Spontaneous pituitary adenoma occurring after resection of a Rathke’s cleft cyst

Rathke’s cleft cysts (RCC) are benign cystic lesions that originate from remnants of the epithelial lining of Rathke’s pouch. RCC are known rarely to occur together with a concomitant pituitary adenoma. Here, we report a patient with a pituitary adenoma arising in the same location as a previously-resected RCC, 3 years post-operatively, and review the literature of “collision” sellar lesions. Consecutive transsphenoidal operations from a single-center between 2008 and 2016 were reviewed to identify patients with pituitary adenoma arising after surgical resection of RCC, and a systematic search of the literature was also performed to identify such patient reports, as well as reports of concomitant pituitary adenoma and RCC. Of 837 transsphenoidal operations from our own experience, one patient with pituitary adenoma occurring after RCC resection was identified and is reported here. A systematic review of the literature resulted in identification of 34 patients with concomitant RCC and pituitary adenoma and no incidents of pituitary adenoma occurring after resection of RCC. Concomitant occurrence of RCC and pituitary adenoma was more commonly diagnosed in women (61%), at a median age of diagnosis of 44 years. The RCC histological analysis in these patients consistently described ciliated columnar or cuboidal epithelium. Although rare, the presence of a new, pathologically-distinct lesions in the sella after prior surgical treatment, is possible. During post-operative monitoring, physicians should consider that what appears as a “recurrent” lesion may actually be growth of a new and entirely different lesion.     

Chemical meningitis: A rare presentation of Rathke’s cleft cyst

Rathke’s cleft cysts (RCC) are usually benign, sellar and/or suprasellar lesions originating from the remnants of Rathke’s pouch. Rarely, RCC can present with chemical meningitis, sellar abscess, lymphocytic hypophysitis, or intracystic hemorrhage. We describe an unusual presentation of RCC in which the patient presented with a clinical picture of chemical meningitis consisting of meningeal irritation, inflammatory cerebrospinal fluid profile, and enhancing pituitary and hypothalamic lesions, in addition to involvement of the optic tracts and optic nerve.     

Multiple occult intracranial diseases diverted diagnosis of glioma in a patient

Dizziness is an atypical symptom of the nervous system. Many neurological disorders can manifest as dizziness. When patients have multiple neurological disorders, the most obvious diagnosis is often considered, and diseases that are potentially more deadly are overlooked. Here, we report the case of a man aged in his early 50s with dizziness who was found to have four neurological disorders. A series of treatments failed to resolve the condition. A review of this case highlights that when a patient’s symptoms are not typical, a comprehensive examination and evaluation is required to determine the etiology, and imaging may reveal further minor problems.     

Rathke裂囊肿的MRI诊断

目的探讨垂体Rathke裂囊肿的MRI表现。材料与方法回顾性分析23例经手术病理证实的Rathke裂囊肿的MRI表现,包括病灶的位置、大小、信号,增强特点及相邻结构的改变。结栗19例位于鞍内,4例位于鞍内鞍上。增强后病灶均无强化。类圆形12例,椭圆形8例,不规则型3例。MRI信号变化多样。部分病例垂体柄、视交叉及鞍底有爱压。结论Rathke裂囊肿在MRI上的信号复杂,依其囊内容物成分而有不同表现,单凭信号及形态与鞍区其它囊性病变难以区分,动态及延迟增强无强化有助于鉴别。     

鞍区Rathke囊肿的MRI诊断及误诊分析

目的分析鞍区RaLhke囊肿的MRl表现,提高对该病的诊断水平。方法回顾性分析经手术与病理证实的24例Rathke囊肿的MRI资料,其中15例进行了动态增强扫描。结果裳肿位于鞍内1O例,鞍内向鞍上延伸14例,多呈圆形、卵圆形或哑铃形,10例正确诊断、11例误诊为垂体瘤,2例误诊为颅咽管瘤,1例误诊为蛛网膜囊肿。结论鞍区Rathke囊肿的MRI表现较典型的特点为：信号多雯,囊内有结节、壁无强化或线样强化,但部分不典型病例需密切结合临床病史与垂体瘤、颅咽管瘤鉴别。     

鞍区Rathke囊肿的MRI诊断

目的:分析Rathke囊肿的MRI特点。方法:病理证实的Rathke囊肿10例,男4例,女6例,年龄18岁～48岁,平均33岁。所有病理均行MRI平扫+增强扫描。分析其MRI表现。结果:病变单纯位于鞍内者5例,单纯鞍上者2例,鞍内鞍上者3例。Rathke囊肿的MRI信号多种多样,一般无明显强化,少数囊壁强化。结论:MRI对Rathke囊肿的诊断有重要价值。     

Rathke囊肿(附71例临床分析)

目的 总结Rathke囊肿的临床表现、影像学、内分泌检查、手术疗效及病理结果 ,探讨其特点和规律.方法 回顾性分析我院1996年1月至2007年3月间经手术和病理证实的71例Rathke囊肿的病例资料.结果 Rathke囊肿女性多发(男:女=1∶1.5).临床表现以头痛、视力视野障碍、内分泌障碍为主.蝶鞍X线检查扩大者3例,其余正常.MRI检查T1WI可为高、低、等信号,T2WI 71.2%为高信号,部分病例增强后囊壁强化.术后33例头痛症状、25例视力视野障碍、6例内分泌障碍症状缓解.术后垂体功能低下者2例,一过性尿崩症8例,电解质紊乱7例.术后复发1例.结论 Rathke囊肿术前诊断困难.但影像学检查有助于诊断.症状性囊肿应手术治疗,手术效果良好,复发率低.     

Rathke囊肿眼科首诊1例

患者女,62岁,因右眼视力下降2年余,于2008年1月16日来我院就诊。2年前右眼无明显诱因出现视物模糊,不能矫正,1年来右眼视力下降加重。既往双眼近视,否认眼外伤及全身病史。眼部检查：视力：双眼裸眼视力0．1,右眼-7．00DS矫正到0．3,左眼-1．00DS矫正到0．8。眼压：右眼17mmHg,左眼19mmHg。双眼裂隙灯检查角膜、虹膜、晶状体未见异常。     

A case report of Turner syndrome associated with Rathke cleft cyst

<正> It has not been reported that Turner syndromecould be associated with Rathke cleft cyst yet,nowwe report such a case found in our hospital.Clinical data:The patient,social sex female,15.3ys,was a junior high school student.Chief com-plaints:She had short stature for 10~+ years and no pu-berche.She was a first full term fetus with cephalicpresentation.The delivery was accomplished by episi-otomy and vacuum extracter with a history of neonatal     

鞍区Rathke囊肿一例及文献复习

目的探讨有症状的Rathke囊肿的诊断和手术治疗方法。方法回顾性分析1例有症状的囊肿的临床表现,影像特点,内分泌改变,术后症状缓解情况。结果该病例内分泌功能紊乱症状完全缓解。结论 Rathke囊肿术前CT与MRI检查均有一定特异性,结合CT与MRI检查能提高Rathke囊肿术前诊断率。经鼻-蝶窦入路显微手术是目前治疗Rathke囊肿的最佳方法。