射频与中药联合治疗肥厚性咽炎的临床观察

目的 :探讨应用射频与中药联合治疗肥厚性咽炎的疗效。方法 :随机将 16 8例肥厚性咽炎患者分为射频与中药联合治疗组和对照组 ,进行临床观察。结果 :治疗组显效率 76 .3% ,总有效率 10 0 % ,对照组显效率 14 % ,总有效率 82 % ,两组差异有高度显著性 (P<0 .0 1)。 结论 :射频配合中药联合治疗肥厚性咽炎效果显著。     

Optimal site for throat culture: tonsillar surface versus posterior pharyngeal wall

To determine the optimal site of throat culture for the detection of potential pathogens by comparing culture results from the tonsillar surface and the posterior pharyngeal wall in children selected for adenotonsillectomy and in children without upper respiratory disease. Cotton culture swabs were taken from the tonsillar surface and the posterior pharyngeal wall of 50 children selected for adenotonsillectomy for symptoms of recurrent tonsillitis and/or adenotonsillar hypertrophy and of 50 children without upper respiratory disease. Potential respiratory pathogens were identified. In the overall group (n = 100), positive culture results were found in 67 posterior pharyngeal wall samples and 47 tonsillar surface samples (P = 0.001). Haemophilus influenzae was the most frequently isolated micro-organism both in the posterior pharyngeal wall and the tonsillar surface samples; 55 and 35%, respectively (P = 0.001). Group A beta-haemolytic streptococci were found in the samples of the posterior pharyngeal wall and the tonsillar surface in 17 and 13%, respectively (P = 0.2). When dealing with patients with sore throat, sampling both tonsillar surfaces is enough for the detection of group A beta-haemolytic streptococci. When detection of other bacteria is also important, such as for research purposes, the posterior pharyngeal wall should be sampled as well.     

Changing perspectives in children hospitalized with poststreptococcal acute glomerulonephritis

Changing perspectives in 95 children with poststreptococcal acute glomerulonephritis (PSAGN) in our hospital between 1979 and 1988 are reported. Between 1961 and 1970 an average of 31±6.3 patients/year with PSAGN were treated and 70% had antecedent pyoderma. In the present study antecedent pharyngitis was observed in 59 children und pyoderma in 36. In comparison to the decade ending in 1970 our data show: (1) a marked decline in the prevalence of PSAGN (P=<0.0005), (2) a predominance of antecedent pharyngeal infection (P=0.044), (3) a decline in urban and an increase in rural patients with PSAGN (P=0.0483); and in the last decade: (1) a predominance of antecedent pharyngeal infection in children over 6 years of age (P=0.0009) and (2) a predominance of antecedent pyoderma in black children (P=0.0004).     

中药组方“清音饮”治疗慢性咽炎

目的：总结中药组方“清音饮”治疗慢性咽炎的疗效,探讨其机理。方法：用“清音饮”治疗慢性咽炎１０６０例。结果：总有效率为９６．６％,此方剂组成成分具有抗炎、镇痛、解热、抑菌、增加腺体分泌及提高机体免疫的功能。结论：“清音饮”是治疗慢性咽炎较理想的方剂。     

半夏泻心汤为主治疗胃食管反流性咽喉炎40例临床观察

目的:观察以半夏泻心汤为主治疗胃食管反流病(GERD)引起的咽喉炎.方法:治疗组40例以半夏泻心汤为主治疗,对照组38例给予金嗓利咽丸治疗.结果:两组咽喉炎并发症疗效、GERD症状疗效、胃镜分级疗效、喉镜检查比较,治疗组明显优于对照组(P＜0.05或P＜0.01).结论:半夏泻心汤为主治疗胃食管反流病引起的咽喉炎具有较好疗效.     

雾化吸入治疗咽喉炎的临床效果研究

目的：研究分析雾化吸入治疗咽喉炎的临床效果。方法选取2011年12月—2013年12月在该院确诊收治的130例咽喉炎患者作为研究对象,将所有患者随机分为对照组和观察组各65例,对照组患者给予氨苄西林胶囊和地塞米松进行口服治疗,观察组患者给予庆大霉素及地塞米松雾化吸入治疗,观察两组患者的临床治疗效果以及各项临床症状改善时间情况,并作对比分析。结果观察组患者的临床治疗有效率为95.38%,明显高于对照组的74.85%,两组对比差异有统计学意义（P<0.05）;观察组患者咳嗽、咽痛、滤泡增生和咽喉部红肿等临床症状消失时间明显少于对照组,两组对比差异有统计学意义（P<0.05）。结论采用雾化吸入治疗咽喉炎具有较高的临床应用价值,疗效确切,能够有效祛痰、镇咳,缓解患者临床症状,值得临床大力推广。     

Diagnostic accuracy of rapid nucleic acid tests for group A streptococcal pharyngitis: systematic review and meta-analysis

BackgroundAcute pharyngitis is one of the most common conditions in outpatient settings and an important source of inappropriate antibiotic prescribing. Rapid antigen detection tests (RADTs) offer diagnosis of group A streptococcus at the point of care but have limited sensitivity. Rapid nucleic acid tests (RNATs) are now available; a systematic review of their accuracy is lacking.ObjectivesTo evaluate the accuracy of RNATs in patients with pharyngitis; to explore test-level and study-level factors that could explain variability in accuracy; and to compare the accuracy of RNATs with that of RADTs.Data sourcesMEDLINE, Embase, Web of Science (1990–2020).Study eligibility criteriaCross-sectional studies and randomized trials.ParticipantsPatients with pharyngitis.Index test/s and reference standardsRNAT commercial kits compared with throat culture.MethodsWe assessed risk of bias and applicability using QUADAS-2. We performed meta-analysis of sensitivity and specificity using the bivariate random-effects model. Variability was explored by subgroup analyses and meta-regression.ResultsWe included 38 studies (46 test evaluations; 17 411 test results). RNATs were most often performed in a laboratory. The overall methodological quality of primary studies was uncertain because of incomplete reporting. RNATs had a summary sensitivity of 97.5% (95% CI 96.2%–98.3%) and a summary specificity of 95.1% (95% CI 93.6%–96.3%). There was low variability in estimates across studies. Variability in sensitivity and specificity was partially explained by test type (p < 0.05 for both). Sensitivity analyses limited to studies with low risk of bias showed robust accuracy estimates. RNATs were more sensitive than RADTs (13 studies; 96.8% versus 82.3%, p 0.004); there was no difference in specificity (p 0.92).ConclusionsThe high diagnostic accuracy of RNATs may allow their use as stand-alone tests to diagnose group A streptococcus pharyngitis. Based on direct comparisons, RNATs have greater sensitivity than RADTs and equal specificity. Further studies should evaluate RNATs in point-of-care settings.     

低温等离子射频消融术联合金莲花软胶囊治疗肥厚性咽炎的临床疗效探讨

目的探讨低温等离子射频消融术联合金莲花软胶囊治疗慢性肥厚性咽炎的临床效果。方法选取慢性肥厚性咽炎患者共80例,随机分为观察组和对照组各40例。其中观察组采用低温等离子射频消融术联合金莲花软胶囊进行治疗,对照组采用金莲花软胶囊进行治疗,比较两组患者的临床疗效。结果治疗后,观察组的与对照组的总有效率分别为98.2%、72.7%,观察组的总有效率明显高于对照组,差异均具有统计学意义。结论低温等离子射频消融术联合金莲花软胶囊治疗慢性肥厚性咽炎效果显著,具有临床应用及推广价值。