the French diagnostic reference levels (DRL) for different anatomical localization.ConclusionThe software developed in this study may help radiologists in selecting adequate combinations of parameters that allows to obtain an appropriate image with dose reduction.